Direct transfection of clonal organoids in Matrigel microbeads: a promising approach toward organoid-based genetic screens

Development of flexible nanocarriers for siRNA delivery into tumor tissue

(2017) Hyunkyung Jung et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

3D extracellular matrix interactions modulate tumour cell growth, invasion and angiogenesis in engineered tumour microenvironments

(2016) Anna V. Taubenberger et al.   Acta Biomaterialia

PTEN is required to maintain luminal epithelial homeostasis and integrity in the adult mammary gland

(2016) Amy N. Shore et al.   DEVELOPMENTAL BIOLOGY

Culture and establishment of self-renewing human and mouse adult liver and pancreas 3D organoids and their genetic manipulation

(2016) Laura Broutier et al.   Nature Protocols

Repression of p63 and induction of EMT by mutant Ras in mammary epithelial cells

(2016) Kathryn E. Yoh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A 3D Toolbox to Enhance Physiological Relevance of Human Tissue Models

(2016) Nathalie Picollet-D’hahan et al.   TRENDS IN BIOTECHNOLOGY

Influence of Matrices on 3D-Cultured Prostate Cancer Cells' Drug Response and Expression of Drug-Action Associated Proteins

(2016) Rasheena Edmondson et al.   PLoS One

Intracellular ROS mediates gas plasma-facilitated cellular transfection in 2D and 3D cultures

(2016) Dehui Xu et al.   Scientific Reports

Controlled 3D culture in Matrigel microbeads to analyze clonal acinar development

(2015) Monika E. Dolega et al.   BIOMATERIALS

A transfection method of PS-asODNs targeting ANGPTL4 in multicellular structures of hepatocarcinoma cell line

(2015) Q Kong et al.   CANCER GENE THERAPY

A kinome-targeted RNAi-based screen links FGF signaling to H2AX phosphorylation in response to radiation

(2015) Sami Benzina et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The need for complex 3D culture models to unravel novel pathways and identify accurate biomarkers in breast cancer

(2014) Britta Weigelt et al.   ADVANCED DRUG DELIVERY REVIEWS

Three-Dimensional Cell Culture Systems and Their Applications in Drug Discovery and Cell-Based Biosensors

(2014) Rasheena Edmondson et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Photochemical internalization-mediated nonviral gene transfection: polyamine core-shell nanoparticles as gene carrier

(2014) Genesis Zamora et al.   JOURNAL OF BIOMEDICAL OPTICS

Quantification of Dynamic Morphological Drug Responses in 3D Organotypic Cell Cultures by Automated Image Analysis

(2014) Ville Härmä et al.   PLoS One

Adenovirus-Mediated Efficient Gene Transfer into Cultured Three-Dimensional Organoids

(2014) Ning Wang et al.   PLoS One

Three-dimensional culture model to distinguish normal from malignant human bronchial epithelial cells

(2013) Delphine Fessart et al.   EUROPEAN RESPIRATORY JOURNAL

In vitro expansion and genetic modification of gastrointestinal stem cells in spheroid culture

(2013) Hiroyuki Miyoshi et al.   Nature Protocols

Generation of BAC Transgenic Epithelial Organoids

(2013) Gerald Schwank et al.   PLoS One

The histone methyltransferase MMSET/WHSC1 activates TWIST1 to promote an epithelial–mesenchymal transition and invasive properties of prostate cancer

(2012) T Ezponda et al.   ONCOGENE

Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer

(2012) P. Tucci et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-Throughput Transfection of Interfering RNA into a 3D Cell-Culture Chip

(2012) Haiyuan Zhang et al.   Small

Directing human embryonic stem cell differentiation by non-viral delivery of siRNA in 3D culture

(2011) Janet Zoldan et al.   BIOMATERIALS

A novel MCF-10A line allowing conditional oncogene expression in 3D culture

(2011) Ricarda Herr et al.   Cell Communication and Signaling

Controlled gene expression in primary Lgr5 organoid cultures

(2011) Bon-Kyoung Koo et al.   NATURE METHODS

Mammalian cell transfection: the present and the future

(2010) Tae Kyung Kim et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

A Comprehensive Panel of Three-Dimensional Models for Studies of Prostate Cancer Growth, Invasion and Drug Responses

(2010) Ville Härmä et al.   PLoS One

A 3D in vitro spheroid model as a way to study the mechanisms of electroporation

(2009) L. Wasungu et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS