Article
Urology & Nephrology
Rikako Oki, Yoshifumi Hamasaki, Yohei Komaru, Yoshihisa Miyamoto, Ryo Matsuura, Daisuke Yamada, Masao Iwagami, Kent Doi, Haruki Kume, Masaomi Nangaku
Summary: A retrospective study of 148 PD patients found that the CDP group had significantly higher PD catheter survival rates compared to the non-CDP group and virtual discontinuation group. CDP may be an effective and less invasive surgical treatment for ESI/TI to improve PD catheter survival.
KIDNEY INTERNATIONAL REPORTS
(2021)
Review
Urology & Nephrology
Antonio Scalamogna, Luca Nardelli, Giuseppe Castellano
Summary: Peritoneal dialysis-related infections, particularly catheter-related infections, are a significant complication leading to technical failure in patients on peritoneal dialysis. Recent research suggests that exit-site/tunnel infections contribute to peritonitis and catheter loss. Mini-invasive surgical techniques have been proposed as successful rescue treatments for refractory infections before considering catheter removal.
JOURNAL OF NEPHROLOGY
(2023)
Article
Infectious Diseases
Edyta Golembiewska, Kazimierz Ciechanowski
Summary: This case report highlights the development of ESI on a polycythemia vera skin lesion in a PD patient, suggesting that skin manifestations of PV may predispose patients to ESI.
BMC INFECTIOUS DISEASES
(2021)
Article
Nursing
Xiao-rong Ding, Hui-e Huang, Yu-mei Liao, Jin-rong Zhu, Wen Tang, Xiao-wan Fang, Chun-yan Su
Summary: The study investigated practice patterns in exit-site care for peritoneal dialysis patients and identified risk factors for exit-site infection. Adherence levels varied among patients in different aspects of care, and self-care behaviors were correlated with exit-site status.
JOURNAL OF ADVANCED NURSING
(2021)
Review
Hematology
Moniyka Sachar, Ankur Shah
Summary: Exit site infection (ESI) is a common complication of peritoneal dialysis (PD) and is associated with a high risk of catheter removal and peritonitis. The type of bacteria causing ESI affects the risk of subsequent peritonitis, with gram-positive ESIs having a lower cure rate. Mycobacteria, Staphylococcus aureus, and Pseudomonas aeruginosa are the most common bacteria causing ESI requiring catheter removal. No specific prophylactic measures have shown clear benefits, and individualized exit site hygiene is recommended. Topical gentamicin has been found effective in preventing most ESIs, especially gram-negative ESIs.
THERAPEUTIC APHERESIS AND DIALYSIS
(2022)
Article
Medicine, General & Internal
Jose Luis Cobo-Sanchez, Ian Blanco-Mavillard, Raquel Pelayo-Alonso, Noelia Mancebo-Salas, Ismael Fernandez-Fernandez, Joan Ernest De Pedro-Gomez
Summary: The EXITA study aims to develop and validate an instrument for early detection of exit site infections in haemodialysis patients with central venous catheters. The study involves a multicentre prospective cohort with a sample size of 457 patients, and will use logistic regression analysis to validate the proposed scale.
Article
Urology & Nephrology
Mariane Rigo, Roberto Pecoits-Filho, Mark Lambie, Felipe Francisco Tuon, Pasqual Barretti, Thyago Proenca de Moraes
Summary: The study found that there is a correlation between the diagnosis of ESI with a score based on five clinical signs obtained from ES inspection, with differences according to the patient's race. Using scales for the diagnosis of ESI does not add much information in addition to the presence of purulent secretion as currently recommended by the ISPD.
PERITONEAL DIALYSIS INTERNATIONAL
(2021)
Article
Urology & Nephrology
Lila Moghiseh, Monir Nobahar, Raheb Ghorbani, Shiva Sirafian
Summary: This study aimed to investigate the effect of propolis on the incidence of catheter exit site infection and peritonitis in peritoneal dialysis patients. The results showed that the intervention group using propolis had lower rates of catheter exit site infection and peritonitis compared to the control and placebo groups, with no significant differences observed among the three groups.
Article
Urology & Nephrology
Christy W. H. Au, Desmond Y. H. Yap, Jasper F. W. Chan, Terence P. S. Yip, Tak M. Chan
Summary: The study showed that catheter-related infections of Serratia species in PD patients have low risk of progressing to peritonitis and favorable response to medical therapy, while Serratia peritonitis is associated with high rates of catheter removal and peritoneal failure.
Article
Urology & Nephrology
Hiroki Yabe, Keiko Okada, Kenichi Kono, Yuto Imoto, Ayaka Onoyama, Sayaka Ito, Yoshifumi Moriyama, Hirotake Kasuga, Yasuhiko Ito
Summary: The study aims to examine the effectiveness of assisted peritoneal dialysis (PD) in preventing exit-site infections in older patients. The results show that even in the absence of cognitive impairment, older patients who do not receive assistance for exit-site care are at a higher risk of developing exit-site infections.
CLINICAL AND EXPERIMENTAL NEPHROLOGY
(2022)
Article
Urology & Nephrology
Luca Nardelli, Antonio Scalamogna, Piergiorgio Messa
Summary: In a study analyzing infective episodes in 123 CAPD patients, positioning the superficial cuff subcutaneously at least 4 cm internal to the exit-site significantly reduced cuff colonization by bacteria, leading to decreased exit site infections, tunnel infections, and peritonitis.
JOURNAL OF NEPHROLOGY
(2021)
Article
Urology & Nephrology
Hila Soetendorp, Orit Kliuk-Ben Bassat, Asaf Wasserman, Doron Schwartz, Rachila Bedbalayev, Inna Faukman, Ayelet Grupper
Summary: This study aimed to evaluate infections in PD patients after changing exit-site policy, finding that the adjusted care significantly reduced ESI incidence, potentially by avoiding water exposure and lessening bacterial colonization.
CLINICAL NEPHROLOGY
(2021)
Article
Urology & Nephrology
Htay Htay, Jason Chon Jun Choo, David W. Johnson, Elaine M. Pascoe, Mathini Jayaballa, Elizabeth Ley Oei, Li Choo Ng, Sin Yan Wu, Marjorie Wai Yin Foo
Summary: Weekly chlorhexidine dressing in PD patients showed good infection prevention outcomes and high patient acceptance, despite a 12% rate of localized contact dermatitis.
INTERNATIONAL UROLOGY AND NEPHROLOGY
(2021)
Article
Multidisciplinary Sciences
Haruna Fukuzaki, Junichiro Nakata, Shuko Nojiri, Yuki Shimizu, Toshiki Kano, Yuka Shirotani, Takuya Maeda, Nao Nohara, Hiroaki Io, Yusuke Suzuki
Summary: The study demonstrates that negative-pressure wound therapy (NPWT) can effectively reduce exit-site scores in the early postoperative period for PD catheter exit-site management, without significant delay in the occurrence of catheter-related infections (CRIs) and peritonitis.
SCIENTIFIC REPORTS
(2022)
Review
Urology & Nephrology
Luca Nardelli, Antonio Scalamogna, Giuseppe Castellano
Summary: Peritoneal dialysis-related infections are a major cause of morbidity and mortality in PD patients. Exit-site and tunnel infections are believed to play a direct role in causing peritonitis. Ultrasound examination is a simple, rapid, non-invasive and widely available method for evaluating PD catheter-related infections. It has higher sensitivity in diagnosing simultaneous tunnel infection compared to physical examination alone and provides important prognostic information. However, there is no evidence of its usefulness as a screening tool for early diagnosis of tunnel infections in asymptomatic PD patients.
JOURNAL OF NEPHROLOGY
(2023)