Bap (Sil1) regulates the molecular chaperone BiP by coupling release of nucleotide and substrate

Nucleotide exchange factors Fes1 and HspBP1 mimic substrate to release misfolded proteins from Hsp70

(2018) Naveen K. C. Gowda et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Nucleotide exchange factors Fes1 and HspBP1 mimic substrate to release misfolded proteins from Hsp70

(2018) Naveen K. C. Gowda et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

An unexpected role for the yeast nucleotide exchange factor Sil1 as a reductant acting on the molecular chaperone BiP

(2017) Kevin D Siegenthaler et al.   eLife

Multidomain structure and correlated dynamics determined by self-consistent FRET networks

(2016) Björn Hellenkamp et al.   NATURE METHODS

BiPPred: Combined sequence- and structure-based prediction of peptide binding to the Hsp70 chaperone BiP

(2016) Markus Schneider et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

BiP and Its Nucleotide Exchange Factors Grp170 and Sil1: Mechanisms of Action and Biological Functions

(2015) Julia Behnke et al.   JOURNAL OF MOLECULAR BIOLOGY

C-terminal amino acids are essential for human heat shock protein 70 dimerization

(2014) Guillaume Marcion et al.   CELL STRESS & CHAPERONES

Molecular Chaperone Functions in Protein Folding and Proteostasis

(2013) Yujin E. Kim et al.   Annual Review of Biochemistry

PTRAJ and CPPTRAJ: Software for Processing and Analysis of Molecular Dynamics Trajectory Data

(2013) Daniel R. Roe et al.   Journal of Chemical Theory and Computation

Structural Studies on the Forward and Reverse Binding Modes of Peptides to the Chaperone DnaK

(2013) Michael Zahn et al.   JOURNAL OF MOLECULAR BIOLOGY

Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP

(2013) Ruifeng Qi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Disentangling Subpopulations in Single-Molecule FRET and ALEX Experiments with Photon Distribution Analysis

(2012) Toma E. Tomov et al.   BIOPHYSICAL JOURNAL

Combining MFD and PIE for Accurate Single-Pair Förster Resonance Energy Transfer Measurements

(2012) Volodymyr Kudryavtsev et al.   CHEMPHYSCHEM

C-terminal Mutations Destabilize SIL1/BAP and Can Cause Marinesco-Sjögren Syndrome

(2012) Jennifer Howes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Conformational Selection in Substrate Recognition by Hsp70 Chaperones

(2012) Moritz Marcinowski et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural analysis of the Sil1–Bip complex reveals the mechanism for Sil1 to function as a nucleotide-exchange factor

(2011) Ming Yan et al.   BIOCHEMICAL JOURNAL

Substrate discrimination of the chaperone BiP by autonomous and cochaperone-regulated conformational transitions

(2011) Moritz Marcinowski et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cdc37-Hsp90 Complexes Are Responsive to Nucleotide-induced Conformational Changes and Binding of Further Cofactors

(2010) Andreas M. Gaiser et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Conformational Dynamics of the Mitochondrial Hsp70 Chaperone

(2010) Koyeli Mapa et al.   MOLECULAR CELL

The HSP70 chaperone machinery: J proteins as drivers of functional specificity

(2010) Harm H. Kampinga et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Biopython: freely available Python tools for computational molecular biology and bioinformatics

(2009) P. J. A. Cock et al.   BIOINFORMATICS

An Unfolded CH1 Domain Controls the Assembly and Secretion of IgG Antibodies

(2009) Matthias J. Feige et al.   MOLECULAR CELL

DynaDock: A new molecular dynamics-based algorithm for protein-peptide docking including receptor flexibility

(2009) Iris Antes   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Life and death of a BiP substrate

(2009) Joel H. Otero et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Probing Protein-Chaperone Interactions with Single-Molecule Fluorescence Spectroscopy

(2008) Frank Hillger et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Swapping Nucleotides, Tuning Hsp70

(2008) Douglas M. Cyr   CELL