Susceptibility of promastigotes and intracellular amastigotes from distinct Leishmania species to the calpain inhibitor MDL28170

Safety and efficacy of current alternatives in the topical treatment of cutaneous leishmaniasis: a systematic review

(2017) PRISCILA WOLF NASSIF et al.   PARASITOLOGY

The potent cell permeable calpain inhibitor MDL28170 affects the interaction of Leishmania amazonensis with macrophages and shows anti-amastigote activity

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Visceral leishmaniasis: Revisiting current treatments and approaches for future discoveries

(2016) Joo Hwan No   ACTA TROPICA

Application of a non-hazardous vital dye for cell counting with automated cell counters

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Calpain research for drug discovery: challenges and potential

(2016) Yasuko Ono et al.   NATURE REVIEWS DRUG DISCOVERY

Why calpain inhibitors are interesting leading compounds to search for new therapeutic options to treat leishmaniasis?

(2016) VITOR ENNES-VIDAL et al.   PARASITOLOGY

Lipophosphoglycans from Leishmania amazonensis Strains Display Immunomodulatory Properties via TLR4 and Do Not Affect Sand Fly Infection

(2016) Paula M. Nogueira et al.   PLoS Neglected Tropical Diseases

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(2015) Ines Kevric et al.   DERMATOLOGIC CLINICS

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(2015) Dianella Savoia   Journal of Infection in Developing Countries

Advances in Development of New Treatment for Leishmaniasis

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The Calpain Inhibitor MDL28170 Induces the Expression of Apoptotic Markers in Leishmania amazonensis Promastigotes

(2014) Fernanda A. Marinho et al.   PLoS One

Calpains: Potential Targets for Alternative Chemotherapeutic Intervention Against Human Pathogenic Trypanosomatids

(2013) M. Branquinha et al.   CURRENT MEDICINAL CHEMISTRY

High Content Analysis of Primary Macrophages Hosting Proliferating Leishmania Amastigotes: Application to Anti-leishmanial Drug Discovery

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Validation of a simple resazurin-based promastigote assay for the routine monitoring of miltefosine susceptibility in clinical isolates of Leishmania donovani

(2012) Arpita Kulshrestha et al.   PARASITOLOGY RESEARCH

Calpains — An elaborate proteolytic system

(2011) Yasuko Ono et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

MDL28170, a Calpain Inhibitor, Affects Trypanosoma cruzi Metacyclogenesis, Ultrastructure and Attachment to Rhodnius prolixus Midgut

(2011) Vítor Ennes-Vidal et al.   PLoS One

Effects of the calpain inhibitor MDL28170 on the clinically relevant forms of Trypanosoma cruzi in vitro

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Evaluation of hydrogen peroxide-based disinfectants in a new resazurin microplate method for rapid efficacy testing of biocides

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Arrested growth of Trypanosoma cruzi by the calpain inhibitor MDL28170 and detection of calpain homologues in epimastigote forms

(2009) L. S. SANGENITO et al.   PARASITOLOGY

HIV Aspartyl Peptidase Inhibitors Interfere with Cellular Proliferation, Ultrastructure and Macrophage Infection of Leishmania amazonensis

(2009) Lívia O. Santos et al.   PLoS One

Phenotypic non-equivalence of murine (monocyte-) macrophage cells in biomaterial and inflammatory models

(2008) Lisa M. Chamberlain et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A