Article
Environmental Sciences
Mulatu Yohannes Nanusha, Martin Krauss, Bettina Gro Sorensen, Tobias Schulze, Bjarne W. Strobel, Werner Brack
Summary: This study utilized liquid chromatography coupled to high resolution mass spectrometry to detect 27 toxic secondary plant metabolites in three Danish rivers, including 12 compounds that have not been reported before.
ENVIRONMENTAL SCIENCES EUROPE
(2021)
Article
Microbiology
Nivethika Ajeethan, Shawkat Ali, Keith D. D. Fuller, Lord Abbey, Svetlana N. N. Yurgel
Summary: The apple sector dominates the tree fruit industry in Nova Scotia, Canada. However, it faces challenges such as apple replant disease (ARD). This study used amplicon sequencing to compare the microbiomes of cultivated apple orchard soil, uncultivated soil, and apple roots. The results showed significant differences in microbial community between cultivated and uncultivated soil, with an increase in potential pathogens in the orchard soil. On the other hand, certain beneficial microorganisms and non-fungal eukaryotes were more abundant in the orchard soil, and potential plant-growth-promoting (PGP) bacteria were found in apple roots.
Review
Food Science & Technology
Dan Xu, Mengyao Xue, Zhen Shen, Xiaowei Jia, Xuwen Hou, Daowan Lai, Ligang Zhou
Summary: Fungal phytotoxic secondary metabolites are toxic substances produced by fungi through biochemical reactions, with a high level of diversity in their properties. These metabolites are mainly isolated from phytopathogenic fungal species, with aromatic polyketides and sesquiterpenoids being the main phytotoxic compounds.
Review
Biochemistry & Molecular Biology
Sajad Fakhri, Sadaf Abdian, Seyede Nazanin Zarneshan, Esra Kuepeli Akkol, Mohammad Hosein Farzaei, Eduardo Sobarzo-Sanchez
Summary: This review addresses the dysregulated pathways in Parkinson's disease (PD) and proposes the use of plant secondary metabolites to modulate PD-related manifestations, particularly by targeting mitochondria.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Microbiology
Zareen Narayanan, Bernard R. Glick
Summary: There is a growing interest in using beneficial microorganisms as alternatives to chemical or plant-derived molecules for producing therapeutic agents. Bacterial endophytes, which are plant-associated microorganisms, can synthesize a wide range of secondary metabolites with unique chemical structures that have anti-microbial, antiviral, anti-cancer, and anti-inflammatory properties. The production of these bioactive compounds can also benefit the host plant.
Article
Microbiology
Tom P. P. Pielhop, Carolin Popp, Sebastian Fricke, Dennis Knierim, Paolo Margaria, Edgar Maiss
Summary: Since 2009, at least ten additional viruses have been identified and assigned to the Alternaviridae virus family. This study reports two new mycoviruses assigned to this family, which were isolated from apple roots affected by apple replant disease (ARD). The first alternavirus, named DtAV1, was found in a Dactylonectria torresensis isolate, while the second virus, named IrAV1, was found in an isolate of Ilyonectria robusta. Full genomic sequences of the viruses were determined and analyzed. This study provides new insights into the virome of ARD-associated fungi and enhances our understanding of the disease complexity.
ARCHIVES OF MICROBIOLOGY
(2023)
Article
Chemistry, Organic
Rui Yang, Xingchun Sun, Yunqin Zhang, Guozhi Xiao
Summary: Efficient and collective synthesis of rhynchosporosides, which cause scald diseases, has been achieved through an orthogonal one-pot glycosylation strategy based on PTFAI glycosylation, Yu glycosylation, and PVB glycosylation. This strategy incorporates reagent modulation and remote anchimeric assistance (RMRAA) alpha-glucosylation strategies, overcoming issues encountered in thioglycoside-based orthogonal one-pot glycosylation and streamlining glycan chemical synthesis.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2022)
Review
Plant Sciences
Soo-In Sohn, Subramani Pandian, Kasinathan Rakkammal, Muthiah Joe Virgin Largia, Senthil Kumar Thamilarasan, Sekaran Balaji, Yedomon Ange Bovys Zoclanclounon, Jayabalan Shilpha, Manikandan Ramesh
Summary: Secondary metabolites are important specialized molecules with proven health-promoting effects on humans. Exogenous jasmonates (JAs) have been recognized for their ability to trigger plant growth and development and can also effectively elicit the synthesis of secondary metabolites. However, large-scale production of these metabolites is limited, but advancements in plant cell culture technology and synthetic biology offer potential avenues for overcoming this limitation.
FRONTIERS IN PLANT SCIENCE
(2022)
Review
Biochemistry & Molecular Biology
Ali Movahedi, Amir Almasi Zadeh Yaghuti, Hui Wei, Paul Rutland, Weibo Sun, Mohaddeseh Mousavi, Dawei Li, Zhuge Qiang
Summary: Populus trees face continuous environmental challenges throughout their life cycle, exhibiting various defenses including the production of secondary metabolites. While many of these metabolites have been functionally described, their overall functions are still not fully understood. Research indicates therapeutic effects and leads to further study of secondary metabolites and their biosynthesis in Populus.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Microbiology
Gustavo A. Diaz-Cruz, Jingyu Liu, Kapil Tahlan, Dawn R. D. Bignell
Summary: Streptomyces bacteria are important sources of microbial specialized metabolites with applications in medicine and agriculture. Some species are plant pathogens, causing diseases such as potato scab. The highly pathogenic strain Streptomyces sp. 11-1-2 produces nigericin and geldanamycin, which can cause damage to plant tissues.
MICROBIOLOGY SPECTRUM
(2022)
Review
Microbiology
Zhaogao Li, Weie Wen, Ming Qin, Yuqi He, Delin Xu, Lin Li
Summary: This review summarizes the research progress on the interactions between endophytes and hosts, including their effects on the growth and development of host plants, physiological stress, and synthesis of new compounds. The review also discusses the positive effects of multiomics analysis on these interactions and the potential applications and development prospects of metabolites synthesized through symbiotic interactions.
FRONTIERS IN MICROBIOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Ilaria Chiocchio, Manuela Mandrone, Paola Tomasi, Lorenzo Marincich, Ferruccio Poli
Summary: Plant wastes contain valuable secondary metabolites that have wide applications in healthcare and food industries; however, the potential of plant secondary metabolites for other uses requires further research and exploration.
Article
Biochemistry & Molecular Biology
Roman G. Zenkov, Kirill Kirsanov, Anna M. Ogloblina, Olga A. Vlasova, Denis S. Naberezhnov, Natalia Y. Karpechenko, Timur Fetisov, Ekaterina A. Lesovaya, Gennady A. Belitsky, Nina G. Dolinnaya, Marianna G. Yakubovskaya
Summary: Guanine-rich DNA sequences tend to adopt noncanonical G-quadruplex structures, and these sequences are over-represented in oncogene promoter regions. Plant secondary metabolites (PSMs) interact with G-quadruplexes and influence gene expression by modulating cell signaling pathways.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Plant Sciences
Anna Koprivova, Stanislav Kopriva
Summary: Plants communicate with microorganisms through metabolites exuded from roots, which play a crucial role in modulating the functions of plant associated microbiota. Recent research has identified various metabolites involved in this communication network, but there are still significant knowledge gaps to be filled in future studies.
CURRENT OPINION IN PLANT BIOLOGY
(2022)
Article
Soil Science
Tracey S. Somera, Shiri Freilich, Mark Mazzola
Summary: The interaction between rootstock and seed meal plays a significant role in shaping the bacterial, fungal, and oomycete communities within the apple rhizosphere, contributing to effective disease control and potential long-term benefits for orchard soil health.
APPLIED SOIL ECOLOGY
(2021)
Article
Microbiology
L. M. Manici, M. L. Sacca, M. Lodesani
CURRENT MICROBIOLOGY
(2020)
Article
Agriculture, Multidisciplinary
L. M. Manici, F. Caputo, G. A. Cappelli, E. Ceotto
Summary: The study found that repeated soil amendment with digestate significantly increased the soil's capacity to support plant growth over two years, and reduced the risk of plant root infection by soil-borne pathogens. The higher abundance of Pseudomonas and actinomycetes in digestate-amended soils suggests that these bacteria are involved in enhancing the soil's natural ability to control soil-borne pathogens.
RENEWABLE AGRICULTURE AND FOOD SYSTEMS
(2021)
Article
Agronomy
L. M. Manici, E. Caboni, F. Caputo, A. Frattarelli, S. Lucioli
Summary: Research indicates that the extracellular compounds of Dactylonectria torresensis have phytotoxic effects on grapevine, apple, and peach rootstocks, inhibiting plant growth. Analysis also reveals the presence of various bioactive compounds in the culture filtrates of two D. torresensis isolates from apple roots.
Article
Green & Sustainable Science & Technology
Sebastian Soppelsa, Luisa Maria Manici, Francesco Caputo, Massimo Zago, Markus Kelderer
Summary: The study found that waste-derived biomasses are a promising eco-friendly option for counteracting strawberry yield decline. However, careful evaluation of composition, doses, and application times is required to reduce potential phytotoxic effects.
Article
Biophysics
Taynara Tuany Borges Valeriano, Glauco de Souza Rolim, Luisa Maria Manici, Laura Giustarini, Simone Bregaglio
Summary: Forecasting the severity of plant diseases is crucial for farmers and companies to optimize management actions and predict crop yields. A new simulation model called ARISE was developed to formalize the key phases of the life cycle of Puccinia kuenhii, the causal agent of orange rust on sugarcane, and it performed well in calibration and evaluation, accurately matching observations of orange rust severity. Further improvements will involve coupling ARISE with a sugarcane growth model to assess yield losses and develop a decision support system for sugarcane growers.
INTERNATIONAL JOURNAL OF BIOMETEOROLOGY
(2021)
Article
Microbiology
Maria Ludovica Sacca, Luisa Maria Manici
Summary: Honey bee-associated bacteria are a potential source of natural compounds for controlling hive decline. A gene-based approach was used to investigate biosynthetic genes in bacteria living on honey bees, leading to the identification of functional genes involved in the production of bioactive compounds. The findings suggest that microbial populations in apiaries harbor genes that can help reduce important honey bee pathogens.
MICROBIOLOGICAL RESEARCH
(2021)
Article
Microbiology
Maria Ludovica Sacca, Giulia Bianchi, Roberto Lo Scalzo
Summary: Beehives are inhabited by bacteria that can produce bioactive metabolites such as 2-heptanone, which has protective properties against honey bee pathogens and can potentially be used for pest management. This study identified several bacterial species associated with honey bees capable of producing 2-heptanone and found putative protein homologs involved in its biosynthesis in different bacterial strains. The production of 2-heptanone by specific bacteria suggests a role in microbial relationships within hives and warrants further investigation into its biosynthetic potential in apiaries.
Article
Agronomy
Luisa Maria Manici, Maria Ludovica Sacca, Carla Scotti, Francesco Caputo
Summary: This study revealed that bacterial communities in kiwifruit orchards with declining yields were significantly reduced and modified, which may contribute to the decreased ability of soil to support plant growth. Furthermore, kiwifruit had a long-lasting effect on soilborne fungal communities, including root endophytes.
Article
Agronomy
Luisa M. Manici, F. Caputo, M. Castellini, M. L. Sacca
Summary: The purpose of this study was to investigate the relationship between Binucleate Rhizoctonia sp. (BNR) and olive trees in order to find beneficial soil microorganisms suitable for supporting plant growth in degraded semi-arid soils. BNR was isolated from ancient olive groves and its functional relationship with olive trees was estimated using growth assays. The results showed that BNR AG-A increased olive tree growth and promoted the production of indole-3-acetic acid, suggesting its potential as a biotic resource for enhancing soil ecosystem services.
Article
Biodiversity Conservation
Luisa M. Manici, Isabella De Meo, Maria Ludovica Sacca, Enrico Ceotto, Francesco Caputo, Alessandro Paletto
Summary: This study investigated the changes in fungal community of deadwood based on the host plants and wood degradation levels. The results showed that the composition of wood colonizing fungal communities varied depending on the host plants and wood decay. White rot fungal species were dominant in black locust and poplar, while lignin-degrading ascomycete Daldinia chilidiae colonized willow along with fungi associated with tree dieback.
ECOLOGICAL INDICATORS
(2023)
Article
Agriculture, Multidisciplinary
A. Assirelli, F. Fornasier, F. Caputo, L. M. Manici
Summary: Composting technologies have advanced alongside the increased interest in recycling organic waste. However, in-field compost application requires further technical improvement and experience to optimize its effectiveness in different agro-environments and types of crops. Precision agricultural machinery and limiting soil incorporation depth were used to assess biological soil features after compost application.
RENEWABLE AGRICULTURE AND FOOD SYSTEMS
(2023)