Article
Neurosciences
N. Coquelet, X. De Tiege, L. Roshchupkina, P. Peigneux, S. Goldman, M. Woolrich, V Wens
Summary: Research has shown that there are significant differences in spatial and temporal aspects between microstates and power envelope HMM states. Microstates reflect sharp events of neural synchronization, whereas power envelope HMM states disclose network-level activity with 100-200 ms lifetimes.
Review
Cell Biology
Chloe C. Casagrande, Maggie P. Rempe, Seth D. Springer, Tony W. Wilson
Summary: With the aging population and the rise of cognitive decline and neurodegenerative disorders, understanding Alzheimer's disease (AD) has become crucial. Neuroimaging, including PET, fMRI, MEG, and EEG, has provided novel insights into AD pathology. This review focuses on task-based M/EEG studies since 2010, investigating cognitive domains most affected by AD and recommending adjustments for optimal use in this population.
AGEING RESEARCH REVIEWS
(2023)
Article
Behavioral Sciences
Frigyes Samuel Racz, Kinga Farkas, Orestis Stylianou, Zalan Kaposzta, Akos Czoch, Peter Mukli, Gabor Csukly, Andras Eke
Summary: This study analyzed EEG recordings of SZ patients and healthy controls, revealing spectral abnormalities in SZ related to frequency shifts, suggesting the significant role of scale-free neural activity in SZ.
BRAIN AND BEHAVIOR
(2021)
Article
Neurosciences
Pierpaolo Sorrentino, Emahnuel Troisi Lopez, Antonella Romano, Carmine Granata, Marie Constance Corsi, Giuseppe Sorrentino, Viktor Jirsa
Summary: This study demonstrates that the non-linear part of brain signals carries individual-specific information, playing a crucial role in differentiation. By using neuronal avalanches to characterize fast dynamics between individuals, and comparing with Pearson's correlation, the study shows that selecting the moments and places where neuronal avalanches spread can improve differentiation.
Article
Biophysics
Carolina Moncion, Lakshmini Balachandar, Satheesh Bojja Venkatakrishnan, John L. Volakis, Jorge Riera Diaz
Summary: This article introduces a wireless, implantable, and battery-free neurosensing system (WiNS) and evaluates its multichannel recording capabilities in vivo for the first time. The results show that WiNS can perform multichannel recordings with a maximum sampling rate of approximately 10 kHz, and the recorded neuronal activity is comparable to that recorded with a wired system. This suggests that WiNS can match the performance of more invasive recording systems.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Clinical Neurology
Patrick Greene, Adam Li, Jorge Gonzalez-Martinez, Sridevi V. Sarma
Summary: SEEG is used to monitor brain signals and identify epileptogenic regions. An automated method based on signal and depth is presented to classify contacts, achieving good classification performance.
FRONTIERS IN NEUROLOGY
(2021)
Article
Oncology
Diana Cristina Ghinda, Ben Lambert, Junfeng Lu, Ning Jiang, Eve Tsai, Adam Sachs, Jin-Song Wu, Georg Northoff
Summary: The study demonstrated distinct power law exponent features in the tumoral tissue for the first time, potentially providing a novel electrophysiological marker in the future. The significant features observed in the peritumoral tissue of gliomas indicate the area where both the onset of epileptiform activity and the tumor infiltration occur.
FRONTIERS IN ONCOLOGY
(2021)
Article
Neurosciences
Frederik D. Weber, Gernot G. Supp, Jens G. Klinzing, Matthias Moelle, Andreas K. Engel, Jan Born
Summary: The study found that there is a temporal relationship between spindles and gamma activity, but the phase of this coupling varies across different spindles. This suggests that spindles might help synchronize gamma activity occurring in larger cortical networks and link local memory processing between distributed networks.
Article
Astronomy & Astrophysics
Anton Chudaykin, Mikhail M. Ivanov, Marko Simonovic
Summary: This paper discusses the impact of theoretical uncertainties in large-scale structure data analysis and how to incorporate these uncertainties in power spectrum likelihoods. The inclusion of theoretical errors has several advantages over the standard practice of using k(max) sharp momentum cut, providing reliable constraints with unbiased error bars. In realistic settings, the theoretical error likelihood yields essentially the same parameter constraints as the standard analysis, effectively optimizing the choice of k(max).
Article
Neurosciences
Lauren R. Ott, Samantha H. Penhale, Brittany K. Taylor, Brandon J. Lew, Yu-Ping Wang, Vince D. Calhoun, Julia M. Stephen, Tony W. Wilson
Summary: The study found significant changes in spontaneous cortical activity during the transition from childhood to adolescence, with sex differences in power across different frequency bands. These sex differences were particularly pronounced in certain cortical areas.
Article
Neurosciences
Guiomar Niso, Laurens R. Krol, Etienne Combrisson, A. Sophie Dubarry, Madison A. Elliott, Clement Francois, Yseult Hejja-Brichard, Sophie K. Herbst, Karim Jerbi, Vanja Kovic, Katia Lehongre, Steven J. Luck, Manuel Mercier, John C. Mosher, Yuri G. Pavlov, Aina Puce, Antonio Schettino, Daniele Schon, Walter Sinnott-Armstrong, Bertille Somon, Andela Soskic, Suzy J. Styles, Roni Tibon, Martina G. Vilas, Marijn van Vliet, Maximilien Chaumon
Summary: Good Scientific Practice (GSP) refers to rules, recommendations, and guidelines that help scientists produce high-quality work and share it with the community. In the context of MEEG research, GSP includes technical standards and guidelines, as well as a consideration of personal, organizational, and societal factors.
Article
Clinical Neurology
Christian A. Mikutta, Robert T. Knight, Daniela Sammler, Thomas J. Mueller, Thomas Koenig
Summary: This study demonstrates the correlation between EEG microstates and the spectral activity of electocortical field potentials. It is the first study to show distinct activation/deactivation patterns of frequency-domain ECoG local field potentials associated with simultaneous EEG microstates.
Article
Psychology, Biological
J. Christopher Edgar, Rose E. Franzen, Marybeth McNamee, Heather L. Green, Guannan Shen, Marissa DiPiero, Song Liu, Megan Airey, Sophia Goldin, Lisa Blaskey, Emily S. Kuschner, Mina Kim, Kimberly Konka, Timothy P. L. Roberts, Yuhan Chen
Summary: In a relaxed and awake state with the eyes closed, neural oscillations at 8-12 Hz are dominant, particularly in the parietal-occipital regions. Resting-state alpha is associated with processing speed and how networks process information. Previous research suggests that obtaining resting-state alpha measures in a dark room with the eyes open is a viable alternative to the traditional eyes-closed exam. This study further explored this alternative and found good reliability for alpha frequency in both conditions, indicating the dark room exam as a viable method in populations typically excluded from electrophysiology studies.
Article
Neurosciences
Bryan M. Krause, Declan Campbell, Christopher K. Kovach, Rashmi N. Mueller, Hiroto Kawasaki, Kirill Nourski, Matthew Banks
Summary: Theories of consciousness suggest that brain mechanisms underlying transitions into and out of unconsciousness are conserved no matter the context or precipitating conditions. We compared signatures of these mechanisms using intracranial electroencephalography in neurosurgical patients during propofol anesthesia and overnight sleep and found strikingly similar reorganization of human cortical networks. This network reorganization constitutes a neural signature of states of reduced consciousness that is common to anesthesia and sleep.
Review
Genetics & Heredity
Pierre Desaunay, Berengere Guillery, Edgar Moussaoui, Francis Eustache, Dermot M. Bowler, Fabian Guenole
Summary: The atypical memory functioning in autism spectrum disorder (ASD) has significant impact on daily living, academic learning, and cognitive remediation. This systematic review of neuroimaging studies highlights functional brain asymmetries in ASD individuals during memory processing, involving greater activity in the left hemisphere, posterior brain regions including the hippocampus, and the ventral streams rather than the dorsal ones. These functional alterations may explain the specific memory processes in ASD, such as verbal dominance, impaired active maintenance in working memory, and preserved relational memory despite poor context processing in episodic memory.
Article
Neurosciences
Bhim M. Adhikari, Juergen Dukart, Joerg F. Hipp, Anna Forsyth, Rebecca McMillan, Suresh D. Muthukumaraswamy, Meghann C. Ryan, L. Elliot Hong, Simon B. Eickhoff, Neda Jahandshad, Paul M. Thompson, Laura M. Rowland, Peter Kochunov
HUMAN BRAIN MAPPING
(2020)
Article
Anesthesiology
Andria Pelentritou, Levin Kuhlmann, John Cormack, Will Woods, Suresh Muthukumaraswamy, David Liley
Article
Neurosciences
Lionel Barnett, Suresh D. Muthukumaraswamy, Robin L. Carhart-Harris, Anil K. Seth
Article
Clinical Neurology
Rebecca McMillan, Rachael Sumner, Anna Forsyth, Doug Campbell, Gemma Malpas, Elizabeth Maxwell, Carolyn Deng, John Hay, Rhys Ponton, Frederick Sundram, Suresh Muthukumaraswamy
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2020)
Article
Clinical Neurology
Yaqub Jonmohamadi, Suresh Muthukumaraswamy, Joseph Chen, Jonathan Roberts, Ross Crawford, Ajay Pandey
Article
Clinical Neurology
Bethany Routley, Alexander Shaw, Suresh D. Muthukumaraswamy, Krish D. Singh, Khalid Hamandi
Article
Clinical Neurology
Rachael L. Sumner, Rebecca McMillan, Meg J. Spriggs, Doug Campbell, Gemma Malpas, Elizabeth Maxwell, Carolyn Deng, John Hay, Rhys Ponton, Frederick Sundram, Suresh D. Muthukumaraswamy
EUROPEAN NEUROPSYCHOPHARMACOLOGY
(2020)
Review
Behavioral Sciences
Rachael L. Sumner, Meg J. Spriggs, Suresh D. Muthukumaraswamy, Ian J. Kirk
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2020)
Review
Neurosciences
Rebecca McMillan, Suresh D. Muthukumaraswamy
REVIEWS IN THE NEUROSCIENCES
(2020)
Article
Clinical Neurology
Rachael L. Sumner, Emme Chacko, Rebecca McMillan, Meg J. Spriggs, Christie Anderson, James Chen, Amelia French, SungHun Jung, Akshaya Rajan, Gemma Malpas, John Hay, Rhys Ponton, Suresh D. Muthukumaraswamy, Frederick Sundram
Summary: The study explores the psychedelic experiences and sustained impact of ketamine in major depressive disorder. Results suggest that greater antidepressant response is associated with dimensions of altered states of consciousness like spirituality and insight. Participants experienced perceptual changes, loss of control, emotional and mood changes, as well as a psychedelic afterglow with changed perspectives on life, people, and problems.
JOURNAL OF PSYCHOPHARMACOLOGY
(2021)
Article
Medicine, Research & Experimental
Robin J. Murphy, Rachael L. Sumner, William Evans, David Menkes, Ingo Lambrecht, Rhys Ponton, Frederick Sundram, Nicholas Hoeh, Sanya Ram, Lisa Reynolds, Suresh Muthukumaraswamy
Summary: This study aims to rigorously examine the benefits of microdosing psychedelics in cognitive and emotional domains, as well as explore the potential therapeutic implications for conditions like depression and addiction. By pairing a comparable dosing protocol with objective measures, the study aims to provide more concrete evidence to support the claims made in the grey literature.
Article
Clinical Neurology
Alexander D. Shaw, Hannah L. Chandler, Khalid Hamandi, Suresh D. Muthukumaraswamy, Alexander Hammers, Krish D. Singh
Summary: This study investigated the effects of increasing local concentrations of GABA by blocking the reuptake with a GABA transporter 1 (GAT1) blocker, tiagabine. The results showed changes in whole brain activity and functional connectivity across different frequency bands following tiagabine administration, with alterations in frontal and posterior regions. The spatial distribution of these changes overlapped with the distribution of GABA(A) receptors, indicating a link between GABA availability, receptor distribution, and low-frequency network oscillations.
EUROPEAN NEUROPSYCHOPHARMACOLOGY
(2021)
Review
Pharmacology & Pharmacy
Suresh D. Muthukumaraswamy, Anna Forsyth, Thomas Lumley
Summary: This study reviewed previous literature on expectancy effects and blinding in psychedelic RCTs and found that these trials might be influenced by de-blinding and expectancy. Current psychedelic RCTs generally do not report pre-trial expectancy or the success rate of blinding procedures. The authors suggest caution in interpreting effect size estimates from existing psychedelic RCTs due to potential confounds related to de-blinding and expectancy.
EXPERT REVIEW OF CLINICAL PHARMACOLOGY
(2021)
Article
Neurosciences
Alexander D. Shaw, Suresh D. Muthukumaraswamy, Neeraj Saxena, Rachael L. Sumner, Natalie E. Adams, Rosalyn J. Moran, Krish D. Singh
Article
Neurosciences
Rachael L. Sumner, Rebecca McMillan, Meg J. Spriggs, Doug Campbell, Gemma Malpas, Elizabeth Maxwell, Carolyn Deng, John Hay, Rhys Ponton, Ian J. Kirk, Frederick Sundram, Suresh D. Muthukumaraswamy
BIOLOGICAL PSYCHIATRY-COGNITIVE NEUROSCIENCE AND NEUROIMAGING
(2020)
Article
Neurosciences
Jose Sanchez-Bornot, Roberto C. Sotero, J. A. Scott Kelso, Ozguer Simsek, Damien Coyle
Summary: This study proposes a multi-penalized state-space model for analyzing unobserved dynamics, using a data-driven regularization method. Novel algorithms are developed to solve the model, and a cross-validation method is introduced to evaluate regularization parameters. The effectiveness of this method is validated through simulations and real data analysis, enabling a more accurate exploration of cognitive brain functions.