Article
Forestry
Hao Wang, Dongyan Zhang, Juan Luis Fernandez-Lorenzo, Hailong Shen, Ling Yang
Summary: Programmed cell death occurs in browning explants of Fraxinus mandshurica during somatic embryogenesis, possibly due to the signaling roles of hydrogen peroxide and nitric oxide. Plant growth regulators and high sucrose concentrations promote this process.
JOURNAL OF FORESTRY RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Bin Tong, Yusun Shi, Aaron Ntambiyukuri, Xia Li, Jie Zhan, Aiqin Wang, Dong Xiao, Longfei He
Summary: This study investigated the regulatory mechanisms of programmed cell death (PCD) induced by aluminum (Al) stress in peanut. Through transcriptomics, sRNAs, and degradome analysis, a comprehensive resource of miRNAs and their target genes associated with PCD under Al stress was generated. GO and KEGG analysis revealed the involvement of metabolic pathways in response to Al stress. A regulatory network was constructed to provide new insights into plant stress response.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Plant Sciences
Shuzhen Luo, Chunliu Pan, Songying Liu, Guoting Liao, Ailing Li, Yalun Wang, Aiqin Wang, Dong Xiao, Long-Fei He, Jie Zhan
Summary: Aluminum toxicity in acidic soil is a common problem that leads to decreased crop yields. Programmed cell death (PCD) is an important mechanism in the plant response to aluminum toxicity. The plant cell wall of crop roots, particularly hemicellulose 1 (HC1), is the primary target of aluminum. The activity of xyloglucan endotransglucosylase (XET), specifically regulated by the transcription of AhXTH32, plays a crucial role in this process.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Junjun Huang, Ying Wang, Wenwen Liu, Xiaoyu Li, Rongzhi Han, Weihong Liang, Huahua Wang
Summary: The study reveals that the alternative pathway (AP) in soybean root tips can alleviate aluminum (Al) toxicity, while inhibition of AP can exacerbate Al-induced programmed cell death (PCD). Nitric oxide (NO) plays a negative role in Al-induced PCD, and the alleviating effect of NO on Al-induced PCD can be blocked by AP inhibition.
Article
Plant Sciences
Ruifen Ren, Hao Zhou, Lingling Zhang, Xueru Jiang, Yan Liu
Summary: This study investigated the effects of nitric oxide (NO) on programmed cell death (PCD) in Paeonia lactiflora 'Fen Yu Nu' pollen after cryopreservation, revealing that increased levels of NO correlated with higher apoptosis rates and decreased viability. The findings suggest that NO-induced PCD plays a significant role in the viability decline of pollen after cryopreservation.
PLANT CELL REPORTS
(2021)
Review
Plant Sciences
Adil Hussain, Farooq Shah, Farman Ali, Byung-Wook Yun
Summary: Senescence is the final stage of plant growth and development, involving significant changes at the transcriptional, post-translational, and metabolomic levels. Plant hormones and nitric oxide play crucial roles in aging and death processes.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Chemistry, Physical
Mengyu Sun, Yanjuan Sang, Qingqing Deng, Zhengwei Liu, Jinsong Ren, Xiaogang Qu
Summary: A nanozyme-based NO generator, cerium oxide (CeO2)-AT, has been developed to selectively produce nitric oxide (NO) in cancer cells for tumor treatment. The generator can disrupt the mitochondrial respiratory chain of tumor cells and induce cell apoptosis by catalyzing the production of NO in the mitochondria of cancer cells. Furthermore, the generator can improve the performance of NO gas therapy by catalyzing H2O2 to produce O-2. This study provides a new approach for safe and specific cancer therapy using highly selective NO-based treatment.
Article
Biochemistry & Molecular Biology
Thawatchai Khuanjing, Chayodom Maneechote, Benjamin Ongnok, Nanthip Prathumsap, Apiwan Arinno, Titikorn Chunchai, Busarin Arunsak, Siriporn C. Chattipakorn, Nipon Chattipakorn
Summary: This study found that donepezil protects against trastuzumab-induced cardiotoxicity by reducing mitochondrial dysfunction, oxidative stress, inflammation, and cardiomyocyte death, leading to improved left ventricular function through activation of muscarinic acetylcholine receptors. This provides a new intervention strategy for treating trastuzumab-induced cardiotoxicity.
MOLECULAR MEDICINE
(2023)
Article
Genetics & Heredity
Dong Xiao, Xia Li, Yun-Yi Zhou, Li Wei, Chanthaphoone Keovongkod, Huyi He, Jie Zhan, Ai-Qin Wang, Long-Fei He
Summary: The study identified key pathways and genes associated with aluminum stress in peanuts, showing that rapid transcriptomic response helps activate effective aluminum tolerance mechanisms, MAPK signal transduction plays important roles in early response to aluminum stress in peanuts, and there is a link between ethylene signaling transduction and aluminum resistance-related genes in peanuts.
Article
Plant Sciences
Karen C. Chamusco, May N. Milazzo, Kanchan S. Bhan, Terry L. Kamps, Prestina Smith, Modupeoluwa Durojaiye, Cristina D. Moreira, Maria Gallo, Christine D. Chase
Summary: Research found that collapse of CMS-S pollen is a programmed cell death event with morphological features similar to apoptosis regulated by mitochondria in animals. Typically, mitochondrial morphology and activity in CMS-S pollen differ significantly from normal pollen, possibly leading to decreased protection against mitochondrial generation of reactive oxygen species.
Article
Plant Sciences
Johanna Schwarze, James C. Carolan, Gavin S. Stewart, Paul F. McCabe, Joanna Kacprzyk
Summary: This study used Arabidopsis thaliana cell suspension culture to investigate the regulation of programmed cell death (PCD) induced by heat stress. The results revealed the changes in protein abundance and localization in both mitochondria and cytosol during the early stages of PCD.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Medicine, Research & Experimental
Chanon Piamsiri, Chayodom Maneechote, Kewarin Jinawong, Busarin Arunsak, Titikorn Chunchai, Wichwara Nawara, Siriporn C. Chattipakorn, Nipon Chattipakorn
Summary: Myocardial infarction (MI) is a leading cause of death worldwide, and oxidative stress, inflammation, and mitochondrial dysfunction are recognized as possible mechanisms in the development of MI. Different types of programmed cell death (PCDs), including apoptosis, necroptosis, ferroptosis, and pyroptosis, have been associated with different phases of ischemic injury following MI. However, it is still unknown which types of PCDs play the most dominant role in post-MI.
JOURNAL OF TRANSLATIONAL MEDICINE
(2023)
Article
Horticulture
Fan Guo, Airu Han, Haiyan Gao, Jingyi Liang, Ke Zhao, Shifeng Cao, Hongfei Wang, Yingying Wei, Xingfeng Shao, Feng Xu
Summary: Mannose treatment effectively inhibited chlorophyll degradation and programmed cell death in broccoli florets stored at 20 degrees Celsius, delaying senescence in broccoli florets.
SCIENTIA HORTICULTURAE
(2022)
Review
Agriculture, Multidisciplinary
Lijuan Liu, Lin Huang, Chengliang Sun, Luxuan Wang, Chongwei Jin, Xianyong Lin
Summary: Nitric oxide (NO) and hydrogen peroxide (H2O2) play critical roles as regulators in plants, interacting synergistically or antagonistically in various biological processes. Their interplay involves processes like hypersensitive response, stomatal movement, and plant responses to adverse conditions.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Article
Engineering, Biomedical
Haihui Wang, Yongfei Liu, Xiaohui Zhu, Chengyun Chen, Zhangcheng Fu, Min Wang, Danying Lin, Zhaowei Chen, Chunhua Lu, Huanghao Yang
Summary: The study developed a multi-stage cooperative nanodrug PtR/CPG for antitumor chemoimmunotherapy by direct self-assembly of Pt, l-Arg, and CPG, triggering immunogenic cell death, enhancing antigen presentation, and reversing immunosuppressive microenvironment, leading to increased sensitivity of tumors to immune checkpoint inhibitors.
ADVANCED HEALTHCARE MATERIALS
(2021)
Review
Plant Sciences
H. He, L. He, M. Gu
BIOLOGIA PLANTARUM
(2015)
Article
Engineering, Environmental
Huyi He, Wenjing Huang, Thet Lwin Oo, Minghua Gu, Long-Fei He
JOURNAL OF HAZARDOUS MATERIALS
(2017)
Review
Plant Sciences
Huyi He, Long-Fei He
PLANT CELL REPORTS
(2018)
Review
Environmental Sciences
Huyi He, Yingqiu Li, Long-Fei He
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2018)
Review
Biochemistry & Molecular Biology
Huyi He, Yingqiu Li, Long-Fei He
Article
Biochemistry & Molecular Biology
Yinqiu Li, Huyi He, Long-Fei He
MOLECULAR BIOLOGY REPORTS
(2019)
Review
Plant Sciences
Huyi He, Carlos Garcia-Mata, Long-Fei He
PLANT GROWTH REGULATION
(2019)
Review
Plant Sciences
H. He, Y. Li, L. -F. He
SOUTH AFRICAN JOURNAL OF BOTANY
(2019)
Article
Multidisciplinary Sciences
Huyi He, Thet Lwin Oo, Wenjing Huang, Long-Fei He, Minghua Gu
SCIENTIFIC REPORTS
(2019)
Review
Plant Sciences
Huyi He, Long-Fei He
PHYSIOLOGIA PLANTARUM
(2020)
Article
Genetics & Heredity
Dong Xiao, Xia Li, Yun-Yi Zhou, Li Wei, Chanthaphoone Keovongkod, Huyi He, Jie Zhan, Ai-Qin Wang, Long-Fei He
Summary: The study identified key pathways and genes associated with aluminum stress in peanuts, showing that rapid transcriptomic response helps activate effective aluminum tolerance mechanisms, MAPK signal transduction plays important roles in early response to aluminum stress in peanuts, and there is a link between ethylene signaling transduction and aluminum resistance-related genes in peanuts.
Review
Plant Sciences
Jinni Li, Huyi He, Yingqiu Li, Aiqin Wang, Long-Fei He
Summary: This paper summarizes the research advances on the classification, structural features, and biological function of long non-coding RNA (lncRNA). It also explains the key role of lncRNA in plant stress tolerance.
ACTA PHYSIOLOGIAE PLANTARUM
(2022)
Article
Agronomy
Yingqiu Li, Huyi He, Long-Fei He
Summary: This study identified and analyzed 54 potato PME genes through bioinformatics methods, revealing their structural, physicochemical properties, conserved domains and evolutionary relationships. The genes were divided into two groups and five subfamilies, providing valuable information for further research on the function of potato PME genes.
Review
Biochemistry & Molecular Biology
Huyi He, Long-Fei He
PLANT SIGNALING & BEHAVIOR
(2019)
Article
Biochemistry & Molecular Biology
Julia Claudiane da Veiga, Neidiquele Maria Silveira, Amedea Barozzi Seabra, Ilana Urbano Bron
Summary: This review investigates the strategy of using nitric oxide (NO) donors to extend postharvest shelf-life and improve fruit quality, discusses the interactions between NO and ethylene or reactive oxygen species, and highlights the potential of nanotechnology in NO applications.
NITRIC OXIDE-BIOLOGY AND CHEMISTRY
(2024)
