Article
Clinical Neurology
Fraser Henderson Jr, Brett E. Youngerman, Sumit N. Niogi, Tyler Alexander, Abtin Tabaee, Ashutosh Kacker, Vijay K. Anand, Theodore H. Schwartz
Summary: The aim of this study was to determine if the distinction between planum sphenoidale (PS) and tuberculum sellae (TS) meningiomas is clinically meaningful and impacts the results of the endoscopic endonasal approach (EEA). The study found that PS meningiomas were larger and more likely to invade the optic canals. The surgical outcomes for both PS and TS meningiomas were similar.
JOURNAL OF NEUROSURGERY
(2023)
Article
Clinical Neurology
Brett E. Youngerman, Matei A. Banu, Mina M. Gerges, Eseosa Odigie, Abtin Tabaee, Ashutosh Kacker, Vijay K. Anand, Theodore H. Schwartz
Summary: In this study, the authors identified preoperative risk factors associated with incomplete resection of suprasellar meningiomas using the endoscopic endonasal approach. A newly proposed resectability score was found to successfully predict the likelihood of gross total resection (GTR). Long-term recurrence rates varied significantly based on the extent of resection, with GTR significantly reducing recurrence compared to near-total resection (NTR) and subtotal resection (STR).
JOURNAL OF NEUROSURGERY
(2021)
Article
Otorhinolaryngology
Terence S. Fu, Christopher M. K. L. Yao, Hedyeh Ziai, Eric Monteiro, Joao Paulo Almeida, Gelareh Zadeh, Fred Gentili, John R. de Almeida
Summary: Cost-utility analysis comparing EEA and transcranial approaches for OGM showed that EEA may be a cost-effective alternative under specific conditions. This study provides insights into the relative cost-effectiveness of different surgical approaches for olfactory groove meningiomas.
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
(2021)
Article
Clinical Neurology
Pierre-Olivier Champagne, Georgios A. Zenonos, Eric W. Wang, Carl H. Snyderman, Paul A. Gardner
Summary: This study retrospectively analyzed different groups of patients treated with endoscopic endonasal surgery for olfactory groove meningiomas, and found that the rate of postoperative cerebrospinal fluid leak and the time to resolution of brain edema significantly decreased over time. The results of this study support the use of endoscopic endonasal surgery as a safe and effective approach for treating olfactory groove meningiomas.
OPERATIVE NEUROSURGERY
(2023)
Article
Neurosciences
Prasheelkumar P. Gupta, Salman T. Shaikh, Chandrashekhar E. Deopujari, Nishit J. Shah
Summary: Endoscopic trans-nasal surgery has advanced significantly in treating suprasellar meningiomas, providing superior tumor excision results and visual outcomes, while greatly reducing the occurrence of CSF leaks.
Article
Clinical Neurology
Christopher B. Cutler, J. Curran Henson, Jeremiah Alt, Michael Karsy
Summary: This article presents a minimally invasive, endonasal approach for the resection of giant olfactory groove meningiomas (OGMs) in a 68-year-old female patient.
ACTA NEUROCHIRURGICA
(2022)
Article
Clinical Neurology
Ronak Ved, Matthew Mo, Caroline Hayhurst
Summary: Controversy exists regarding optimal approaches for tuberculum sella meningioma (TSM) and planum meningioma (PM). This study reviewed olfactory outcomes after supraorbital craniotomy for TSM or PM, finding that olfactory changes can improve within the first year after surgery and should be considered when selecting a surgical approach and counseling patients.
JOURNAL OF NEUROLOGICAL SURGERY PART B-SKULL BASE
(2022)
Article
Multidisciplinary Sciences
Peng Yu, Tutu Xu, Xinyu Wu, Zhitong Liu, Yong Wang, Yibao Wang
Summary: The expanded endoscopic endonasal approach (EEEA) shows advantages in treating tuberculum sellae meningioma (TSM) with good therapeutic effects, but also carries risks of complications such as cerebrospinal fluid leakage and meningitis.
SCIENTIFIC REPORTS
(2021)
Article
Clinical Neurology
Adomas Bunevicius, Jungeun Ahn, Sarah Fribance, Selcuk Peker, Batu Hergunsel, Darrah Sheehan, Kimball Sheehan, Ahmed M. Nabeel, Wael A. Reda, Sameh R. Tawadros, Khaled Abdelkarim, Amr M. N. El-Shehaby, Reem M. Emad, Tomas Chytka, Roman Liscak, Roberto Martinez Alvarez, Nuria Martinez Moreno, Anne-Marie Langlois, David Mathieu, Cheng-Chia Lee, Huai-Che Yang, Manjul Tripathi, Ronald E. Warnick, Herwin Speckter, Camilo Albert, Piero Picozzi, Andrea Franzini, Luca Attuati, Ben A. Strickland, Gabriel Zada, Eric L. Chang, Caleb E. Feliciano Valls, Carlos H. Carbini, Samir Patel, Jason Sheehan
Summary: The study shows that SRS treatment provides durable local control for patients with olfactory groove meningiomas, with an acceptable safety profile, and allows preservation or improvement of olfactory function in the majority of patients.
Review
Oncology
Ciro Mastantuoni, Luigi Maria Cavallo, Felice Esposito, Elena d'Avella, Oreste de Divitiis, Teresa Somma, Andrea Bocchino, Gianluca Lorenzo Fabozzi, Paolo Cappabianca, Domenico Solari
Summary: Skull base meningiomas have always been a challenge for neurosurgeons due to their location and surrounding neurovascular structures. This comprehensive review examines the indications and techniques for managing skull base meningiomas, highlighting the ambivalent and complementary role of the low and high routes.
Article
Clinical Neurology
Regin Jay Mallari, Jai Deep Thakur, John H. Rhee, Amalia Eisenberg, Howard Krauss, Chester Griffiths, Walavan Sivakumar, Garni Barkhoudarian, Daniel F. Kelly
Summary: The study demonstrates that both endonasal and supraorbital approaches are safe and effective for tuberculum sellae meningioma removal. Endonasal approach may be preferred for most cases due to easier access to optic canals and better tumor removal.
OPERATIVE NEUROSURGERY
(2021)
Article
Clinical Neurology
Regin Jay Mallari, Jai Deep Thakur, John H. Rhee, Amalia Eisenberg, Howard Krauss, Chester Griffiths, Walavan Sivakumar, Garni Barkhoudarian, Daniel F. Kelly
Summary: This study demonstrated that both endonasal and supraorbital approaches are safe and effective for removing tuberculum sellae meningiomas (TSM). Larger tumors and lateral extension favor the supraorbital route, while tumors with greater extension below the planum and invasion of the optic canal favor the endonasal route.
OPERATIVE NEUROSURGERY
(2021)
Article
Clinical Neurology
Michael A. Mooney, Walid Ibn Essayed, Ossama Al-Mefty
Summary: Tuberculum sellae meningiomas can lead to progressive visual loss and require surgical removal. Optic canal extension is a consistent feature of these tumors, and complete resection with skull base reconstruction is crucial for successful treatment.
OPERATIVE NEUROSURGERY
(2021)
Article
Surgery
Orhan Beger, Ilhan Bahsi
Summary: The study identified different types of chiasmatic ridge which can affect the risk of residual tumor formation during tumor removal surgery, particularly Type 3 CR should be carefully considered by neurosurgeons.
JOURNAL OF CRANIOFACIAL SURGERY
(2021)
Article
Clinical Neurology
Kuntal Kanti Das, Kavindra Singh, Anant Mehrotra, Awadhesh Kumar Jaiswal
Summary: This study describes a contralateral supraorbital eyebrow approach (c-SEA) as a minimally invasive option for tuberculum sellae meningioma (TSM) resection. The surgery was performed using a 2x2 cm craniotomy. The patient improved after surgery and postoperative imaging confirmed complete tumor resection.
ACTA NEUROCHIRURGICA
(2023)
Review
Endocrinology & Metabolism
Egidio Candela, Emanuele La Corte, Stefano Zucchini, Mariella Lefosse, Francesco Toni, Mino Zucchelli
Summary: This case report presents a patient with growth hormone deficiency (GHD) due to ectopic posterior pituitary and Chiari malformation type I (CM-1). The patient experienced headache and worsening of CM-1 after receiving rhGH therapy, but showed improvement after decompression surgery. It is important to closely monitor CM-1 patients receiving GH therapy for any neurological symptoms.
HORMONE RESEARCH IN PAEDIATRICS
(2023)
Article
Clinical Neurology
Christian S. Kassicieh, Alexander J. Kassicieh, Kavelin Rumalla, Evan N. Courville, Kyril L. Cole, Syed Faraz Kazim, Christian A. Bowers, Meic H. Schmidt
Summary: A predictive model for hospital-acquired infection (HAI) occurrence following spinal tumor surgery was developed. Severe frailty, nonelective surgery, and hypoalbuminemia were identified as independent predictors of HAI occurrence. A logistic regression model utilizing frailty score, along with preoperative characteristics, showed moderate predictive ability for HAI occurrence.
CLINICAL NEUROLOGY AND NEUROSURGERY
(2023)
Article
Clinical Neurology
Michael M. Covell, Kavelin Rumalla, Alexander J. Kassicieh, Aaron C. Segura, Syed Faraz Kazim, Meic H. Schmidt, Christian A. Bowers
Summary: This study aimed to evaluate the accuracy of preoperative frailty, measured by the Risk Analysis Index (RAI), in predicting postoperative morbidity among adult spine deformity surgery patients. The results showed that RAI had a strong predictive accuracy for postoperative morbidity in adult spine deformity surgery. This is important for improving patient outcomes and treatment strategies.
Letter
Clinical Neurology
Dante N. Rangel, Kavelin Rumalla, Meic H. Schmidt, Christian A. Bowers
Article
Clinical Neurology
Joshua S. Catapano, Kavelin Rumalla, Stefan W. Koester, Ethan A. Winkler, Robert F. Rudy, Tyler S. Cole, Jacob F. Baranoski, Christopher S. Graffeo, Visish M. Srinivasan, Ruchira M. Jha, Ashutosh P. Jadhav, Andrew F. Ducruet, Felipe C. Albuquerque, Michael T. Lawton
Summary: This study investigated the incidence and risk factors for chronic depression after aneurysmal subarachnoid hemorrhage (aSAH). The study found that smoking, illicit drug use, alcohol use disorder, chronic obstructive pulmonary disease (COPD), and vasospasm requiring angioplasty were associated with higher rates of depression. The proposed predictive model may be a useful tool for early screening and evaluation of high-risk patients for depression.
WORLD NEUROSURGERY
(2023)
Article
Clinical Neurology
Kavelin Rumalla, Rachel Thommen, Syed Faraz Kazim, Aaron C. Segura, Alexander J. Kassicieh, Meic H. Schmidt, Christian A. Bowers
Summary: This study aims to evaluate the discriminative accuracy of preoperative Risk Analysis Index (RAI) frailty score for predicting mortality or transition to hospice within 30 days of brain tumor resection (BTR) in a large multicenter, international, prospective database. The relationship between RAI frailty scale and the primary end point was assessed using statistical tests and ROC curve analysis.
JOURNAL OF NEUROLOGICAL SURGERY PART B-SKULL BASE
(2023)
Article
Medicine, General & Internal
Jacopo Falco, Emanuele Rubiu, Morgan Broggi, Mariangela Farinotti, Ignazio G. Vetrano, Marco Schiariti, Elena Anghileri, Marica Eoli, Bianca Pollo, Marco Moscatelli, Francesco Restelli, Elio Mazzapicchi, Emanuele La Corte, Giulio Bonomo, Marco Gemma, Giovanni Broggi, Paolo Ferroli, Francesco Acerbi
Summary: Maximizing surgical resection using fluorescein-guided surgery has been shown to improve overall survival in patients with glioblastoma. In this retrospective analysis, we evaluated the role of fluorescein-guided surgery in tumor resection, survival, and complications. The study results demonstrated a high rate of complete resection without any adverse effects related to fluorescein. The survival and progression-free survival were significantly improved compared to previous studies.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Oncology
Paolo Ferroli, Francesco Restelli, Giacomo Bertolini, Emanuele Monti, Jacopo Falco, Giulio Bonomo, Irene Tramacere, Bianca Pollo, Chiara Calatozzolo, Monica Patane, Silvia Schiavolin, Morgan Broggi, Francesco Acerbi, Alessandra Erbetta, Silvia Esposito, Elio Mazzapicchi, Emanuele La Corte, Ignazio Gaspare Vetrano, Giovanni Broggi, Marco Schiariti
Summary: This retrospective study analyzed the associations between possible prognostic factors and survival rate. Surgical resection, tumor volume, histological grade, extent of resection, and 3-month postoperative performance status were identified as important prognostic factors. Surgery for thalamic gliomas improves overall survival, and patients with stable performance status after 3 months have better prognosis. Therefore, accurate evaluation of predictors of 3-month postoperative performance status is crucial in deciding between biopsy or surgical removal.
Letter
Clinical Neurology
Kavelin Rumalla, Syed Faraz Kazim, Priyanka Jain, Rohini G. McKee, Meic H. Schmidt, Christian A. Bowers
Article
Clinical Neurology
Kavelin Rumalla, Joshua S. Catapano, Varun Mahadevan, Samuel R. Sorkhi, Stefan W. Koester, Ethan A. Winkler, Christopher S. Graffeo, Visish M. Srinivasan, Ruchira M. Jha, Ashutosh P. Jadhav, Andrew F. Ducruet, Felipe C. Albuquerque, Michael T. Lawton
Summary: This study analyzed factors that may influence patient outcomes after aneurysmal sub-arachnoid hemorrhage (aSAH), including having a primary care physician, family/caregiver support, language barrier, primary payer status, and race. It found that patients with a PCP, caregiver support, and white race had better long-term outcomes after aSAH.
WORLD NEUROSURGERY
(2023)
Review
Medicine, General & Internal
Malte Ottenhausen, Elena Greco, Giacomo Bertolini, Andrea Gerosa, Salvatore Ippolito, Erik H. Middlebrooks, Graziano Serrao, Maria Grazia Bruzzone, Francesco Costa, Paolo Ferroli, Emanuele La Corte
Summary: The craniovertebral junction is a complex area between the skull and cervical spine. Pathologies in this area can lead to joint instability. There is no consensus on fixation techniques after craniovertebral oncological surgery. This review summarizes the anatomy, pathology, and available surgical approaches for joint instability in this area.
Article
Clinical Neurology
Alexander J. Kassicieh, Kavelin Rumalla, Aaron C. Segura, Syed Faraz Kazim, John Vellek, Meic H. Schmidt, Peter C. Shin, Christian A. Bowers
Summary: Objective: This study compares endoscopic spine surgery (ESS) and non-ESS approaches for single-level lumbar decompression, and proposes a frailty-driven predictive model for nonhome discharge (NHD) disposition. After propensity score matching, ESS is associated with reduced operative time, shorter hospital length of stay (LOS), and decreased NHD.
Article
Oncology
Michael M. Covell, Charles Bowers, Syed Faraz Kazim, Samantha Varela, Kavelin Rumalla, Meic H. Schmidt, Christian A. Bowers
Summary: By querying a large international surgical registry, we found that preoperative lab values have predictive accuracy for postoperative outcomes of metastatic brain tumor resection. Hypoalbuminemia, thrombocytopenia, and anemia were the strongest predictors of adverse postoperative outcomes.
Review
Clinical Neurology
Joanna M. Roy, Christian A. Bowers, Kavelin Rumalla, Michael M. Covell, Syed Faraz Kazim, Meic H. Schmidt
Summary: Preoperative frailty quantification is crucial in neuro-surgical decision making. Patients with metastatic spine tumors undergoing surgery are frail and experience unfavorable outcomes, leading to increased treatment costs. The lack of a universally accepted definition for frailty and variation in validation of frailty indexes result in imprecise predictions for neurosurgical outcomes. This review examines the role of reported frailty indexes in predicting postoperative outcomes and aims to assist clinical decision making as a frailty guide.
WORLD NEUROSURGERY
(2023)
Article
Clinical Neurology
Emanuele La Corte, Micol Babini, Giada Bortoluzzi, Mino Zucchelli
Summary: This study describes the key steps of an endoscopic trans-ventricular biopsy for brainstem diffuse midline gliomas, providing a valid technique for diagnosis and molecular markers for future targeted therapies.
ACTA NEUROCHIRURGICA
(2023)