The mechanisms how heparin affects the tumor cell induced VEGF and chemokine release from platelets to attenuate the early metastatic niche formation

Neutrophils Suppress Intraluminal NK Cell-Mediated Tumor Cell Clearance and Enhance Extravasation of Disseminated Carcinoma Cells

(2016) A. Spiegel et al.   Cancer Discovery

CCL2-induced chemokine cascade promotes breast cancer metastasis by enhancing retention of metastasis-associated macrophages

(2015) Takanori Kitamura et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Epithelial–Mesenchymal Plasticity: A Central Regulator of Cancer Progression

(2015) Xin Ye et al.   TRENDS IN CELL BIOLOGY

Platelets and cancer: a casual or causal relationship: revisited

(2014) David G. Menter et al.   CANCER AND METASTASIS REVIEWS

Tumor-Associated Macrophages: From Mechanisms to Therapy

(2014) Roy Noy et al.   IMMUNITY

A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages

(2014) Haihui Lu et al.   NATURE CELL BIOLOGY

Platelets guide the formation of early metastatic niches

(2014) M. Labelle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The cellular and molecular origin of tumor-associated macrophages

(2014) R. A. Franklin et al.   SCIENCE

Anticoagulation inhibits tumor cell-mediated release of platelet angiogenic proteins and diminishes platelet angiogenic response

(2013) E. M. Battinelli et al.   BLOOD

Recruitment of monocytes/macrophages by tissue factor-mediated coagulation is essential for metastatic cell survival and premetastatic niche establishment in mice

(2012) A. M. Gil-Bernabe et al.   BLOOD

Intratumoral macrophages contribute to epithelial-mesenchymal transition in solid tumors

(2012) Anne-Katrine Bonde et al.   BMC CANCER

Endothelial CCR2 Signaling Induced by Colon Carcinoma Cells Enables Extravasation via the JAK2-Stat5 and p38MAPK Pathway

(2012) Monika Julia Wolf et al.   CANCER CELL

Semuloparin for Thromboprophylaxis in Patients Receiving Chemotherapy for Cancer

(2012) Giancarlo Agnelli et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Initial Hours of Metastasis: The Importance of Cooperative Host-Tumor Cell Interactions during Hematogenous Dissemination

(2012) M. Labelle et al.   Cancer Discovery

Identification of Luminal Breast Cancers That Establish a Tumor-Supportive Macroenvironment Defined by Proangiogenic Platelets and Bone Marrow-Derived Cells

(2012) H. S. Kuznetsov et al.   Cancer Discovery

Distinct platelet packaging, release, and surface expression of proangiogenic and antiangiogenic factors on different platelet stimuli

(2011) M. Chatterjee et al.   BLOOD

Platelets Alter Tumor Cell Attributes to Propel Metastasis: Programming in Transit

(2011) Laurie J. Gay et al.   CANCER CELL

VCAM-1 Promotes Osteolytic Expansion of Indolent Bone Micrometastasis of Breast Cancer by Engaging α4β1-Positive Osteoclast Progenitors

(2011) Xin Lu et al.   CANCER CELL

Macrophage Binding to Receptor VCAM-1 Transmits Survival Signals in Breast Cancer Cells that Invade the Lungs

(2011) Qing Chen et al.   CANCER CELL

Targeting the ANG2/TIE2 Axis Inhibits Tumor Growth and Metastasis by Impairing Angiogenesis and Disabling Rebounds of Proangiogenic Myeloid Cells

(2011) Roberta Mazzieri et al.   CANCER CELL

Direct Signaling between Platelets and Cancer Cells Induces an Epithelial-Mesenchymal-Like Transition and Promotes Metastasis

(2011) Myriam Labelle et al.   CANCER CELL

Paracrine and Autocrine Signals Induce and Maintain Mesenchymal and Stem Cell States in the Breast

(2011) Christina Scheel et al.   CELL

Modulation of Natural Killer Cell Anti-Tumor Reactivity by Platelets

(2011) Theresa Placke et al.   Journal of Innate Immunity

CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis

(2011) Bin-Zhi Qian et al.   NATURE

Antimetastatic activities of heparins and modified heparins. Experimental evidence

(2010) Lubor Borsig   THROMBOSIS RESEARCH

Selectin-mediated activation of endothelial cells induces expression of CCL5 and promotes metastasis through recruitment of monocytes

(2009) H. Laubli et al.   BLOOD

Role of Tissue Factor in Cancer

(2009) Raj S. Kasthuri et al.   JOURNAL OF CLINICAL ONCOLOGY

Platelet glycoprotein VI facilitates experimental lung metastasis in syngenic mouse models

(2009) S. JAIN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

A Distinct Macrophage Population Mediates Metastatic Breast Cancer Cell Extravasation, Establishment and Growth

(2009) Binzhi Qian et al.   PLoS One

Platelets actively sequester angiogenesis regulators

(2008) G. Lakka Klement et al.   BLOOD

Platelet Granule Secretion Continuously Prevents Intratumor Hemorrhage

(2008) B. Ho-Tin-Noe et al.   CANCER RESEARCH