The role of primary cilia in corpus callosum formation is mediated by production of the Gli3 repressor

The ciliogenic transcription factor Rfx3 is required for the formation of the thalamocortical tract by regulating the patterning of prethalamus and ventral telencephalon

(2015) Dario Magnani et al.   HUMAN MOLECULAR GENETICS

Clinical, genetic and imaging findings identify new causes for corpus callosum development syndromes

(2014) Timothy J. Edwards et al.   BRAIN

New insights into genotype–phenotype correlation for GLI3 mutations

(2014) Florence Démurger et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Evolution and development of interhemispheric connections in the vertebrate forebrain

(2014) Rodrigo Suárez et al.   Frontiers in Human Neuroscience

CNS involvement in OFD1 syndrome: a clinical, molecular, and neuroimaging study

(2014) Ennio Del Giudice et al.   Orphanet Journal of Rare Diseases

A de novoGLI3mutation in a patient with acrocallosal syndrome

(2013) Leonie Speksnijder et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

The Ciliary G-Protein-Coupled Receptor Gpr161 Negatively Regulates the Sonic Hedgehog Pathway via cAMP Signaling

(2013) Saikat Mukhopadhyay et al.   CELL

Gli3 is required in Emx1+ progenitors for the development of the corpus callosum

(2013) Eleni-Maria Amaniti et al.   DEVELOPMENTAL BIOLOGY

C5orf42 is the major gene responsible for OFD syndrome type VI

(2013) Estelle Lopez et al.   HUMAN GENETICS

Variable expressivity of ciliopathy neurological phenotypes that encompass Meckel–Gruber syndrome and Joubert syndrome is caused by complex de-regulated ciliogenesis, Shh and Wnt signalling defects

(2013) Zakia A. Abdelhamed et al.   HUMAN MOLECULAR GENETICS

The Ciliary Protein Ftm Is Required for Ventricular Wall and Septal Development

(2013) Christoph Gerhardt et al.   PLoS One

Gli3 Controls Corpus Callosum Formation by Positioning Midline Guideposts During Telencephalic Patterning

(2012) Dario Magnani et al.   CEREBRAL CORTEX

The in vivo dissection of direct RFX-target gene promoters in C. elegans reveals a novel cis-regulatory element, the C-box

(2012) Jan Burghoorn et al.   DEVELOPMENTAL BIOLOGY

Hippocampal commissure defects in crosses of four inbred mouse strains with absent corpus callosum

(2012) M. O. Bohlen et al.   GENES BRAIN AND BEHAVIOR

Novel Mutations Including Deletions of the EntireOFD1Gene in 30 Families with Type 1 Orofaciodigital Syndrome: A Study of the Extensive Clinical Variability

(2012) Izak J. Bisschoff et al.   HUMAN MUTATION

Dishevelled stabilization by the ciliopathy protein Rpgrip1l is essential for planar cell polarity

(2012) Alexia Mahuzier et al.   JOURNAL OF CELL BIOLOGY

Primary cilia and forebrain development

(2012) Marc August Willaredt et al.   MECHANISMS OF DEVELOPMENT

The Ciliogenic Transcription Factor RFX3 Regulates Early Midline Distribution of Guidepost Neurons Required for Corpus Callosum Development

(2012) Carine Benadiba et al.   PLoS Genetics

Gli Proteins in Development and Disease

(2011) Chi-chung Hui et al.   Annual Review of Cell and Developmental Biology

Mapping the NPHP-JBTS-MKS Protein Network Reveals Ciliopathy Disease Genes and Pathways

(2011) Liyun Sang et al.   CELL

Primary cilia control telencephalic patterning and morphogenesis via Gli3 proteolytic processing

(2011) L. Besse et al.   DEVELOPMENT

Basolateral rather than apical primary cilia on neuroepithelial cells committed to delamination

(2011) M. Wilsch-Brauninger et al.   DEVELOPMENT

RFX2 is broadly required for ciliogenesis during vertebrate development

(2011) Mei-I Chung et al.   DEVELOPMENTAL BIOLOGY

Cilia and Hedgehog: When and how was their marriage solemnized?

(2011) Sudipto Roy   DIFFERENTIATION

Mutations in KIF7 link Joubert syndrome with Sonic Hedgehog signaling and microtubule dynamics

(2011) Claudia Dafinger et al.   JOURNAL OF CLINICAL INVESTIGATION

Transcriptional control of genes involved in ciliogenesis: a first step in making cilia

(2010) Joëlle Thomas et al.   BIOLOGY OF THE CELL

Ofd1 is required in limb bud patterning and endochondral bone development

(2010) Sabrina Bimonte et al.   DEVELOPMENTAL BIOLOGY

Appropriate Bmp7 levels are required for the differentiation of midline guidepost cells involved in corpus callosum formation

(2010) Cristina Sánchez-Camacho et al.   Developmental Neurobiology

The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins

(2010) E. W. Humke et al.   GENES & DEVELOPMENT

Molecular regulation of the developing commissural plate

(2010) Randal X. Moldrich et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Kinetics of Hedgehog-Dependent Full-Length Gli3 Accumulation in Primary Cilia and Subsequent Degradation

(2010) X. Wen et al.   MOLECULAR AND CELLULAR BIOLOGY

The primary cilium: a signalling centre during vertebrate development

(2010) Sarah C. Goetz et al.   NATURE REVIEWS GENETICS

Functional modules, mutational load and human genetic disease

(2010) Norann A. Zaghloul et al.   TRENDS IN GENETICS

Development, specification, and diversity of callosal projection neurons

(2010) Ryann M. Fame et al.   TRENDS IN NEUROSCIENCES

Ttc21b is required to restrict sonic hedgehog activity in the developing mouse forebrain

(2009) R.W. Stottmann et al.   DEVELOPMENTAL BIOLOGY

CC2D2Amutations in Meckel and Joubert syndromes indicate a genotype-phenotype correlation

(2009) Soumaya Mougou-Zerelli et al.   HUMAN MUTATION

Hydrolethalus Syndrome

(2009) Anders Paetau et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

A common allele in RPGRIP1L is a modifier of retinal degeneration in ciliopathies

(2009) Hemant Khanna et al.   NATURE GENETICS

Multiple non-cell-autonomous defects underlie neocortical callosal dysgenesis in Nfib-deficient mice

(2009) Michael Piper et al.   Neural Development

Understanding the Mechanisms of Callosal Development Through the Use of Transgenic Mouse Models

(2009) Amber-Lee S. Donahoo et al.   Seminars in Pediatric Neurology

Establishing and Interpreting Graded Sonic Hedgehog Signaling during Vertebrate Neural Tube Patterning: The Role of Negative Feedback

(2009) V. Ribes et al.   Cold Spring Harbor Perspectives in Biology

Transient Neuronal Populations Are Required to Guide Callosal Axons: A Role for Semaphorin 3C

(2009) Mathieu Niquille et al.   PLOS BIOLOGY

CC2D2A Is Mutated in Joubert Syndrome and Interacts with the Ciliopathy-Associated Basal Body Protein CEP290

(2008) Nicholas T. Gorden et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Primary cilia are required for cerebellar development and Shh-dependent expansion of progenitor pool

(2008) N. Spassky et al.   DEVELOPMENTAL BIOLOGY

Intraflagellar transport protein 172 is essential for primary cilia formation and plays a vital role in patterning the mammalian brain

(2008) Marat Gorivodsky et al.   DEVELOPMENTAL BIOLOGY

Nuclear factor I gene expression in the developing forebrain

(2008) Céline Plachez et al.   JOURNAL OF COMPARATIVE NEUROLOGY

A Crucial Role for Primary Cilia in Cortical Morphogenesis

(2008) M. A. Willaredt et al.   JOURNAL OF NEUROSCIENCE

The genetics of early telencephalon patterning: some assembly required

(2008) Jean M. Hébert et al.   NATURE REVIEWS NEUROSCIENCE

Satb2 Is a Postmitotic Determinant for Upper-Layer Neuron Specification in the Neocortex

(2008) Olga Britanova et al.   NEURON

Satb2 Regulates Callosal Projection Neuron Identity in the Developing Cerebral Cortex

(2008) Elizabeth A. Alcamo et al.   NEURON