期刊
PEDIATRIC AND DEVELOPMENTAL PATHOLOGY
卷 21, 期 6, 页码 537-547出版社
SAGE PUBLICATIONS INC
DOI: 10.1177/1093526618770318
关键词
adolescents; cord coiling; iron deficiency; multiple gestations
资金
- National Research Initiative or Agriculture and Food Research Initiative of the United States Department of Agriculture National Institute of Food and Agriculture [2005-35200, 2008-01857]
- Gerber Foundation
Abnormal umbilical cord coiling has been associated with adverse neonatal outcomes, but the etiology of these findings remains poorly characterized. This study was undertaken to examine associations between cord coiling and maternal iron (Fe) status and to identify potential determinants of hypo- and hypercoiling in 2 higher risk obstetric groups: pregnant adolescents (<= 18 years, n = 92) and adult women carrying twins (n = 49), triplets (n = 11), or quadruplets (n = 1). Umbilical cords were classified as hypo-, normo-, or hypercoiled using digital photographs to assess gross appearance. Hypocoiling and hypercoiling were observed in 44% (n = 86/195) and 13% (n = 26/195) of the combined study population. The prevalence of hypocoiling among women carrying multiples was over 3-fold higher than the prevalence in singleton pregnancies based on the published data. Within the entire study population, hypocoiling was associated with a lower gestational age at birth when compared to normocoiling and hypercoiling (36.3 +/- 3.6 weeks [n = 86] vs 37.8 +/- 2.7 [n = 83], P < .01, and 38.2 +/- 2.6 [n = 26], P < .01, respectively), whereas hypercoiling was associated with significantly lower serum ferritin when compared to normocoiling (P < .01) and hypocoiling (P < .001). In the multiples cohort only, hypercoiling was significantly associated with multiparity (P < .01) and lower birth weight (P < .05). Further studies are needed to identify the determinants and consequences of cord coiling.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据