Editorial Material
Cell Biology
Paulina Strzyz
Summary: The study shows that tubulin glycylation facilitates sustained sperm motion by regulating the beating of sperm flagella.
NATURE REVIEWS MOLECULAR CELL BIOLOGY
(2021)
Article
Multidisciplinary Sciences
Zhong Peng, Zizhe Hu, Zugang Li, Xiaoxue Zhang, Chaoying Jia, Tianzhi Li, Menghong Dai, Chen Tan, Zhuofei Xu, Bin Wu, Huanchun Chen, Xiangru Wang
Summary: The expanding use of antimicrobials in livestock has led to a rapid increase in antimicrobial resistance (AMR). A large-scale study on AMR in pig farms in China found that E. coli isolates from pigs and their breeding environments in all provinces showed AMR, with 91% of isolates demonstrating multidrug resistance. These isolates showed resistance to last-resort drugs and carried multiple resistance genes, virulence factor-encoding genes, and putative plasmids.
NATURE COMMUNICATIONS
(2022)
Article
Microbiology
Suad Algarni, Jing Han, Dereje D. Gudeta, Bijay K. Khajanchi, Steven C. Ricke, Young Min Kwon, Douglas D. Rhoads, Steven L. Foley
Summary: This study utilized computational approaches to evaluate the diversity and distribution of antimicrobial resistance genes and mobile genetic elements in plasmids. The results showed that resistance genes were widely distributed among different plasmid types, highlighting the potential for gene transmission. This research provides critical insights into the diversity of resistance genes and the dissemination of mobile genetic elements in enteric bacterial pathogens.
FRONTIERS IN MICROBIOLOGY
(2023)
Review
Microbiology
Jiyao Gan, Cristina Giogha, Elizabeth L. Hartland
Summary: Many Gram-negative enteric pathogens have evolved strategies to combat host defence mechanisms by deploying critical bacterial virulence factors to interfere with key host defence pathways. Recent studies have not only contributed to our knowledge of bacterial pathogenesis, but also shed light on the host pathways critical for controlling bacterial infection.
CURRENT OPINION IN MICROBIOLOGY
(2021)
Article
Multidisciplinary Sciences
Anton Spadar, Joao Perdigao, Susana Campino, Taane G. Clark
Summary: A genome-wide association study revealed 29 potential genes associated with liver invasive and hypervirulent phenotype in Klebsiella pneumoniae. However, further large-scale studies involving more sequence types are needed to identify additional biomarkers for hypervirulence.
SCIENTIFIC REPORTS
(2022)
Article
Cell Biology
Yitian Zhou, Qinqin Pu, Jiandong Chen, Guijuan Hao, Rong Gao, Afsar Ali, Ansel Hsiao, Ann M. Stock, Mark Goulian, Jun Zhu
Summary: Pathogenic bacteria can respond rapidly to oxidative stress through reversible thiol oxidation, affecting the activity of regulators and balancing the expression of stress and pathogenesis-related genetic programs.
Article
Biology
Alexandra J. Weisberg, Marilyn Miller, Walt Ream, Niklaus J. Grunwald, Jeff H. Chang
Summary: Members of the agrobacteria-rhizobia complex have multiple and diverse plasmids, which interact with each other and shape the evolution of genomes. This study reveals the interactions and evolutionary histories of oncogenic virulence plasmids, including the discovery of a novel mosaic plasmid.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
(2022)
Article
Biotechnology & Applied Microbiology
A. Yang, W. Li, Z. Tao, H. Ye, Z. Xu, Y. Li, Y. Gao, X. Yan
Summary: This study found that Vibrio harveyi isolates from maricultured species in eastern China displayed significant genetic diversity, varied antimicrobial resistance, and different plasmid profiles. Most isolates from fish hosts carried plasmids, and those with plasmids showed higher virulence to large yellow croaker.
JOURNAL OF APPLIED MICROBIOLOGY
(2021)
Article
Environmental Studies
Lee Bosher, Ksenia Chmutina, Dewald van Niekerk
Summary: The traditional disaster cycle model has been criticized for oversimplifying the complexities of disasters. This paper introduces the Disaster Risk Management Helix as an alternative conceptualization to better address the root causes of vulnerability. The intention is to encourage discussions on moving away from the constraints of the cyclical disaster model and to capture the dynamic nature of disasters and their underlying causes.
DISASTER PREVENTION AND MANAGEMENT
(2021)
Review
Neurosciences
Gonzalo Forno, Albert Llado, Michael Hornberger
Summary: The hippocampus is considered crucial for Alzheimer's disease pathophysiology, but other Papez circuit regions may also be affected, with potential diagnostic value for early AD. Spatial navigation processes within the Papez circuit are gaining recognition for their contribution to AD symptomology.
EUROPEAN JOURNAL OF NEUROSCIENCE
(2021)
Article
Immunology
Valeria Michelacci, Margherita Montalbano Di Filippo, Federica Gigliucci, Silvia Arancia, Paola Chiani, Fabio Minelli, Nancy H. C. Roosens, Sigrid C. J. De Keersmaecker, Bert Bogaerts, Kevin Vanneste, Stefano Morabito
Summary: O26 serogroup of Shiga toxin-producing Escherichia coli (STEC) is a significant cause of Hemolitic Uremic Syndrome (HUS) in children worldwide. The genomic characterization and population structure of O26 STEC strains in Italy reveal differences among different clones and suggest the influence of selective pressure and ecological niches on their evolution.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Food Science & Technology
I. A. Raufu, O. A. Ahmed, A. Aremu, J. A. Ameh, R. E. Timme, R. S. Hendriksen, A. G. Ambali
Summary: Salmonella enterica, a foodborne pathogen of global public health importance, showed low-level resistance against multiple antimicrobial agents in pig farms in Ilorin, Nigeria. The study identified diverse sequence types and existing clusters of Salmonella serovars, emphasizing the need for continuous surveillance programs in Nigeria to curb the spread of resistant strains.
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY
(2021)
Review
Plant Sciences
Alexandra J. Weisberg, Yu wu, Jeff H. Chang, Erh-Min Lai, Chih-Horng Kuo
Summary: Agrobacteria are feared as agricultural pathogens, causing abnormalities and economic damage to plants, but they are also revered in the laboratory for their usefulness as models and tools in biological research. This review synthesizes elegant work on agrobacterial virulence mechanisms and ecology, emphasizing their genomic and plasmid characteristics, and highlights areas for further research.
ANNUAL REVIEW OF PHYTOPATHOLOGY
(2023)
Article
Biotechnology & Applied Microbiology
L. Palaiodimou, S. Fanning, E. M. Fox
Summary: This study identified key genetic markers related to persistence of Listeria strains, such as disinfectant resistance markers and stress tolerance markers. Persistent strains were more likely to contain mutations associated with hypovirulence. The results suggest that no single genetic marker is universally responsible for a strain's ability to persist.
JOURNAL OF APPLIED MICROBIOLOGY
(2021)
Article
Microbiology
Aman Kumar, Regan M. Russell, Mehmet Ali Hoskan, Vanessa Sperandio
Summary: Enteric pathogens such as EHEC and Citrobacter rodentium can sense indole levels within the gut to modulate virulence gene expression, with IsrR serving as a key regulator in discriminating between microbiota-derived and self-produced indole signals. This fine-tuning of gene expression allows pathogens to establish infection in the complex intestinal environment.
