The Warsaw breakage syndrome-related protein DDX11 is required for ribosomal RNA synthesis and embryonic development

Recent studies implicate the nucleolus as the major site of nuclear translation

(2014) Tina McLeod et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The cohesin acetyltransferase Eco1 coordinates rDNA replication and transcription

(2014) S. Lu et al.   EMBO REPORTS

Connecting the nucleolus to the cell cycle and human disease

(2014) Robert Y. L. Tsai et al.   FASEB JOURNAL

Combinatorial action of transcription factors orchestrates cell cycle-dependent expression of the ribosomal protein genes and ribosome biogenesis

(2014) Nagisa Nosrati et al.   FEBS Journal

Insight into the Roles of Helicase Motif Ia by Characterizing Fanconi Anemia Group J Protein (FANCJ) Patient Mutations

(2014) Manhong Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human diseases of the SSU processome

(2013) Samuel B. Sondalle et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Roles of ChlR1 DNA helicase in replication recovery from DNA damage

(2013) Niyant Shah et al.   EXPERIMENTAL CELL RESEARCH

Angiogenin Stimulates Ribosomal RNA Transcription by Epigenetic Activation of the Ribosomal DNA Promoter

(2013) Jinghao Sheng et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Expression of Epitope-Tagged SYN3 Cohesin Proteins Can Disrupt Meiosis in Arabidopsis

(2013) Li Yuan et al.   Journal of Genetics and Genomics

Histone modifications for human epigenome analysis

(2013) Hiroshi Kimura   JOURNAL OF HUMAN GENETICS

Cohesion promotes nucleolar structure and function

(2013) Bethany Harris et al.   MOLECULAR BIOLOGY OF THE CELL

Chl1 DNA Helicase Regulates Scc2 Deposition Specifically during DNA-Replication in Saccharomyces cerevisiae

(2013) Soumya Rudra et al.   PLoS One

Dysregulation of RNA polymerase I transcription during disease

(2012) K.M. Hannan et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Ribosome Biogenesis and Control of Cell Proliferation: p53 Is Not Alone

(2012) G. Donati et al.   CANCER RESEARCH

The ENU-induced cetus mutation reveals an essential role of the DNA helicase DDX11 for mesoderm development during early mouse embryogenesis

(2012) Christina D. Cota et al.   DEVELOPMENTAL DYNAMICS

Identification and Biochemical Characterization of a Novel Mutation inDDX11Causing Warsaw Breakage Syndrome

(2012) José-Mario Capo-Chichi et al.   HUMAN MUTATION

PHF6 Regulates Cell Cycle Progression by Suppressing Ribosomal RNA Synthesis

(2012) Jiadong Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DNA helicase and helicase-nuclease enzymes with a conserved iron-sulfur cluster

(2012) Y. Wu et al.   NUCLEIC ACIDS RESEARCH

A Role for the CAL1-Partner Modulo in Centromere Integrity and Accurate Chromosome Segregation in Drosophila

(2012) Chin-Chi Chen et al.   PLoS One

Dysregulation of upstream binding factor-1 acetylation at K352 is linked to impaired ribosomal DNA transcription in Huntington's disease

(2011) J Lee et al.   CELL DEATH AND DIFFERENTIATION

Biochemical Characterization of Warsaw Breakage Syndrome Helicase

(2011) Yuliang Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of DHX33 as a Mediator of rRNA Synthesis and Cell Growth

(2011) Y. Zhang et al.   MOLECULAR AND CELLULAR BIOLOGY

A role for the arginine methylation of Rad9 in checkpoint control and cellular sensitivity to DNA damage

(2011) Wei He et al.   NUCLEIC ACIDS RESEARCH

Epigenetic Silencing of Nucleolar rRNA Genes in Alzheimer's Disease

(2011) Maciej Pietrzak et al.   PLoS One

Warsaw Breakage Syndrome, a Cohesinopathy Associated with Mutations in the XPD Helicase Family Member DDX11/ChlR1

(2010) Petra van der Lelij et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Human DHX9 Helicase Unwinds Triple-Helical DNA Structures

(2010) Aklank Jain et al.   BIOCHEMISTRY

Ribosomopathies: human disorders of ribosome dysfunction

(2010) A. Narla et al.   BLOOD

PHF8 is a histone H3K9me2 demethylase regulating rRNA synthesis

(2010) Ziqi Zhu et al.   CELL RESEARCH

The role of UBF in regulating the structure and dynamics of transcriptionally active rDNA chromatin

(2010) Elaine Sanij et al.   Epigenetics

Mitotic Expression of Spo13 Alters M-Phase Progression and Nucleolar Localization of Cdc14 in Budding Yeast

(2010) E. Varela et al.   GENETICS

CHD7 functions in the nucleolus as a positive regulator of ribosomal RNA biogenesis

(2010) Gabriel E. Zentner et al.   HUMAN MOLECULAR GENETICS

When ribosomes go bad: diseases of ribosome biogenesis

(2010) Emily F. Freed et al.   Molecular BioSystems

PHF8 activates transcription of rRNA genes through H3K4me3 binding and H3K9me1/2 demethylation

(2010) Weijun Feng et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

1A6/DRIM, a Novel t-UTP, Activates RNA Polymerase I Transcription and Promotes Cell Proliferation

(2010) Qunhui Peng et al.   PLoS One

DEAD-box proteins as RNA helicases and chaperones

(2010) Inga Jarmoskaite et al.   Wiley Interdisciplinary Reviews-RNA

Intergenic transcripts originating from a subclass of ribosomal DNA repeats silence ribosomal RNA genes in trans

(2009) Raffaella Santoro et al.   EMBO REPORTS

PHF8, a gene associated with cleft lip/palate and mental retardation, encodes for an Nε-dimethyl lysine demethylase

(2009) Christoph Loenarz et al.   HUMAN MOLECULAR GENETICS

Mutations in C2orf37, Encoding a Nucleolar Protein, Cause Hypogonadism, Alopecia, Diabetes Mellitus, Mental Retardation, and Extrapyramidal Syndrome

(2008) Anas M. Alazami et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The Epigenetics of rRNA Genes: From Molecular to Chromosome Biology

(2008) Brian McStay et al.   Annual Review of Cell and Developmental Biology

Cell cycle dependent role of HDAC1 for proliferation control through modulating ribosomal DNA transcription

(2008) Joachim Meraner et al.   CELL BIOLOGY INTERNATIONAL

Nucleophosmin is required for chromosome congression, proper mitotic spindle formation, and kinetochore-microtubule attachment in HeLa cells

(2008) Mohammed Abdullahel Amin et al.   FEBS LETTERS

CANu1, a novel nucleolar protein, accumulated on centromere in response to DNA damage

(2008) Choong-Ryoul Sihn et al.   GENES TO CELLS

Studies with the Human Cohesin Establishment Factor, ChlR1

(2008) Andrea Farina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rad9 plays an important role in DNA mismatch repair through physical interaction with MLH1

(2008) W. He et al.   NUCLEIC ACIDS RESEARCH