4.6 Article

The dynamics of spiral tip adjacent to inhomogeneity in cardiac tissue

期刊

出版社

ELSEVIER SCIENCE BV
DOI: 10.1016/j.physa.2017.09.051

关键词

Spiral wave; Cardiac tissue; Inhomogeneity

资金

  1. Fundamental Research Funds for the Central Universities of China [2015XKMS080]

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Rotating spiral waves in cardiac tissue are implicated in life threatening cardiac arrhythmias. Experimental and theoretical evidences suggest the inhomogeneities in cardiac tissue play a significant role in the dynamics of spiral waves. Based on a modified 2D cardiac tissue model, the interaction of inhomogeneity on the nearby rigidly rotating spiral wave is numerically studied. The adjacent area of the inhomogeneity is divided to two areas, when the initial rotating center of the spiral tip is located in the two areas, the spiral tip will be attracted and anchor on the inhomogeneity finally, or be repulsed away. The width of the area is significantly dependent on the intensity and size of the inhomogeneity. Our numerical study sheds some light on the mechanism of the interaction of inhomogeneity on the spiral wave in cardiac tissue. (c) 2017 Elsevier B.V. All rights reserved.

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