标题
Breast cancer brain metastasis: molecular mechanisms and directions for treatment
作者
关键词
-
出版物
NEURO-ONCOLOGY
Volume -, Issue -, Pages -
出版商
Oxford University Press (OUP)
发表日期
2018-03-16
DOI
10.1093/neuonc/noy044
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Clinical trial design for systemic agents in patients with brain metastases from solid tumours: a guideline by the Response Assessment in Neuro-Oncology Brain Metastases working group
- (2018) D Ross Camidge et al. LANCET ONCOLOGY
- Modernizing Clinical Trial Eligibility Criteria: Recommendations of the American Society of Clinical Oncology–Friends of Cancer Research Brain Metastases Working Group
- (2017) Nancy U. Lin et al. JOURNAL OF CLINICAL ONCOLOGY
- OlympiAD: Phase III trial of olaparib monotherapy versus chemotherapy for patients (pts) with HER2-negative metastatic breast cancer (mBC) and a germline BRCA mutation (gBRCAm).
- (2017) Mark E. Robson et al. JOURNAL OF CLINICAL ONCOLOGY
- Diagnosis and treatment of brain metastases from solid tumors: guidelines from the European Association of Neuro-Oncology (EANO)
- (2017) Riccardo Soffietti et al. NEURO-ONCOLOGY
- Brain Metastases in Newly Diagnosed Breast Cancer
- (2017) Allison M. Martin et al. JAMA Oncology
- Efficacy and safety of trastuzumab emtansine (T-DM1) in patients with HER2-positive breast cancer with brain metastases
- (2016) William Jacot et al. BREAST CANCER RESEARCH AND TREATMENT
- Translational Breast Cancer Research Consortium (TBCRC) 022: A Phase II Trial of Neratinib for Patients With Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer and Brain Metastases
- (2016) Rachel A. Freedman et al. JOURNAL OF CLINICAL ONCOLOGY
- Exosomal Annexin II Promotes Angiogenesis and Breast Cancer Metastasis
- (2016) Sayantan Maji et al. MOLECULAR CANCER RESEARCH
- Carcinoma–astrocyte gap junctions promote brain metastasis by cGAMP transfer
- (2016) Qing Chen et al. NATURE
- Upregulation of MEK5 by Stat3 promotes breast cancer cell invasion and metastasis
- (2016) Fang Liu et al. ONCOLOGY REPORTS
- Mechanosensitive caveolin-1 activation-induced PI3K/Akt/mTOR signaling pathway promotes breast cancer motility, invadopodia formation and metastasis in vivo
- (2016) Hong Yang et al. Oncotarget
- Neratinib Plus Paclitaxel vs Trastuzumab Plus Paclitaxel in Previously Untreated Metastatic ERBB2-Positive Breast Cancer
- (2016) Ahmad Awada et al. JAMA Oncology
- Bevacizumab Preconditioning Followed by Etoposide and Cisplatin Is Highly Effective in Treating Brain Metastases of Breast Cancer Progressing from Whole-Brain Radiotherapy
- (2015) Y.-S. Lu et al. CLINICAL CANCER RESEARCH
- Roles of the Cyclooxygenase 2 Matrix Metalloproteinase 1 Pathway in Brain Metastasis of Breast Cancer
- (2015) Kerui Wu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- CEREBEL (EGF111438): A Phase III, Randomized, Open-Label Study of Lapatinib Plus Capecitabine Versus Trastuzumab Plus Capecitabine in Patients With Human Epidermal Growth Factor Receptor 2–Positive Metastatic Breast Cancer
- (2015) Xavier Pivot et al. JOURNAL OF CLINICAL ONCOLOGY
- Predicting early brain metastases based on clinicopathological factors and gene expression analysis in advanced HER2-positive breast cancer patients
- (2015) Renata Duchnowska et al. JOURNAL OF NEURO-ONCOLOGY
- Response assessment criteria for brain metastases: proposal from the RANO group
- (2015) Nancy U Lin et al. LANCET ONCOLOGY
- III-Tubulin Regulates Breast Cancer Metastases to the Brain
- (2015) D. Kanojia et al. MOLECULAR CANCER THERAPEUTICS
- Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets
- (2015) P. K. Brastianos et al. Cancer Discovery
- Stat3 orchestrates interaction between endothelial and tumor cells and inhibition of Stat3 suppresses brain metastasis of breast cancer cells
- (2015) Hsueh-Te Lee et al. Oncotarget
- Mutational profiling of brain metastasis from breast cancer: matched pair analysis of targeted sequencing between brain metastasis and primary breast cancer
- (2015) Ji Yun Lee et al. Oncotarget
- 64Cu-DOTA-trastuzumab PET imaging and HER2 specificity of brain metastases in HER2-positive breast cancer patients
- (2015) Hiroaki Kurihara et al. EJNMMI Research
- Neratinib overcomes trastuzumab resistance in HER2 amplified breast cancer
- (2015) Alexandra Canonici et al. Oncotarget
- Astrocytes Upregulate Survival Genes in Tumor Cells and Induce Protection from Chemotherapy
- (2015) Sun-Jin Kim et al. NEOPLASIA
- Trastuzumab emtansine (T-DM1) versus lapatinib plus capecitabine in patients with HER2-positive metastatic breast cancer and central nervous system metastases: a retrospective, exploratory analysis in EMILIA
- (2014) I. E. Krop et al. ANNALS OF ONCOLOGY
- TBCRC 018: phase II study of iniparib in combination with irinotecan to treat progressive triple negative breast cancer brain metastases
- (2014) Carey Anders et al. BREAST CANCER RESEARCH AND TREATMENT
- Serpins Promote Cancer Cell Survival and Vascular Co-Option in Brain Metastasis
- (2014) Manuel Valiente et al. CELL
- PSGL-1 and E/P-selectins are essential for T-cell rolling in inflamed CNS microvessels but dispensable for initiation of EAE
- (2014) Karthik Sathiyanadan et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Expression and correlation of matrix metalloproteinase-9 and heparanase in patients with breast cancer
- (2014) Dabei Tang et al. MEDICAL ONCOLOGY
- Analysis of tumour- and stroma-supplied proteolytic networks reveals a brain-metastasis-promoting role for cathepsin S
- (2014) Lisa Sevenich et al. NATURE CELL BIOLOGY
- Capecitabine and lapatinib uptake in surgically resected brain metastases from metastatic breast cancer patients: a prospective study
- (2014) Aki Morikawa et al. NEURO-ONCOLOGY
- Role of the endothelin axis in astrocyte- and endothelial cell-mediated chemoprotection of cancer cells
- (2014) Seung Wook Kim et al. NEURO-ONCOLOGY
- Safety Profile of Pertuzumab With Trastuzumab and Docetaxel in Patients From Asia With Human Epidermal Growth Factor Receptor 2-Positive Metastatic Breast Cancer: Results From the Phase III Trial CLEOPATRA
- (2014) Sandra M. Swain et al. ONCOLOGIST
- Frequent Genetic Alterations in EGFR- and HER2-Driven Pathways in Breast Cancer Brain Metastases
- (2013) Ina Hohensee et al. AMERICAN JOURNAL OF PATHOLOGY
- Personalizing the treatment of women with early breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2013
- (2013) A. Goldhirsch et al. ANNALS OF ONCOLOGY
- B-Crystallin: A Novel Regulator of Breast Cancer Metastasis to the Brain
- (2013) D. Malin et al. CLINICAL CANCER RESEARCH
- Reactive astrocytes promote the metastatic growth of breast cancer stem-like cells by activating Notch signalling in brain
- (2013) Fei Xing et al. EMBO Molecular Medicine
- Role of the Blood-Brain Barrier in the Formation of Brain Metastases
- (2013) Imola Wilhelm et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Angiopoietin-2 mediates blood-brain barrier impairment and colonization of triple-negative breast cancer cells in brain
- (2013) Hava Karsenty Avraham et al. JOURNAL OF PATHOLOGY
- Cell type-dependent pathogenic functions of overexpressed human cathepsin B in murine breast cancer progression
- (2013) F Bengsch et al. ONCOGENE
- Expression of tissue levels of matrix metalloproteinases and their inhibitors in breast cancer
- (2012) Ming Zhang et al. BREAST
- Lapatinib plus capecitabine in patients with previously untreated brain metastases from HER2-positive metastatic breast cancer (LANDSCAPE): a single-group phase 2 study
- (2012) Thomas Bachelot et al. LANCET ONCOLOGY
- Clinical relevance of cyclooxygenase-2 and matrix metalloproteinases (MMP-2 and MT1-MMP) in human breast cancer tissue
- (2012) Mohammad A. Mohammad et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Angiotensin II Facilitates Breast Cancer Cell Migration and Metastasis
- (2012) Sylvie Rodrigues-Ferreira et al. PLoS One
- Activating HER2 Mutations in HER2 Gene Amplification Negative Breast Cancer
- (2012) Ron Bose et al. Cancer Discovery
- Integrin β4 Signaling Promotes Mammary Tumor Cell Adhesion to Brain Microvascular Endothelium by Inducing ErbB2-Mediated Secretion of VEGF
- (2011) Jie Fan et al. ANNALS OF BIOMEDICAL ENGINEERING
- Caveolin-1 Upregulation Mediates Suppression of Primary Breast Tumor Growth and Brain Metastases by Stat3 Inhibition
- (2011) W.-T. Chiu et al. CANCER RESEARCH
- MicroRNA-1258 Suppresses Breast Cancer Brain Metastasis by Targeting Heparanase
- (2011) L. Zhang et al. CANCER RESEARCH
- Lapatinib Distribution in HER2 Overexpressing Experimental Brain Metastases of Breast Cancer
- (2011) Kunal S. Taskar et al. PHARMACEUTICAL RESEARCH
- Transmigration of Melanoma Cells through the Blood-Brain Barrier: Role of Endothelial Tight Junctions and Melanoma-Released Serine Proteases
- (2011) Csilla Fazakas et al. PLoS One
- Clinical outcome of patients with brain metastases from HER2-positive breast cancer treated with lapatinib and capecitabine
- (2010) G. Metro et al. ANNALS OF ONCOLOGY
- Treatment of HER2-positive metastatic breast cancer with lapatinib and capecitabine in the lapatinib expanded access programme, including efficacy in brain metastases – the UK experience
- (2010) S Sutherland et al. BRITISH JOURNAL OF CANCER
- CXCL12, CXCR4 and CXCR7 expression in brain metastases
- (2010) Andrea Salmaggi et al. CANCER BIOLOGY & THERAPY
- β-catenin-independent WNT signaling in basal-like breast cancer and brain metastasis
- (2010) F. Klemm et al. CARCINOGENESIS
- Interaction between lung cancer cells and astrocytes via specific inflammatory cytokines in the microenvironment of brain metastasis
- (2010) Toshihiro Seike et al. CLINICAL & EXPERIMENTAL METASTASIS
- Metastatic Behavior of Breast Cancer Subtypes
- (2010) Hagen Kennecke et al. JOURNAL OF CLINICAL ONCOLOGY
- Genome remodelling in a basal-like breast cancer metastasis and xenograft
- (2010) Li Ding et al. NATURE
- HER Family Receptor Abnormalities in Lung Cancer Brain Metastases and Corresponding Primary Tumors
- (2009) M. Sun et al. CLINICAL CANCER RESEARCH
- Multicenter Phase II Study of Lapatinib in Patients with Brain Metastases from HER2-Positive Breast Cancer
- (2009) N. U. Lin et al. CLINICAL CANCER RESEARCH
- Genes that mediate breast cancer metastasis to the brain
- (2009) Paula D. Bos et al. NATURE
- Real-time imaging reveals the single steps of brain metastasis formation
- (2009) Yvonne Kienast et al. NATURE MEDICINE
- The Vascular Basement Membrane as “Soil” in Brain Metastasis
- (2009) W. Shawn Carbonell et al. PLoS One
- Activation of tumor cell integrin v 3 controls angiogenesis and metastatic growth in the brain
- (2009) M. Lorger et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A phase III randomized comparison of lapatinib plus capecitabine versus capecitabine alone in women with advanced breast cancer that has progressed on trastuzumab: updated efficacy and biomarker analyses
- (2008) David Cameron et al. BREAST CANCER RESEARCH AND TREATMENT
- Identification of brain- and bone-specific breast cancer metastasis genes
- (2008) Andreas Klein et al. CANCER LETTERS
- Role of the CXCR4/CXCL12 signaling axis in breast cancer metastasis to the brain
- (2008) Cimona V. Hinton et al. CLINICAL & EXPERIMENTAL METASTASIS
- Astrocyte, the star avatar: redefined
- (2008) Pankaj Seth et al. JOURNAL OF BIOSCIENCES
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started