Interaction of antidiabetic α-glucosidase inhibitors and gut bacteria α-glucosidase

Structure of human lysosomal acid α-glucosidase–a guide for the treatment of Pompe disease

(2017) Véronique Roig-Zamboni et al.   Nature Communications

Human gut microbiota plays a role in the metabolism of drugs

(2016) Lenka Jourova et al.   BIOMEDICAL PAPERS-OLOMOUC

Effects of orally administered antibiotics on the bioavailability of amlodipine

(2016) Hye Hyun Yoo et al.   JOURNAL OF HYPERTENSION

The influence of gut microbiota on drug metabolism and toxicity

(2015) Houkai Li et al.   Expert Opinion on Drug Metabolism & Toxicology

Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota

(2015) Kristoffer Forslund et al.   NATURE

Reclassification of Ruminococcus obeum as Blautia obeum comb. nov.

(2014) P. A. Lawson et al.   INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY

Xenobiotics Shape the Physiology and Gene Expression of the Active Human Gut Microbiome

(2013) Corinne Ferrier Maurice et al.   CELL

The effect of gut microbiota on drug metabolism

(2013) Mi Jeong Kang et al.   Expert Opinion on Drug Metabolism & Toxicology

Gut Pharmacomicrobiomics: the tip of an iceberg of complex interactions between drugs and gut-associated microbes

(2013) Rama Saad et al.   Gut Pathogens

Efficacy and Safety Profile Evaluation of Acarbose Alone and in Association With Other Antidiabetic Drugs: A Systematic Review

(2012) Giuseppe Derosa et al.   CLINICAL THERAPEUTICS

Alpha-glucosidase inhibitors 2012 – cardiovascular considerations and trial evaluation

(2012) Eberhard Standl et al.   Diabetes & Vascular Disease Research

The synthesis and biological evaluation of 1-C-alkyl-l-arabinoiminofuranoses, a novel class of α-glucosidase inhibitors

(2010) Yoshihiro Natori et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Novel α-glucosidase from human gut microbiome: substrate specificities and their switch

(2010) Kemin Tan et al.   FASEB JOURNAL

Structural Basis for Substrate Selectivity in Human Maltase-Glucoamylase and Sucrase-Isomaltase N-terminal Domains

(2010) Lyann Sim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alleviating Cancer Drug Toxicity by Inhibiting a Bacterial Enzyme

(2010) B. D. Wallace et al.   SCIENCE

New Glucosidase Inhibitors from an Ayurvedic Herbal Treatment for Type 2 Diabetes: Structures and Inhibition of Human Intestinal Maltase-Glucoamylase with Compounds fromSalacia reticulata

(2009) Lyann Sim et al.   BIOCHEMISTRY

The NIH Human Microbiome Project

(2009) et al.   GENOME RESEARCH

In vitro inhibition of glycogen-degrading enzymes and glycosidases by six-membered sugar mimics and their evaluation in cell cultures

(2008) Chinami Kuriyama et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Gut microbiota modulation with norfloxacin and ampicillin enhances glucose tolerance in mice

(2008) Mathieu Membrez et al.   FASEB JOURNAL

The gastrointestinal microbiota as a site for the biotransformation of drugs

(2008) Tiago Sousa et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

The Carbohydrate-Active EnZymes database (CAZy): an expert resource for Glycogenomics

(2008) B. L. Cantarel et al.   NUCLEIC ACIDS RESEARCH

Cell-wall carbohydrates and their modification as a resource for biofuels

(2008) Markus Pauly et al.   PLANT JOURNAL

The convergence of carbohydrate active gene repertoires in human gut microbes

(2008) C. A. Lozupone et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human Intestinal Maltase–Glucoamylase: Crystal Structure of the N-Terminal Catalytic Subunit and Basis of Inhibition and Substrate Specificity

(2007) Lyann Sim et al.   JOURNAL OF MOLECULAR BIOLOGY