Bilateral carotid artery stenosis causes unexpected early changes in brain extracellular matrix and blood-brain barrier integrity in mice

Mice deficient in endothelial α5 integrin are profoundly resistant to experimental ischemic stroke

(2016) Jill Roberts et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Appearance of claudin-5+ leukocytes in the central nervous system during neuroinflammation: a novel role for endothelial-derived extracellular vesicles

(2016) Debayon Paul et al.   Journal of Neuroinflammation

Resveratrol defends blood-brain barrier integrity in experimental autoimmune encephalomyelitis mice

(2016) Dong Wang et al.   JOURNAL OF NEUROPHYSIOLOGY

Substantial Reduction of Parenchymal Cerebral Blood Flow in Mice with Bilateral Common Carotid Artery Stenosis

(2016) Yorito Hattori et al.   Scientific Reports

Gliovascular Disruption and Cognitive Deficits in a Mouse Model with Features of Small Vessel Disease

(2015) Philip R Holland et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Microglial Activation with Reduction in Autophagy Limits White Matter Lesions and Improves Cognitive Defects During Cerebral Hypoperfusion

(2014) Zhao Yang et al.   CURRENT NEUROVASCULAR RESEARCH

Stepwise Recruitment of Transcellular and Paracellular Pathways Underlies Blood-Brain Barrier Breakdown in Stroke

(2014) Daniel Knowland et al.   NEURON

A radical scavenger edaravone inhibits matrix metalloproteinase-9 upregulation and blood–brain barrier breakdown in a mouse model of prolonged cerebral hypoperfusion

(2014) Nobukazu Miyamoto et al.   NEUROSCIENCE LETTERS

Apoptosis Signal–Regulating Kinase 1 Is a Novel Target Molecule for Cognitive Impairment Induced by Chronic Cerebral Hypoperfusion

(2013) Kensuke Toyama et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Blood-Brain Barrier Integrity and Glial Support: Mechanisms that can be Targeted for Novel Therapeutic Approaches in Stroke

(2012) Patrick T. Ronaldson et al.   CURRENT PHARMACEUTICAL DESIGN

An angiogenic role for the α5β1 integrin in promoting endothelial cell proliferation during cerebral hypoxia

(2012) Longxuan Li et al.   EXPERIMENTAL NEUROLOGY

Perlecan Domain V Induces VEGf Secretion in Brain Endothelial Cells through Integrin α5β1 and ERK-Dependent Signaling Pathways

(2012) Douglas N. Clarke et al.   PLoS One

Perlecan domain V is neuroprotective and proangiogenic following ischemic stroke in rodents

(2011) Boyeon Lee et al.   JOURNAL OF CLINICAL INVESTIGATION

Vascular Cognitive Impairment: Disease Mechanisms and Therapeutic Implications

(2011) Deborah A. Levine et al.   Neurotherapeutics

Do in vivo Experimental Models Reflect Human Cerebral Small Vessel Disease? a Systematic Review

(2008) Atticus H Hainsworth et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Intensity of chronic cerebral hypoperfusion determines white/gray matter injury and cognitive/motor dysfunction in mice

(2008) Kazunori Miki et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Direct labeling and visualization of blood vessels with lipophilic carbocyanine dye DiI

(2008) Yiwen Li et al.   Nature Protocols

The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders

(2008) Berislav V. Zlokovic   NEURON