Article
Rehabilitation
Jie Li, Ying Ying, Fan Su, Liwen Chen, Jingrui Yang, Jie Jia, Xiaofeng Jia, Wendong Xu
Summary: This study proposed the Hua-Shan rehabilitation program for patients undergoing contralateral seventh cervical nerve transfer, and found that it had significant advantages in improving postoperative functional recovery compared to traditional rehabilitation methods.
DISABILITY AND REHABILITATION
(2022)
Review
Clinical Neurology
Wenmiao Luo, Zhengcun Yan, Yu Guo, Ji Xu, Heng-Zhu Zhang
Summary: This study evaluated the efficacy and safety of contralateral C7 nerve transfer for central spastic paralysis of the upper extremity caused by cerebral nerve injury. The findings showed that patients who underwent CC7 transfer had improved motor function, range of motion, and reduced spasticity in the paralyzed upper extremity.
FRONTIERS IN NEUROLOGY
(2023)
Article
Medicine, General & Internal
Juntao Feng, Tie Li, Minzhi Lv, Sangsoo Kim, Joon-Ho Shin, Naiqing Zhao, Qingzhong Chen, Yanpei Gong, Yucheng Sun, Zaixing Zhao, Ning Zhu, Jihua Cao, Wen Fang, Bin Chen, Song Zheng, Zhu Xu, Xin Jin, Yundong Shen, Yanqun Qiu, Huawei Yin, Su Jiang, Jie Li, Ying Ying, Liwen Chen, Ying Liu, Jie Jia, Chuntao Zuo, Jianguang Xu, Yudong Gu, Wendong Xu
Summary: This study retrospectively investigated the efficacy and safety of contralateral seventh cervical nerve (CC7) cross transfer in restoring arm function of patients with spastic arm paralysis. The results showed that the surgery provided effective, safe, and stable functional improvements in the long-term follow-up, supporting the expansion of indications for the surgery.
Article
Anesthesiology
Fan Su, Ye Xu, Xiaoqian Wang, Yiqun Zhou, Wendong Xu, Yaojin Zhang, Ying Liu
Summary: The Huashan nursing program, based on preoperative evaluations, educational sessions, postoperative monitoring, and targeted nursing, effectively improved the quality of care and outcomes for patients undergoing CC7 surgery. The program successfully alleviated postoperative adverse events and maximized the benefits of CC7 surgery.
PERIOPERATIVE MEDICINE
(2022)
Article
Surgery
Hua-Li Zhao, Yun Gao, Ai-Ping Yu, Yi-Min Wei, Yun-Dong Shen, Su Jiang, Yan-Qun Qiu, Jing Yu, Zong-Hui Liang
Summary: This study explores the optimization of the prespinal route using MRI for contralateral cervical 7 nerve transfer. The middle route was found to be the optimal choice, with a low rate of nerve transplantation and no serious complications.
FRONTIERS IN SURGERY
(2022)
Article
Clinical Neurology
Hyun-Joo Lee, Hyun-Sil Cha, Myong-Hun Hahm, Huijoong Lee, Sang Soo Kim, Yongmin Chang
Summary: Contralateral C7 nerve transfer surgery may improve spasticity and motor function in spastic hemiplegia patients by altering the function of the brain white matter tract, as shown in this study involving a 62-year-old female patient.
CLINICAL NEUROLOGY AND NEUROSURGERY
(2021)
Article
Clinical Neurology
Wen-Dong Xu
Summary: The contralateral C7 transfer has been used for the treatment of brachial plexus root avulsion since 1986. The Xu's CC7 procedure offers a safer and more efficient technique for contralateral C7 to C7 cross nerve transfer, reducing surgical trauma, surgery time, postoperative recovery time, and nerve regeneration time. The detailed description in this article provides meaningful information for surgeons interested in the procedure.
OPERATIVE NEUROSURGERY
(2021)
Article
Medicine, General & Internal
Jingyu Guan, Jun Lin, Xueqing Guan, Qiang Jin, Wenchuan Zhang
Summary: C7 nerve transfer and selective posterior rhizotomy can individually improve upper limb motor function and spasticity, respectively. Combining contralateral C7 nerve transfer and SPR for patients with upper limb dysfunction can possibly lead to improved surgical outcomes. More studies are needed to validate this novel approach.
Article
Clinical Neurology
Jayme A. Bertelli, Mayur Sureshlal Goklani, Neehar Patel, Elisa Cristiana Winkelmann Duarte
Summary: Through the axillary anterior arm approach, the anatomy of the radial nerve and its branches can be clearly dissected and individualized, as well as all heads of the triceps muscle. In most dissections, a single branch to the long head and dual innervations for the lateral and medial heads were observed.
JOURNAL OF NEUROSURGERY
(2022)
Article
Neurosciences
Ting Yang, Xueping Li, Peng Xia, Xiaoju Wang, Jianqiang Lu, Lin Wang
Summary: This study evaluated the effect of rTMS combined with rPMS on stroke patients with arm paralysis after CSCNTS. The results showed that this combined treatment significantly reduced muscle tone and increased grip and pinch strength.
INTERNATIONAL JOURNAL OF NEUROSCIENCE
(2023)
Article
Behavioral Sciences
Zeyu Cai, Gaowei Lei, Jie Li, Yundong Shen, Yudong Gu, Juntao Feng, Wendong Xu
Summary: Contralateral C7 nerve transfer can aid in motor and sensory recovery in TBPI, but synchronous sensation often persists postoperatively. Central plasticity may play a role in sensory recovery, with sensory functioning of the injured hand dominated by its ipsilateral SI and overlapping with the intact hand's representative area.
BRAIN AND BEHAVIOR
(2021)
Article
Multidisciplinary Sciences
Camille Finck, Tersia Gambron, Lionel Benchimol, Severine Camby, Dominique Morsomme
Summary: Neuroborreliosis, a rare manifestation of Lyme disease, can cause damage to cranial and/or peripheral nerves. This case report describes a patient with two episodes of vocal fold paralysis as a possible manifestation of Lyme neuroborreliosis. Serological evidence from both serum and cerebrospinal fluid support this diagnosis. Prompt treatment with doxycycline resulted in rapid recovery.
Review
Medicine, General & Internal
Ali M. Alawieh, Nicholas Au Yong, Nicholas M. Boulis
Summary: Ischemic stroke remains a major cause of disability; while treatment for subacute and chronic strokes is challenging, surgical intervention using contralateral C7 nerve transfer has shown added benefit in improving motor performance and reducing spasticity. However, level 1 evidence for efficacy in ischemic stroke research is still limited.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Clinical Neurology
Sara Ratican, Michael Song, Yanqun Qiu, Jiang Su, Jennifer Hong, Wendong Xu
Summary: This study examined the anatomical variations of donor C7 nerve roots in patients undergoing CC7 surgery, revealing that right-sided donor C7 roots have significantly longer branches compared to the left side. Patient factors such as age, sex, or laterality of brain injury did not affect intraoperative anatomy.
WORLD NEUROSURGERY
(2021)
Article
Clinical Neurology
Jayme Augusto Bertelli, Sushil Nehete, Elisa Cristiana Winkelmann Duarte, Neehar Patel, Marcos Flavio Ghizoni
Summary: The distal motor branch of the pronator teres can be used for reinnervation of the extensor carpi radialis brevis in patients with radial nerve paralysis, with successful outcomes observed in patients followed for at least 24 months postoperatively.
JOURNAL OF NEUROSURGERY
(2021)
Article
Neuroimaging
Zhen-Zhen Ma, Ye-Chen Lu, Jia-Jia Wu, Xu-Yun Hua, Si-Si Li, Wei Ding, Jian-Guang Xu
Summary: The study revealed the impact of postparalysis facial synkinesis on interactions among brain networks, indicating that specific coupling patterns can mitigate motor deficits, providing new therapeutic avenues for specific reorganization within couplings in the rehabilitation of facial function.
BRAIN IMAGING AND BEHAVIOR
(2022)
Article
Endocrinology & Metabolism
Yu-Lin Li, Jia-Jia Wu, Jie Ma, Si-Si Li, Xin Xue, Dong Wei, Chun-Lei Shan, Xu-Yun Hua, Mou-Xiong Zheng, Jian-Guang Xu
Summary: The aim of this study was to investigate the interactive effect between aging and type 2 diabetes mellitus (T2DM) on brain glucose metabolism, individual metabolic connectivity, and network properties. The results showed an interaction effect between aging and T2DM on glucose metabolism, metabolic connectivity, and regional metabolic network properties. Elderly patients with T2DM had decreased glucose metabolism, increased metabolic connectivity, and regional metabolic network properties in cognition-related brain regions.
Article
Dermatology
Haonan Guan, Di Zhang, Xian Ma, Yechen Lu, Jiaoyun Dong, Yiwen Niu, Yingkai Liu, Shuliang Lu, Jiping Xu, Jiajun Tang
Summary: The study found that fully ablative CO2 laser debridement has several advantages over routine sharp surgical debridement in treating chronic wounds. It is superior at ameliorating wound status, reducing wound area, and significantly reducing the time-to-heal for chronic wounds, without causing any adverse events.
LASERS IN SURGERY AND MEDICINE
(2022)
Editorial Material
Cell Biology
Jie Ma, Xu-Yun Hua, Mou-Xiong Zheng, Jia-Jia Wu, Bei-Bei Huo, Xiang-Xin Xing, Sheng-Yi Feng, Bo Li, Jian-Guang Xu
Summary: Patients with hip disorder show plasticity changes in sensorimotor- and pain-related regions in the brain.
NEURAL REGENERATION RESEARCH
(2022)
Article
Cell Biology
Si-Si Li, Xu-Yun Hua, Mou-Xiong Zheng, Jia-Jia Wu, Zhen-Zhen Ma, Xiang-Xin Xing, Jie Ma, Chun-Lei Shan, Jian-Guang Xu
Summary: Electroacupuncture (EA) can improve neurological function after stroke by regulating the activity of the brain-derived neurotrophic factor/tyrosine kinase B signal pathway.
NEURAL REGENERATION RESEARCH
(2022)
Article
Neurosciences
Rong Xu, Guang-Yue Zhu, Jun Zhu, Yong Wang, Xiang-Xin Xing, Lin-Yu Chen, Jie Li, Fu-Qiang Shen, Jian-Bing Chen, Xu-Yun Hua, Dong-Sheng Xu
Summary: The study is a 4-month double-blind randomized sham-controlled clinical trial aimed at evaluating the effects of cortico-peripheral Hebbian-type stimulation on neural circuit reconstruction for upper-extremity hemiplegia after stroke. 90 post-stroke individuals with mild to moderate upper limb paralysis will be recruited and assessed using measures such as the Wolf Motor Function Test to observe the outcomes of the HTS intervention.
FRONTIERS IN NEURAL CIRCUITS
(2022)
Article
Medicine, General & Internal
Yu-Jie Duan, Xu-Yun Hua, Mou-Xiong Zheng, Jia-Jia Wu, Xiang-Xin Xing, Yu-Lin Li, Jian-Guang Xu
Summary: This study aims to investigate the effects of corticocortical paired associative stimulation (ccPAS) on the synaptic plasticity in treating paralysis caused by stroke. The study is designed as a 14-week double-blind randomized sham-controlled clinical trial, consisting of a 2-week intervention period and a 12-week follow-up period.
Article
Geriatrics & Gerontology
Xiang-Xin Xing, Zhen-Zhen Ma, Jia-Jia Wu, Jie Ma, Yu-Jie Duan, Xu-Yun Hua, Mou-Xiong Zheng, Jian-Guang Xu
Summary: This study found that there is weakened connectivity in the bilateral S1 of patients with CTS, and the information output from the dominant hemisphere to the contralateral hemisphere is reduced. These results provide reliable evidence for understanding the neuropathophysiological mechanisms of decreased functional integration in the brains of patients with CTS.
FRONTIERS IN AGING NEUROSCIENCE
(2022)
Article
Geriatrics & Gerontology
Xin Xue, Jia-Jia Wu, Bei-Bei Huo, Xiang-Xin Xing, Jie Ma, Yu-Lin Li, Dong Wei, Yu-Jie Duan, Chun-Lei Shan, Mou-Xiong Zheng, Xu-Yun Hua, Jian-Guang Xu
Summary: This study explored the effects of aging on the topological properties and rich-club organization of individual brain metabolic networks in rats. The findings revealed that aged rats had significantly decreased clustering coefficient and local efficiency in the whole-brain metabolic network compared to young rats. Furthermore, certain brain areas exhibited increased degree and nodal efficiency in aged rats. The study also demonstrated that rich-club connections were susceptible to aging, as the overall strength of these connections decreased while the overall strength of feeder and local connections increased in aged rats.
FRONTIERS IN AGING NEUROSCIENCE
(2022)
Article
Neurosciences
Lu Li, Jie Ma, Xuyun Hua, Yan Zhou, Yage Qiu, Zhen Zhu, Yanling Zheng, Qian Xie, Zonghui Liang, Jianguang Xu
Summary: This study found changes in the brain functional networks in patients with CD, and these changes were related to CD clinical indices. These findings provide more insights into the pathophysiological mechanisms of brain plasticity in CD.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Neurosciences
Jie Ma, Jia-Jia Wu, Xiang-Xin Xing, Bei-Bei Huo, Xin Gao, Zhen-Zhen Ma, Si-Si Li, Mou-Xiong Zheng, Xu-Yun Hua, Jian-Guang Xu
Summary: This study investigated the brain metabolic patterns in patients with colorectal cancer and chronic enteritis using positron emission tomography. The findings suggest that patients with colorectal cancer exhibit a characteristic cerebral metabolic pattern involving visceral sensation and affective and cognitive psychological processes. The study also identified potential neuroimaging markers for non-pharmaceutical therapies.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Neurosciences
Zhen-Zhen Ma, Jia-Jia Wu, Xu-Yun Hua, Mou-Xiong Zheng, Xiang-Xin Xing, Jie Ma, Si-Si Li, Chun-Lei Shan, Jian-Guang Xu
Summary: This study explored the relationship between motor imagery ability and specific modulation of movement-related regions in stroke patients. The results showed that enhanced activations in the contralateral precentral gyrus and postcentral gyrus during motor execution tasks contributed to reversing motor dysfunction in stroke patients. In contrast, inhibition of the contralateral anterior cingulate cortex during motor imagery tasks improved impaired imagery ability.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Neurosciences
Chen-hao Zhang, Han-qi Wang, Yong Lu, Wei Wang, Hao Ma, Ye-chen Lu
Summary: Facial synkinesis patients show weakened structural connections but enhanced functional transmission from rich-club nodes. Two potential biomarkers, rich-club edge density and structural-functional coupling strength, may serve as indicators of disease outcome.
Article
Anesthesiology
Ao-Lin Hou, Jia-Jia Wu, Xiang-Xin Xing, Bei-Bei Huo, Jun Shen, Xu-Yun Hua, Mou-Xiong Zheng, Jian-Guang Xu
Summary: This study utilized multivariate pattern analysis of PET scans in rats' brains to successfully differentiate neuropathic pain from healthy condition at the individual level, and identified specific brain regions that could potentially serve as neuroimaging biomarkers for neuropathic pain following brachial plexus avulsion injury (BPAI).