期刊
ORGANIC LETTERS
卷 20, 期 5, 页码 1444-1447出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.8b00228
关键词
-
资金
- ENSCM (Ecole Nationale Superieure de Chimie de Montpellier)
The synthesis of cyclic imidazolidines via two N-C bond-forming sequences has been developed. The transformation goes through a (3 + 2)-cycloaddition reaction in the presence of catalytic amounts of palladium by combining several vinyl aziridines and cyclic N-sulfonyl imines. Interestingly, the use of LiCl as additive allowed the improvement of diastereoselectivities when less encumbered substrates were used. The imidazolidine derivatives that bear aminal cores are isolated in high yields (15 examples, up to 96% yield) and diastereoselectivities (up to >20:1).
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据