期刊
PHARMACOLOGY & THERAPEUTICS
卷 181, 期 -, 页码 183-196出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.pharmthera.2017.08.003
关键词
FOX family; Drug resistance; Stern cell; Cancer; Drug target; FOXM1
资金
- National Natural Science Foundation of China [81573454]
- Beijing Natural Science Foundation [7172142]
- CAMS Innovation Fund for Medical Sciences [2016-I2M-3-007]
FOX families play important roles in biological processes, including metabolism, development, differentiation, proliferation, apoptosis, migration, invasion and longevity. Here we are focusing on roles of FOX members in cancers, FOX members and drug resistance, FOX members and stem cells. Finally, FOX members as drug targets of cancer treatment were discussed. Future perspectives of FOXC1 research were described in the end.
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