Decreased A-to-I RNA editing as a source of keratinocytes' dsRNA in psoriasis

Dynamic landscape and regulation of RNA editing in mammals

(2017) Meng How Tan et al.   NATURE

Pathway Analysis of Skin from Psoriasis Patients after Adalimumab Treatment Reveals New Early Events in the Anti-Inflammatory Mechanism of Anti-TNF-α

(2017) Ane Langkilde et al.   PLoS One

Abnormalities in A-to-I RNA editing patterns in CNS injuries correlate with dynamic changes in cell type composition

(2017) Nurit Gal-Mark et al.   Scientific Reports

Network analysis of psoriasis reveals biological pathways and roles for coding and long non-coding RNAs

(2016) Richard Ahn et al.   BMC GENOMICS

Antimicrobial Peptide LL37 and MAVS Signaling Drive Interferon-β Production by Epidermal Keratinocytes during Skin Injury

(2016) Ling-juan Zhang et al.   IMMUNITY

Expression of sirtuins 1, 6, tumor necrosis factor, and interferon-γ in psoriatic patients

(2016) H Rasheed et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

Landscape of Long Noncoding RNAs in Psoriatic and Healthy Skin

(2016) Rashmi Gupta et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Molecular and Cellular Profiling of Scalp Psoriasis Reveals Differences and Similarities Compared to Skin Psoriasis

(2016) Juan Ruano et al.   PLoS One

Treating psoriasis with adalimumab

(2016) Kenneth Gordon   Therapeutics and Clinical Risk Management

Isoforms of RNA-Editing Enzyme ADAR1 Independently Control Nucleic Acid Sensor MDA5-Driven Autoimmunity and Multi-organ Development

(2015) Kathleen Pestal et al.   IMMUNITY

COPA mutations impair ER-Golgi transport and cause hereditary autoimmune-mediated lung disease and arthritis

(2015) Levi B Watkin et al.   NATURE GENETICS

RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself

(2015) B. J. Liddicoat et al.   SCIENCE

Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation

(2015) S. Liu et al.   SCIENCE

Elevated RNA Editing Activity Is a Major Contributor to Transcriptomic Diversity in Tumors

(2015) Nurit Paz-Yaacov et al.   Cell Reports

Analysis of long non-coding RNAs highlights tissue-specific expression patterns and epigenetic profiles in normal and psoriatic skin

(2015) Lam C Tsoi et al.   GENOME BIOLOGY

Immunology of Psoriasis

(2014) Michelle A. Lowes et al.   Annual Review of Immunology

Gene Expression Profiles Normalized in Psoriatic Skin by Treatment with Brodalumab, a Human Anti-IL-17 Receptor Monoclonal Antibody

(2014) C. B. Russell et al.   JOURNAL OF IMMUNOLOGY

Transcriptome Analysis of Psoriasis in a Large Case–Control Sample: RNA-Seq Provides Insights into Disease Mechanisms

(2014) Bingshan Li et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Genome-wide analysis of Alu editability

(2014) L. Bazak et al.   NUCLEIC ACIDS RESEARCH

Characterizing of functional human coding RNA editing from evolutionary, structural, and dynamic perspectives

(2014) Oz Solomon et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

A genome-wide map of hyper-edited RNA reveals numerous new sites

(2014) Hagit T. Porath et al.   Nature Communications

The RNA-Editing Enzyme ADAR1 Controls Innate Immune Responses to RNA

(2014) Niamh M. Mannion et al.   Cell Reports

Mammalian conserved ADAR targets comprise only a small fragment of the human editosome

(2014) Yishay Pinto et al.   GENOME BIOLOGY

Pattern Recognition and Signaling Mechanisms of RIG-I and MDA5

(2014) Stephanie Reikine et al.   Frontiers in Immunology

Insulin-like growth factor-binding protein-7 (IGFBP7) transcript: A-to-I editing events in normal and cancerous human keratinocytes

(2013) Malka Hochberg et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

REDItools: high-throughput RNA editing detection made easy

(2013) Ernesto Picardi et al.   BIOINFORMATICS

ADAR1 Forms a Complex with Dicer to Promote MicroRNA Processing and RNA-Induced Gene Silencing

(2013) Hiromitsu Ota et al.   CELL

A-to-I RNA editing occurs at over a hundred million genomic sites, located in a majority of human genes

(2013) L. Bazak et al.   GENOME RESEARCH

Identifying RNA editing sites using RNA sequencing data alone

(2013) Gokul Ramaswami et al.   NATURE METHODS

RADAR: a rigorously annotated database of A-to-I RNA editing

(2013) Gokul Ramaswami et al.   NUCLEIC ACIDS RESEARCH

A high-throughput screen to identify enhancers of ADAR-mediated RNA-editing

(2013) Wojciech Garncarz et al.   RNA Biology

ADAR Regulates RNA Editing, Transcript Stability, and Gene Expression

(2013) Isabel X. Wang et al.   Cell Reports

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

IGFBP7's susceptibility to proteolysis is altered by A-to-I RNA editing of its transcript

(2012) Christina Godfried Sie et al.   FEBS LETTERS

Induction and exacerbation of psoriasis with Interferon-alpha therapy for hepatitis C: A review and analysis of 36 cases

(2012) M. Afshar et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature

(2012) Gillian I Rice et al.   NATURE GENETICS

The ADAR protein family

(2012) Yiannis A Savva et al.   GENOME BIOLOGY

Psoriasis

(2011) Gayathri K. Perera et al.   Annual Review of Pathology-Mechanisms of Disease

Accurate identification of A-to-I RNA editing in human by transcriptome sequencing

(2011) J. H. Bahn et al.   GENOME RESEARCH

IGFBP7 as a Potential Therapeutic Target in Psoriasis

(2011) Janna Nousbeck et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Identification of Widespread Ultra-Edited Human RNAs

(2011) Shai Carmi et al.   PLoS Genetics

Functions and Regulation of RNA Editing by ADAR Deaminases

(2010) Kazuko Nishikura   Annual Review of Biochemistry

Induction of type I interferons by bacteria

(2010) Kathryn M. Monroe et al.   CELLULAR MICROBIOLOGY

Type I interferon: friend or foe?

(2010) Giorgio Trinchieri   JOURNAL OF EXPERIMENTAL MEDICINE

Effective Narrow-Band UVB Radiation Therapy Suppresses the IL-23/IL-17 Axis in Normalized Psoriasis Plaques

(2010) Leanne M. Johnson-Huang et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Carriers of Rare Missense Variants in IFIH1 Are Protected from Psoriasis

(2010) Yonghong Li et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

(2010) K. Wang et al.   NUCLEIC ACIDS RESEARCH

Increased A-to-I RNA editing of the transcript for GABAA receptor subunit α3 during chick retinal development

(2010) HENRIK RING et al.   VISUAL NEUROSCIENCE

Differential expression analysis for sequence count data

(2010) Simon Anders et al.   GENOME BIOLOGY

ADAR1 and ADAR2 Expression and Editing Activity during Forebrain Development

(2009) Michelle M. Jacobs et al.   DEVELOPMENTAL NEUROSCIENCE

Large-scale mRNA sequencing determines global regulation of RNA editing during brain development

(2009) H. Wahlstedt et al.   GENOME RESEARCH

RNA-specific Adenosine Deaminase ADAR1 Suppresses Measles Virus-induced Apoptosis and Activation of Protein Kinase PKR

(2009) Ann M. Toth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Self-RNA–antimicrobial peptide complexes activate human dendritic cells through TLR7 and TLR8

(2009) Dipyaman Ganguly et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Psoriasis during interferon beta treatment for multiple sclerosis

(2009) Loredana La Mantia et al.   NEUROLOGICAL SCIENCES

Altered editing in cyclic nucleotide phosphodiesterase 8A1 gene transcripts of systemic lupus erythematosus T lymphocytes

(2008) Robert J. Orlowski et al.   IMMUNOLOGY

ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling

(2008) Jochen C Hartner et al.   NATURE IMMUNOLOGY

Type I Interferon: Potential Therapeutic Target for Psoriasis?

(2008) Yihong Yao et al.   PLoS One

IFN-α Enhances Poly-IC Responses in Human Keratinocytes by Inducing Expression of Cytosolic Innate RNA Receptors: Relevance for Psoriasis

(2007) Errol P. Prens et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY