Defective germline reprogramming rewires the spermatogonial transcriptome

Long terminal repeats power evolution of genes and gene expression programs in mammalian oocytes and zygotes

(2017) Vedran Franke et al.   GENOME RESEARCH

Rb family proteins enforce the homeostasis of quiescent hematopoietic stem cells by repressing Socs3 expression

(2017) Eunsun Kim et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A transit-amplifying population underpins the efficient regenerative capacity of the testis

(2017) Claudia Carrieri et al.   JOURNAL OF EXPERIMENTAL MEDICINE

mRNA 3′ uridylation and poly(A) tail length sculpt the mammalian maternal transcriptome

(2017) Marcos Morgan et al.   NATURE

Principles of early human development and germ cell program from conserved model systems

(2017) Toshihiro Kobayashi et al.   NATURE

A MILI-independent piRNA biogenesis pathway empowers partial germline reprogramming

(2017) Lina Vasiliauskaitė et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A MILI-independent piRNA biogenesis pathway empowers partial germline reprogramming

(2017) Lina Vasiliauskaitė et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Switching of dominant retrotransposon silencing strategies from posttranscriptional to transcriptional mechanisms during male germ-cell development in mice

(2017) Kota Inoue et al.   PLoS Genetics

The Germ Cell Fate of Cynomolgus Monkeys Is Specified in the Nascent Amnion

(2016) Kotaro Sasaki et al.   DEVELOPMENTAL CELL

FOXC1 maintains the hair follicle stem cell niche and governs stem cell quiescence to preserve long-term tissue-regenerating potential

(2016) Kenneth Lay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The DNA methyltransferase DNMT3C protects male germ cells from transposon activity

(2016) Joan Barau et al.   SCIENCE

Return to quiescence of mouse neural stem cells by degradation of a proactivation protein

(2016) Noelia Urbán et al.   SCIENCE

A Unique Gene Regulatory Network Resets the Human Germline Epigenome for Development

(2015) Walfred W.C. Tang et al.   CELL

Dynamic Transcription of Distinct Classes of Endogenous Retroviral Elements Marks Specific Populations of Early Human Embryonic Cells

(2015) Jonathan Göke et al.   Cell Stem Cell

Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells

(2015) Dagmar Walter et al.   NATURE

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Early Developmental and Evolutionary Origins of Gene Body DNA Methylation Patterns in Mammalian Placentas

(2015) Diane I. Schroeder et al.   PLoS Genetics

Conditional inactivation of Miwi2 reveals that MIWI2 is only essential for prospermatogonial development in mice

(2014) J Bao et al.   CELL DEATH AND DIFFERENTIATION

Mouse Spermatogenic Stem Cells Continually Interconvert between Equipotent Singly Isolated and Syncytial States

(2014) Kenshiro Hara et al.   Cell Stem Cell

DNMT3L promotes quiescence in postnatal spermatogonial progenitor cells

(2014) H.-F. Liao et al.   DEVELOPMENT

Two waves of de novo methylation during mouse germ cell development

(2014) A. Molaro et al.   GENES & DEVELOPMENT

G9a co-suppresses LINE1 elements in spermatogonia

(2014) Monica Di Giacomo et al.   Epigenetics & Chromatin

One-Step Generation of Mice Carrying Reporter and Conditional Alleles by CRISPR/Cas-Mediated Genome Engineering

(2013) Hui Yang et al.   CELL

High-resolution DNA methylome analysis of primordial germ cells identifies gender-specific reprogramming in mice

(2013) H. Kobayashi et al.   GENOME RESEARCH

Multiple Epigenetic Mechanisms and the piRNA Pathway Enforce LINE1 Silencing during Adult Spermatogenesis

(2013) Monica Di Giacomo et al.   MOLECULAR CELL

Endogenous retroviruses function as species-specific enhancer elements in the placenta

(2013) Edward B Chuong et al.   NATURE GENETICS

Regulation of Lineage Specific DNA Hypomethylation in Mouse Trophectoderm

(2013) Masaaki Oda et al.   PLoS One

Functional Antagonism between Sall4 and Plzf Defines Germline Progenitors

(2012) Robin M. Hobbs et al.   Cell Stem Cell

Global profiling of DNA methylation erasure in mouse primordial germ cells

(2012) S. Guibert et al.   GENOME RESEARCH

TRIM28 repression of retrotransposon-based enhancers is necessary to preserve transcriptional dynamics in embryonic stem cells

(2012) H. M. Rowe et al.   GENOME RESEARCH

The Dynamics of Genome-wide DNA Methylation Reprogramming in Mouse Primordial Germ Cells

(2012) Stefanie Seisenberger et al.   MOLECULAR CELL

Embryonic stem cell potency fluctuates with endogenous retrovirus activity

(2012) Todd S. Macfarlan et al.   NATURE

A unique regulatory phase of DNA methylation in the early mammalian embryo

(2012) Zachary D. Smith et al.   NATURE

DNA Methylation and SETDB1/H3K9me3 Regulate Predominantly Distinct Sets of Genes, Retroelements, and Chimeric Transcripts in mESCs

(2011) Mohammad M. Karimi et al.   Cell Stem Cell

Endogenous retroviruses and neighboring genes are coordinately repressed by LSD1/KDM1A

(2011) Todd S. Macfarlan et al.   GENES & DEVELOPMENT

The endonuclease activity of Mili fuels piRNA amplification that silences LINE1 elements

(2011) Serena De Fazio et al.   NATURE

Full-length transcriptome assembly from RNA-Seq data without a reference genome

(2011) Manfred G Grabherr et al.   NATURE BIOTECHNOLOGY

KAP1 controls endogenous retroviruses in embryonic stem cells

(2010) Helen M. Rowe et al.   NATURE

Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET

(2010) Toshiyuki Matsui et al.   NATURE

Functional Hierarchy and Reversibility Within the Murine Spermatogenic Stem Cell Compartment

(2010) T. Nakagawa et al.   SCIENCE

A genome-wide RNAi screen identifies a new transcriptional module required for self-renewal

(2009) G. Hu et al.   GENES & DEVELOPMENT

From Zygote to Implantation: Morphological and Molecular Dynamics during Embryo Development in the Pig

(2009) O Oestrup et al.   REPRODUCTION IN DOMESTIC ANIMALS

DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes

(2008) S. Kuramochi-Miyagawa et al.   GENES & DEVELOPMENT

Cre recombinase activity specific to postnatal, premeiotic male germ cells in transgenic mice

(2008) Patricia I. Sadate-Ngatchou et al.   GENESIS

A piRNA Pathway Primed by Individual Transposons Is Linked to De Novo DNA Methylation in Mice

(2008) Alexei A. Aravin et al.   MOLECULAR CELL