TDP-43 gains function due to perturbed autoregulation in a Tardbp knock-in mouse model of ALS-FTD
出版年份 2018 全文链接
标题
TDP-43 gains function due to perturbed autoregulation in a Tardbp knock-in mouse model of ALS-FTD
作者
关键词
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出版物
NATURE NEUROSCIENCE
Volume 21, Issue 4, Pages 552-563
出版商
Springer Nature
发表日期
2018-04-04
DOI
10.1038/s41593-018-0113-5
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- (2017) Eric Swanson et al. JOURNAL OF ALZHEIMERS DISEASE
- Therapeutic reduction of ataxin-2 extends lifespan and reduces pathology in TDP-43 mice
- (2017) Lindsay A. Becker et al. NATURE
- NEK1mutations in familial amyotrophic lateral sclerosis
- (2016) David Brenner et al. BRAIN
- Prefrontal Parvalbumin Neurons in Control of Attention
- (2016) Hoseok Kim et al. CELL
- Co-immunoprecipitation with Tau Isoform-specific Antibodies Reveals Distinct Protein Interactions and Highlights a Putative Role for 2N Tau in Disease
- (2016) Chang Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The frontotemporal dementia-motor neuron disease continuum
- (2016) James R Burrell et al. LANCET
- NEK1 variants confer susceptibility to amyotrophic lateral sclerosis
- (2016) Kevin P Kenna et al. NATURE GENETICS
- Increased cytoplasmicTARDBPmRNA in affected spinal motor neurons in ALS caused by abnormal autoregulation of TDP-43
- (2016) Akihide Koyama et al. NUCLEIC ACIDS RESEARCH
- Assessment of Eating Behavior Disturbance and Associated Neural Networks in Frontotemporal Dementia
- (2016) Rebekah M. Ahmed et al. JAMA Neurology
- Pathological tau deposition in Motor Neurone Disease and frontotemporal lobar degeneration associated with TDP-43 proteinopathy
- (2016) Roya Behrouzi et al. Acta Neuropathologica Communications
- Age-Dependent TDP-43-Mediated Motor Neuron Degeneration Requires GSK3, hat-trick, and xmas-2
- (2015) Jemeen Sreedharan et al. CURRENT BIOLOGY
- Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia
- (2015) Axel Freischmidt et al. NATURE NEUROSCIENCE
- Motivational assessment of mice using the touchscreen operant testing system: effects of dopaminergic drugs
- (2015) Christopher J. Heath et al. PSYCHOPHARMACOLOGY
- Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways
- (2015) E. T. Cirulli et al. SCIENCE
- Mutations in the Matrin 3 gene cause familial amyotrophic lateral sclerosis
- (2014) Janel O Johnson et al. NATURE NEUROSCIENCE
- Genetic architecture of ALS in Sardinia
- (2014) Giuseppe Borghero et al. NEUROBIOLOGY OF AGING
- ERBB4 Mutations that Disrupt the Neuregulin-ErbB4 Pathway Cause Amyotrophic Lateral Sclerosis Type 19
- (2013) Yuji Takahashi et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Myelin management by the 18.5-kDa and 21.5-kDa classic myelin basic protein isoforms
- (2013) George Harauz et al. JOURNAL OF NEUROCHEMISTRY
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- (2013) C. Romberg et al. JOURNAL OF NEUROSCIENCE
- Degeneration and impaired regeneration of gray matter oligodendrocytes in amyotrophic lateral sclerosis
- (2013) Shin H Kang et al. NATURE NEUROSCIENCE
- The touchscreen operant platform for assessing executive function in rats and mice
- (2013) Adam C Mar et al. Nature Protocols
- ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43
- (2013) E. S. Arnold et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Oral Treatment Targeting the Unfolded Protein Response Prevents Neurodegeneration and Clinical Disease in Prion-Infected Mice
- (2013) J. A. Moreno et al. Science Translational Medicine
- The Role of MuSK in Synapse Formation and Neuromuscular Disease
- (2013) S. J. Burden et al. Cold Spring Harbor Perspectives in Biology
- MAPT expression and splicing is differentially regulated by brain region: relation to genotype and implication for tauopathies
- (2012) Daniah Trabzuni et al. HUMAN MOLECULAR GENETICS
- Targeted Depletion of TDP-43 Expression in the Spinal Cord Motor Neurons Leads to the Development of Amyotrophic Lateral Sclerosis-like Phenotypes in Mice
- (2012) Lien-Szu Wu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans
- (2012) Annelies Van Hoecke et al. NATURE MEDICINE
- Drug Screening for ALS Using Patient-Specific Induced Pluripotent Stem Cells
- (2012) N. Egawa et al. Science Translational Medicine
- SQSTM1 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis
- (2011) Faisal Fecto ARCHIVES OF NEUROLOGY
- Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43
- (2011) Magdalini Polymenidou et al. NATURE NEUROSCIENCE
- Characterizing the RNA targets and position-dependent splicing regulation by TDP-43
- (2011) James R Tollervey et al. NATURE NEUROSCIENCE
- Nuclear import impairment causes cytoplasmic trans-activation response DNA-binding protein accumulation and is associated with frontotemporal lobar degeneration
- (2010) Agnes L. Nishimura et al. BRAIN
- TDP-43 regulates its mRNA levels through a negative feedback loop
- (2010) Youhna M Ayala et al. EMBO JOURNAL
- Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS
- (2010) Andrew C. Elden et al. NATURE
- Automated home-cage behavioural phenotyping of mice
- (2010) Hueihan Jhuang et al. Nature Communications
- TARDBPmutations in motoneuron disease with frontotemporal lobar degeneration
- (2009) Lina Benajiba et al. ANNALS OF NEUROLOGY
- TDP-43 Is Intrinsically Aggregation-prone, and Amyotrophic Lateral Sclerosis-linked Mutations Accelerate Aggregation and Increase Toxicity
- (2009) Brian S. Johnson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Reduced expression of the Kinesin-Associated Protein 3 (KIFAP3) gene increases survival in sporadic amyotrophic lateral sclerosis
- (2009) J. E. Landers et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Marble burying reflects a repetitive and perseverative behavior more than novelty-induced anxiety
- (2009) Alexia Thomas et al. PSYCHOPHARMACOLOGY
- TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis
- (2008) J. Sreedharan et al. SCIENCE
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