The efficiency of lipid nanoparticles with an original cationic lipid as a siRNA delivery system for macrophages and dendritic cells

Therapeutic miRNA and siRNA: Moving from Bench to Clinic as Next Generation Medicine

(2017) Chiranjib Chakraborty et al.   Molecular Therapy-Nucleic Acids

Therapeutic nucleic acids: current clinical status

(2016) Kannan Sridharan et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Nanoparticle-Delivered IRF5 siRNA Facilitates M1 to M2 Transition, Reduces Demyelination and Neurofilament Loss, and Promotes Functional Recovery After Spinal Cord Injury in Mice

(2016) Jun Li et al.   INFLAMMATION

Manipulating the NF-κB pathway in macrophages using mannosylated, siRNA-delivering nanoparticles can induce immunostimulatory and tumor cytotoxic functions

(2016) Ryan Ortega et al.   International Journal of Nanomedicine

Peritoneal Macrophage-Specific TNF-α Gene Silencing in LPS-Induced Acute Inflammation Model Using CD44 Targeting Hyaluronic Acid Nanoparticles

(2016) Verbena Y. Kosovrasti et al.   MOLECULAR PHARMACEUTICS

Role of tumor-associated macrophages in human malignancies: friend or foe?

(2016) Motohiro Takeya et al.   PATHOLOGY INTERNATIONAL

Preclinical and clinical development of siRNA-based therapeutics

(2015) Gulnihal Ozcan et al.   ADVANCED DRUG DELIVERY REVIEWS

Role of dendritic cells in the initiation, progress and modulation of systemic autoimmune diseases

(2015) Juan Pablo Mackern-Oberti et al.   AUTOIMMUNITY REVIEWS

Lipid-Based Nanocarriers for RNA Delivery

(2015) Hui Xue et al.   CURRENT PHARMACEUTICAL DESIGN

Silencing collapsin response mediator protein-2 reprograms macrophage phenotype and improves infarct healing in experimental myocardial infarction model

(2015) Long-Shu Zhou et al.   Journal of Inflammation-London

In Vivo Silencing of the Transcription Factor IRF5 Reprograms the Macrophage Phenotype and Improves Infarct Healing

(2013) Gabriel Courties et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

In Vitro Generation of Monocyte-Derived Macrophages under Serum-Free Conditions Improves Their Tumor Promoting Functions

(2012) Flora Rey-Giraud et al.   PLoS One

Systemic RNAi-mediated Gene Silencing in Nonhuman Primate and Rodent Myeloid Cells

(2012) Tatiana I Novobrantseva et al.   Molecular Therapy-Nucleic Acids

Influence of Cationic Lipid Composition on Gene Silencing Properties of Lipid Nanoparticle Formulations of siRNA in Antigen-Presenting Cells

(2011) Genc Basha et al.   MOLECULAR THERAPY

Therapeutic siRNA silencing in inflammatory monocytes in mice

(2011) Florian Leuschner et al.   NATURE BIOTECHNOLOGY

siRNA silencing of PD-L1 and PD-L2 on dendritic cells augments expansion and function of minor histocompatibility antigen-specific CD8+ T cells

(2010) W. Hobo et al.   BLOOD

Treatment of Autoimmune Arthritis Using RNA Interference-Modulated Dendritic Cells

(2010) X. Zheng et al.   JOURNAL OF IMMUNOLOGY

A Nanoparticle System Specifically Designed to Deliver Short Interfering RNA Inhibits Tumor Growth In vivo

(2009) N. Yagi et al.   CANCER RESEARCH

Fusogenic activity of cationic lipids and lipid shape distribution

(2009) Caroline Lonez et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

RNAi-based therapeutics-current status, challenges and prospects

(2009) Katrin Tiemann et al.   EMBO Molecular Medicine

Correlation of mRNA and protein in complex biological samples

(2009) Tobias Maier et al.   FEBS LETTERS

Regulation of interferon and Toll-like receptor signaling during macrophage activation by opposing feedforward and feedback inhibition mechanisms

(2009) Xiaoyu Hu et al.   IMMUNOLOGICAL REVIEWS

Targeted Delivery of Small Interfering RNA to Human Dendritic Cells To Suppress Dengue Virus Infection and Associated Proinflammatory Cytokine Production

(2009) S. Subramanya et al.   JOURNAL OF VIROLOGY

RNAi-mediated CCR5 Silencing by LFA-1-targeted Nanoparticles Prevents HIV Infection in BLT Mice

(2009) Sang-Soo Kim et al.   MOLECULAR THERAPY

Knocking down barriers: advances in siRNA delivery

(2009) Kathryn A. Whitehead et al.   NATURE REVIEWS DRUG DISCOVERY

T Cell-Specific siRNA Delivery Suppresses HIV-1 Infection in Humanized Mice

(2008) Priti Kumar et al.   CELL

A combinatorial library of lipid-like materials for delivery of RNAi therapeutics

(2008) Akin Akinc et al.   NATURE BIOTECHNOLOGY

Systemic Leukocyte-Directed siRNA Delivery Revealing Cyclin D1 as an Anti-Inflammatory Target

(2008) D. Peer et al.   SCIENCE

Inhibition of tumor necrosis factor alpha secretion in rat Kupffer cells by siRNA: In vivo efficacy of siRNA-liposomes

(2007) Yawu Jing et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS