Identification of a highly neurotoxic α-synuclein species inducing mitochondrial damage and mitophagy in Parkinson’s disease
出版年份 2018 全文链接
标题
Identification of a highly neurotoxic α-synuclein species inducing mitochondrial damage and mitophagy in Parkinson’s disease
作者
关键词
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出版物
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 115, Issue 11, Pages E2634-E2643
出版商
Proceedings of the National Academy of Sciences
发表日期
2018-02-28
DOI
10.1073/pnas.1713849115
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- T cells from patients with Parkinson’s disease recognize α-synuclein peptides
- (2017) David Sulzer et al. NATURE
- Asparagine endopeptidase cleaves α-synuclein and mediates pathologic activities in Parkinson's disease
- (2017) Zhentao Zhang et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Asparagine endopeptidase cleaves α-synuclein and mediates pathologic activities in Parkinson's disease
- (2017) Zhentao Zhang et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Mutations of glucocerebrosidase gene and susceptibility to Parkinson’s disease: An updated meta-analysis in a European population
- (2016) F. Zhao et al. NEUROSCIENCE
- AMP-activated protein kinase mediates mitochondrial fission in response to energy stress
- (2016) E. Q. Toyama et al. SCIENCE
- α-Synuclein binds to TOM20 and inhibits mitochondrial protein import in Parkinson’s disease
- (2016) Roberto Di Maio et al. Science Translational Medicine
- There's Something Wrong with my MAM; the ER–Mitochondria Axis and Neurodegenerative Diseases
- (2016) Sebastien Paillusson et al. TRENDS IN NEUROSCIENCES
- Functionally different α-synuclein inclusions yield insight into Parkinson’s disease pathology
- (2016) Christian C. Raiss et al. Scientific Reports
- Implication of Alpha-Synuclein Phosphorylation at S129 in Synucleinopathies: What Have We Learned in the Last Decade?
- (2016) Abid Oueslati Journal of Parkinsons Disease
- The endoplasmic reticulum/mitochondria interface: a subcellular platform for the orchestration of the functions of the PINK1–Parkin pathway?: Figure 1
- (2015) Zoi Erpapazoglou et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- α-Synuclein and Lewy pathology in Parkinsonʼs disease
- (2015) Lorraine V. Kalia et al. CURRENT OPINION IN NEUROLOGY
- Oxidative Stress Attenuates Lipid Synthesis and Increases Mitochondrial Fatty Acid Oxidation in Hepatoma Cells Infected with Hepatitis C Virus
- (2015) Donna N. Douglas et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MitoCarta2.0: an updated inventory of mammalian mitochondrial proteins
- (2015) Sarah E. Calvo et al. NUCLEIC ACIDS RESEARCH
- Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism
- (2015) Stanley B. Prusiner et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Aggregated α-synuclein and complex I deficiency: exploration of their relationship in differentiated neurons
- (2015) A K Reeve et al. Cell Death & Disease
- New functions of mitochondria associated membranes in cellular signaling
- (2014) Alexander R. van Vliet et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Formation of α-synuclein Lewy neurite–like aggregates in axons impedes the transport of distinct endosomes
- (2014) Laura A. Volpicelli-Daley et al. MOLECULAR BIOLOGY OF THE CELL
- Addition of exogenous α-synuclein preformed fibrils to primary neuronal cultures to seed recruitment of endogenous α-synuclein to Lewy body and Lewy neurite–like aggregates
- (2014) Laura A Volpicelli-Daley et al. Nature Protocols
- Ubiquitin-independent proteasomal degradation
- (2013) Jenny Erales et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Distinct α-Synuclein Strains Differentially Promote Tau Inclusions in Neurons
- (2013) Jing L. Guo et al. CELL
- Lewy Body-like α-Synuclein Aggregates Resist Degradation and Impair Macroautophagy
- (2013) Selcuk A. Tanik et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Calcium Entry and -Synuclein Inclusions Elevate Dendritic Mitochondrial Oxidant Stress in Dopaminergic Neurons
- (2013) D. I. Dryanovski et al. JOURNAL OF NEUROSCIENCE
- Mitochondrial reactive oxygen species enhance AMP-activated protein kinase activation in the endothelium of patients with coronary artery disease and diabetes
- (2012) Ruth M. Mackenzie et al. CLINICAL SCIENCE
- Blocking c-Jun N-terminal Kinase (JNK) Translocation to the Mitochondria Prevents 6-Hydroxydopamine-induced Toxicityin Vitroandin Vivo
- (2012) Jeremy W. Chambers et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Exosomal cell-to-cell transmission of alpha synuclein oligomers
- (2012) Karin M Danzer et al. Molecular Neurodegeneration
- The many faces of α-synuclein: from structure and toxicity to therapeutic target
- (2012) Hilal A. Lashuel et al. NATURE REVIEWS NEUROSCIENCE
- Pathological -Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
- (2012) K. C. Luk et al. SCIENCE
- Recent Advances in the Genetics of Parkinson's Disease
- (2011) Ian Martin et al. Annual Review of Genomics and Human Genetics
- α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells
- (2011) Christian Hansen et al. JOURNAL OF CLINICAL INVESTIGATION
- Exogenous α-Synuclein Fibrils Induce Lewy Body Pathology Leading to Synaptic Dysfunction and Neuron Death
- (2011) Laura A. Volpicelli-Daley et al. NEURON
- In vivo demonstration that -synuclein oligomers are toxic
- (2011) B. Winner et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Impaired mitochondrial dynamics and function in the pathogenesis of Parkinson's disease
- (2009) Hansruedi Büeler EXPERIMENTAL NEUROLOGY
- Exogenous -synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells
- (2009) K. C. Luk et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation
- (2008) Jia-Yi Li et al. NATURE MEDICINE
- Lewy body–like pathology in long-term embryonic nigral transplants in Parkinson's disease
- (2008) Jeffrey H Kordower et al. NATURE MEDICINE
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