TRF1 participates in chromosome end protection by averting TRF2-dependent telomeric R loops

Functions of Replication Protein A as a Sensor of R Loops and a Regulator of RNaseH1

(2017) Hai Dang Nguyen et al.   MOLECULAR CELL

TRF2 binds branched DNA to safeguard telomere integrity

(2017) Isabelle Schmutz et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

TRF2 binds branched DNA to safeguard telomere integrity

(2017) Isabelle Schmutz et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Life and cancer without telomerase: ALT and other strategies for making sure ends (don’t) meet

(2016) Manasi S. Apte et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

TRF2-Mediated Control of Telomere DNA Topology as a Mechanism for Chromosome-End Protection

(2016) Delphine Benarroch-Popivker et al.   MOLECULAR CELL

R loops: new modulators of genome dynamics and function

(2015) José M. Santos-Pereira et al.   NATURE REVIEWS GENETICS

Complex interactions between the DNA-damage response and mammalian telomeres

(2015) Nausica Arnoult et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Replicating through telomeres: a means to an end

(2015) Paula Martínez et al.   TRENDS IN BIOCHEMICAL SCIENCES

Telomere functions grounding on TERRA firma

(2015) Claus M. Azzalin et al.   TRENDS IN CELL BIOLOGY

Elevated levels of TRF2 induce telomeric ultrafine anaphase bridges and rapid telomere deletions

(2015) Bernadette Nera et al.   Nature Communications

Complex interactions between the DNA-damage response and mammalian telomeres

(2015) Nausica Arnoult et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

ATM and ATR Signaling Regulate the Recruitment of Human Telomerase to Telomeres

(2015) Adrian S. Tong et al.   Cell Reports

TRF1 negotiates TTAGGG repeat-associated replication problems by recruiting the BLM helicase and the TPP1/POT1 repressor of ATR signaling

(2014) Michal Zimmermann et al.   GENES & DEVELOPMENT

RNaseH1 regulates TERRA-telomeric DNA hybrids and telomere maintenance in ALT tumour cells

(2014) Rajika Arora et al.   Nature Communications

Super-Resolution Fluorescence Imaging of Telomeres Reveals TRF2-Dependent T-loop Formation

(2013) Ylli Doksani et al.   CELL

Telomeric RNA-DNA hybrids affect telomere-length dynamics and senescence

(2013) Bettina Balk et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Telomerase-Dependent 3' G-Strand Overhang Maintenance Facilitates GTBP1-Mediated Telomere Protection from Misplaced Homologous Recombination

(2013) Y. W. Lee et al.   PLANT CELL

Removal of Shelterin Reveals the Telomere End-Protection Problem

(2012) A. Sfeir et al.   SCIENCE

Mammalian Telomeres Resemble Fragile Sites and Require TRF1 for Efficient Replication

(2009) Agnel Sfeir et al.   CELL

TRF2 promotes, remodels and protects telomeric Holliday junctions

(2009) Anaïs Poulet et al.   EMBO JOURNAL

Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice

(2009) P. Martinez et al.   GENES & DEVELOPMENT

TERRA RNA Binding to TRF2 Facilitates Heterochromatin Formation and ORC Recruitment at Telomeres

(2009) Zhong Deng et al.   MOLECULAR CELL

CpG-island promoters drive transcription of human telomeres

(2009) S. G. Nergadze et al.   RNA