Homozygous mutation of PLCZ1 leads to defective human oocyte activation and infertility that is not rescued by the WW-binding protein PAWP

Sperm Postacrosomal WW Domain-Binding Protein Is Not Required for Mouse Egg Activation1

(2015) Yuhkoh Satouh et al.   BIOLOGY OF REPRODUCTION

Teratozoospermia: spotlight on the main genetic actors in the human

(2015) C. Coutton et al.   HUMAN REPRODUCTION UPDATE

Essential Role of the EF-hand Domain in Targeting Sperm Phospholipase Cζ to Membrane Phosphatidylinositol 4,5-Bisphosphate (PIP2)

(2015) Michail Nomikos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional disparity between human PAWP and PLCζ in the generation of Ca2+oscillations for oocyte activation

(2015) Michail Nomikos et al.   MOLECULAR HUMAN REPRODUCTION

Signaling through C2 domains: More than one lipid target

(2014) Senena Corbalan-Garcia et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Sperm-derived WW domain-binding protein, PAWP, elicits calcium oscillations and oocyte activation in humans and mice

(2014) Mahmoud Aarabi et al.   FASEB JOURNAL

Sperm content of postacrosomal WW binding protein is related to fertilization outcomes in patients undergoing assisted reproductive technology

(2014) Mahmoud Aarabi et al.   FERTILITY AND STERILITY

Protein phospholipase C Zeta1 expression in patients with failed ICSI but with normal sperm parameters

(2014) Hoi Chang Lee et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Dpy19l2-deficient globozoospermic sperm display altered genome packaging and DNA damage that compromises the initiation of embryo development

(2014) Sandra Yassine et al.   MOLECULAR HUMAN REPRODUCTION

Sperm-specific post-acrosomal WW-domain binding protein (PAWP) does not cause Ca2+ release in mouse oocytes

(2014) M. Nomikos et al.   MOLECULAR HUMAN REPRODUCTION

Subcellular localization of phospholipase Cζ in human sperm and its absence in DPY19L2-deficient sperm are consistent with its role in oocyte activation

(2014) Jessica Escoffier et al.   MOLECULAR HUMAN REPRODUCTION

A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium

(2014)   NATURE BIOTECHNOLOGY

Sperm PLCζ: From structure to Ca2+oscillations, egg activation and therapeutic potential

(2013) Michail Nomikos et al.   FEBS LETTERS

Phosphoinositide-specific Phospholipase C β 1b (PI-PLCβ1b) Interactome: Affinity Purification-Mass Spectrometry Analysis of PI-PLCβ1b with Nuclear Protein

(2013) Manuela Piazzi et al.   MOLECULAR & CELLULAR PROTEOMICS

Comprehensive analysis of sperm DNA fragmentation by five different assays: TUNEL assay, SCSA, SCD test and alkaline and neutral Comet assay

(2013) J. Ribas-Maynou et al.   Andrology

The Testicular and Epididymal Expression Profile of PLCζ in Mouse and Human Does Not Support Its Role as a Sperm-Borne Oocyte Activating Factor

(2012) Mahmoud Aarabi et al.   PLoS One

A maternally inherited autosomal point mutation in human phospholipase C zeta (PLC ) leads to male infertility

(2011) J. Kashir et al.   HUMAN REPRODUCTION

PLCζ causes Ca2+ oscillations in mouse eggs by targeting intracellular and not plasma membrane PI(4,5)P2

(2011) Yuansong Yu et al.   MOLECULAR BIOLOGY OF THE CELL

The evolution of gene expression levels in mammalian organs

(2011) David Brawand et al.   NATURE

TUNEL as a Test for Sperm DNA Damage in the Evaluation of Male Infertility

(2010) Rakesh K. Sharma et al.   UROLOGY

Reduced amounts and abnormal forms of phospholipase C zeta (PLC ) in spermatozoa from infertile men

(2009) E. Heytens et al.   HUMAN REPRODUCTION

Enzymatic assembly of DNA molecules up to several hundred kilobases

(2009) Daniel G Gibson et al.   NATURE METHODS

Complete globozoospermia associated with PLCζ deficiency treated with calcium ionophore and ICSI results in pregnancy

(2009) S.L. Taylor et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Human sperm devoid of PLC, zeta 1 fail to induce Ca2+ release and are unable to initiate the first step of embryo development

(2008) Sook-Young Yoon et al.   JOURNAL OF CLINICAL INVESTIGATION