Staphylococcus aureus protein A causes osteoblasts to hyper-mineralise in a 3D extra-cellular matrix environment

Staphylococcal protein A promotes osteoclastogenesis through MAPK signaling during bone infection

(2017) Yuan Wang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Staphylococcus aureus protein A enhances osteoclastogenesis via TNFR1 and EGFR signaling

(2016) Andrea Mendoza Bertelli et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The development of a tissue-engineered tracheobronchial epithelial model using a bilayered collagen-hyaluronate scaffold

(2016) Cian O'Leary et al.   BIOMATERIALS

Towards 3D in vitro models for the study of cardiovascular tissues and disease

(2016) Alan J. Ryan et al.   DRUG DISCOVERY TODAY

Nanoparticle-mediated siRNA delivery assessed in a 3D co-culture model simulating prostate cancer bone metastasis

(2016) Kathleen A. Fitzgerald et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Life in 3D is never flat: 3D models to optimise drug delivery

(2015) Kathleen A. Fitzgerald et al.   JOURNAL OF CONTROLLED RELEASE

Comparison of 2D- and 3D-culture models as drug-testing platforms in breast cancer

(2015) YOSHINORI IMAMURA et al.   ONCOLOGY REPORTS

A Secreted Bacterial Protease Tailors the Staphylococcus aureus Virulence Repertoire to Modulate Bone Remodeling during Osteomyelitis

(2013) James E. Cassat et al.   Cell Host & Microbe

Understanding Metabolic Regulation and Its Influence on Cell Physiology

(2013) Christian M. Metallo et al.   MOLECULAR CELL

Adhesion, invasion and evasion: the many functions of the surface proteins of Staphylococcus aureus

(2013) Timothy J. Foster et al.   NATURE REVIEWS MICROBIOLOGY

Deconstructing the third dimension – how 3D culture microenvironments alter cellular cues

(2012) Brendon M. Baker et al.   JOURNAL OF CELL SCIENCE

Staphylococcus aureus protein A binding to osteoblast tumour necrosis factor receptor 1 results in activation of nuclear factor kappa B and release of interleukin-6 in bone infection

(2012) T. Claro et al.   MICROBIOLOGY-SGM

Staphylococcus aureus Protein A Plays a Critical Role in Mediating Bone Destruction and Bone Loss in Osteomyelitis

(2012) Amro Widaa et al.   PLoS One

Management of bone infections in adults: the surgeon's and microbiologist's perspectives

(2011) G. Mouzopoulos et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

Staphylococcus aureus Protein A Binds to Osteoblasts and Triggers Signals That Weaken Bone in Osteomyelitis

(2011) Tania Claro et al.   PLoS One

Substrate stiffness and contractile behaviour modulate the functional maturation of osteoblasts on a collagen–GAG scaffold

(2010) Michael B. Keogh et al.   Acta Biomaterialia

A novel collagen scaffold supports human osteogenesis—applications for bone tissue engineering

(2010) Michael B. Keogh et al.   CELL AND TISSUE RESEARCH

Degradation of fibrinogen and collagen by staphopains, cysteine proteases released from Staphylococcus aureus

(2010) T. Ohbayashi et al.   MICROBIOLOGY-SGM

Crosslinking and Mechanical Properties Significantly Influence Cell Attachment, Proliferation, and Migration Within Collagen Glycosaminoglycan Scaffolds

(2010) Matthew G. Haugh et al.   TISSUE ENGINEERING PART A

Novel Freeze-Drying Methods to Produce a Range of Collagen–Glycosaminoglycan Scaffolds with Tailored Mean Pore Sizes

(2009) Matthew G. Haugh et al.   TISSUE ENGINEERING PART C-METHODS

Animal Models for the Study of Osteomyelitis

(2009) Mitul Patel et al.   Seminars in Plastic Surgery

Microarchitecture of Three-Dimensional Scaffolds Influences Cell Migration Behavior via Junction Interactions

(2008) Brendan A.C. Harley et al.   BIOPHYSICAL JOURNAL

Normal Bone Anatomy and Physiology

(2008) B. Clarke   Clinical Journal of the American Society of Nephrology