A common molecular signature of patients with sickle cell disease revealed by microarray meta-analysis and a genome-wide association study

Alteration of lymphocyte phenotype and function in sickle cell anemia: Implications for vaccine responses

(2016) Emmanuel Balandya et al.   AMERICAN JOURNAL OF HEMATOLOGY

Neutrophils, platelets, and inflammatory pathways at the nexus of sickle cell disease pathophysiology

(2016) D. Zhang et al.   BLOOD

Inferring active regulatory networks from gene expression data using a combination of prior knowledge and enrichment analysis

(2016) Panagiotis Chouvardas et al.   BMC BIOINFORMATICS

Meta-analysis of gene expression profiles identifies differential biomarkers for hepatocellular carcinoma and cholangiocarcinoma

(2016) Somsak Likhitrattanapisal et al.   TUMOR BIOLOGY

Large Scale Gene Expression Meta-Analysis Reveals Tissue-Specific, Sex-Biased Gene Expression in Humans

(2016) Benjamin T. Mayne et al.   Frontiers in Genetics

Meta-Analysis of Genome-Wide Association Studies and Network Analysis-Based Integration with Gene Expression Data Identify New Suggestive Loci and Unravel a Wnt-Centric Network Associated with Dupuytren’s Disease

(2016) Kerstin Becker et al.   PLoS One

Comprehensive Gene expression meta-analysis and integrated bioinformatic approaches reveal shared signatures between thrombosis and myeloproliferative disorders

(2016) Prabhash Kumar Jha et al.   Scientific Reports

Bacteraemia in sickle cell anaemia is associated with low haemoglobin: a report of 890 admissions to a tertiary hospital in Tanzania

(2015) Julie Makani et al.   BRITISH JOURNAL OF HAEMATOLOGY

Serum IL-6, IL-10, and TNFα levels in pediatric sickle cell disease patients during vasoocclusive crisis and steady state condition

(2015) Sameh Sarray et al.   CYTOKINE

NetworkAnalyst for statistical, visual and network-based meta-analysis of gene expression data

(2015) Jianguo Xia et al.   Nature Protocols

Role of innate immunity-triggered pathways in the pathogenesis of Sickle Cell Disease: a meta-analysis of gene expression studies

(2015) Bidossessi Wilfried Hounkpe et al.   Scientific Reports

Increased Heme Levels in the Heart Lead to Exacerbated Ischemic Injury

(2015) Konrad Teodor Sawicki et al.   Journal of the American Heart Association

Anti-CD44 Antibody Treatment Lowers Hyperglycemia and Improves Insulin Resistance, Adipose Inflammation, and Hepatic Steatosis in Diet-Induced Obese Mice

(2014) Keiichi Kodama et al.   DIABETES

Heme and erythropoieis: more than a structural role

(2014) D. Chiabrando et al.   HAEMATOLOGICA

Ischemia-reperfusion Injury in Sickle Cell Anemia

(2014) Robert P. Hebbel   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Inflammatory Mediators of Endothelial Injury in Sickle Cell Disease

(2014) Carolyn C. Hoppe   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

STRING v10: protein–protein interaction networks, integrated over the tree of life

(2014) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Genome Wide Association Study of Fetal Hemoglobin in Sickle Cell Anemia in Tanzania

(2014) Siana Nkya Mtatiro et al.   PLoS One

Genomic architecture of sickle cell disease in West African children

(2014) Jacklyn Quinlan et al.   Frontiers in Genetics

Partial dysfunction of Treg activation in sickle cell disease

(2013) Benoît Vingert et al.   AMERICAN JOURNAL OF HEMATOLOGY

MP4CO, a pegylated hemoglobin saturated with carbon monoxide, is a modulator of HO-1, inflammation, and vaso-occlusion in transgenic sickle mice

(2013) J. D. Belcher et al.   BLOOD

HO-1 and CO: fighters vs sickle cell disease?

(2013) J. A. Araujo   BLOOD

Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool

(2013) Edward Y Chen et al.   BMC BIOINFORMATICS

Transcription factor nuclear factor erythroid-2 mediates expression of the cytokine interleukin 8, a known predictor of inferior outcome in patients with myeloproliferative neoplasms

(2013) J. Wehrle et al.   HAEMATOLOGICA

Out of Balance—Systemic Iron Homeostasis in Iron-Related Disorders

(2013) Andrea Steinbicker et al.   Nutrients

Integrating GWAS and Expression Data for Functional Characterization of Disease-Associated SNPs: An Application to Follicular Lymphoma

(2012) Lucia Conde et al.   AMERICAN JOURNAL OF HUMAN GENETICS

An R package suite for microarray meta-analysis in quality control, differentially expressed gene analysis and pathway enrichment detection

(2012) Xingbin Wang et al.   BIOINFORMATICS

A systematic comparison and evaluation of high density exon arrays and RNA-seq technology used to unravel the peripheral blood transcriptome of sickle cell disease

(2012) Nalini Raghavachari et al.   BMC Medical Genomics

Calcium/Calmodulin-dependent Protein Kinase Kinase 2 Regulates Macrophage-mediated Inflammatory Responses

(2012) Luigi Racioppi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A novel murine model of myeloproliferative disorders generated by overexpression of the transcription factor NF-E2

(2012) Kai B. Kaufmann et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Global epidemiology of sickle haemoglobin in neonates: a contemporary geostatistical model-based map and population estimates

(2012) Frédéric B Piel et al.   LANCET

Reuse of public genome-wide gene expression data

(2012) Johan Rung et al.   NATURE REVIEWS GENETICS

Comprehensive literature review and statistical considerations for microarray meta-analysis

(2012) George C. Tseng et al.   NUCLEIC ACIDS RESEARCH

Expression-based genome-wide association study links the receptor CD44 in adipose tissue with type 2 diabetes

(2012) K. Kodama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systematic Localization of Common Disease-Associated Variation in Regulatory DNA

(2012) M. T. Maurano et al.   SCIENCE

Biomarkers of Inflammation, Growth Factor, and Coagulation Activation in Patients With Sickle Cell Disease

(2011) M. H. Qari et al.   CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS

Ten novel mutations in the erythroid transcription factor KLF1 gene associated with increased fetal hemoglobin levels in adults

(2011) A. E. Gallienne et al.   HAEMATOLOGICA

Sickle-cell disease

(2010) David C Rees et al.   LANCET

Increased risk of invasive bacterial infections in African people with sickle-cell disease: a systematic review and meta-analysis

(2010) Meenakshi Ramakrishnan et al.   LANCET INFECTIOUS DISEASES

Heme Degradation and Vascular Injury

(2009) John D. Belcher et al.   ANTIOXIDANTS & REDOX SIGNALING

Biomarker detection in the integration of multiple multi-class genomic studies

(2009) Shuya Lu et al.   BIOINFORMATICS

ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

(2009) Gabriela Bindea et al.   BIOINFORMATICS

Newer Aspects of the Pathophysiology of Sickle Cell Disease Vaso-Occlusion

(2009) Nicola Conran et al.   HEMOGLOBIN

Characterization of Whole Blood Gene Expression Profiles as a Sequel to Globin mRNA Reduction in Patients with Sickle Cell Disease

(2009) Nalini Raghavachari et al.   PLoS One

GWAS Meets Microarray: Are the Results of Genome-Wide Association Studies and Gene-Expression Profiling Consistent? Prostate Cancer as an Example

(2009) Ivan P. Gorlov et al.   PLoS One

Clinical Utility of Microarrays: Current Status, Existing Challenges and Future Outlook

(2008) Xinmin Li et al.   CURRENT GENOMICS

Altered levels of cytokines and inflammatory mediators in plasma and leukocytes of sickle cell anemia patients and effects of hydroxyurea therapy

(2008) C. Lanaro et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Meta-analysis for ranked discovery datasets: Theoretical framework and empirical demonstration for microarrays

(2007) Elias Zintzaras et al.   COMPUTATIONAL BIOLOGY AND CHEMISTRY