Macrophage Migration Inhibitory Factor protects cancer cells from immunogenic cell death and impairs anti-tumor immune responses

Macrophage migration inhibitory factor (MIF) is induced by cytotoxic drugs and is involved in immune escape and migration in childhood rhabdomyosarcoma

(2016) Sarah Maria Johler et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Macrophage migration inhibitory factor enhances autophagy by regulating ROCK1 activity and contributes to the escape of dendritic cell surveillance in glioblastoma

(2016) Shugang Xu et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Macrophage migration inhibitory factor (MIF) is rendered enzymatically inactive by myeloperoxidase-derived oxidants but retains its immunomodulatory function

(2015) Nina Dickerhof et al.   FREE RADICAL BIOLOGY AND MEDICINE

Macrophage immigration inhibitory factor promotes cell proliferation and inhibits apoptosis of cervical adenocarcinoma

(2015) Peng Guo et al.   TUMOR BIOLOGY

Expression of Macrophage Migration Inhibitory Factor by Neuroblastoma Leads to the Inhibition of Antitumor T Cell Reactivity In Vivo

(2014) Q. Zhou et al.   JOURNAL OF IMMUNOLOGY

Cytotoxic T Lymphocytes Block Tumor Growth Both by Lytic Activity and IFN -Dependent Cell-Cycle Arrest

(2014) H. Matsushita et al.   Cancer Immunology Research

Functional disruption of macrophage migration inhibitory factor (MIF) suppresses proliferation of human H460 lung cancer cells by caspase-dependent apoptosis

(2013) Yubiao Guo et al.   Cancer Cell International

Inducers of immunogenic cancer cell death

(2013) Aleksandra M. Dudek et al.   CYTOKINE & GROWTH FACTOR REVIEWS

T-helper-1-cell cytokines drive cancer into senescence

(2013) Heidi Braumüller et al.   NATURE

MIF deficiency does not alter glucose homeostasis or adipose tissue inflammatory cell infiltrates during diet-induced obesity

(2013) Sarah J. Conine et al.   Obesity

Immunogenic Cell Death in Cancer Therapy

(2012) Guido Kroemer et al.   Annual Review of Immunology

Macrophage Migration Inhibitory Factor Promotes Tumor Growth and Metastasis by Inducing Myeloid-Derived Suppressor Cells in the Tumor Microenvironment

(2012) K. D. Simpson et al.   JOURNAL OF IMMUNOLOGY

Hypericin-based photodynamic therapy induces surface exposure of damage-associated molecular patterns like HSP70 and calreticulin

(2011) Abhishek D. Garg et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Human Tumor Cells Killed by Anthracyclines Induce a Tumor-Specific Immune Response

(2011) J. Fucikova et al.   CANCER RESEARCH

Serum macrophage migration-inhibitory factor as a diagnostic and prognostic biomarker for gastric cancer

(2009) Harry Hua-Xiang Xia et al.   CANCER

Novel Subset of CD8 + Dendritic Cells Localized in the Marginal Zone Is Responsible for Tolerance to Cell-Associated Antigens

(2009) C.-H. Qiu et al.   JOURNAL OF IMMUNOLOGY

Lessons in Signaling and Tumorigenesis from Polyomavirus Middle T Antigen

(2009) M. M. Fluck et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

A Tautomerase-Null Macrophage Migration-Inhibitory Factor (MIF) Gene Knock-In Mouse Model Reveals That Protein Interactions and Not Enzymatic Activity Mediate MIF-Dependent Growth Regulation

(2009) G. Fingerle-Rowson et al.   MOLECULAR AND CELLULAR BIOLOGY

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors

(2009) François Ghiringhelli et al.   NATURE MEDICINE

Induction of Immunological Tolerance by Apoptotic Cells Requires Caspase-Dependent Oxidation of High-Mobility Group Box-1 Protein

(2008) Hirotaka Kazama et al.   IMMUNITY