Pharmacokinetic and pharmacometabolomic study of pirfenidone in normal mouse tissues using high mass resolution MALDI-FTICR-mass spectrometry imaging

A Phase 3 Trial of Pirfenidone in Patients with Idiopathic Pulmonary Fibrosis

(2014) Talmadge E. King et al.   NEW ENGLAND JOURNAL OF MEDICINE

High-resolution metabolite imaging of light and dark treated retina using MALDI-FTICR mass spectrometry

(2014) Na Sun et al.   PROTEOMICS

Possible Involvement of Pirfenidone Metabolites in the Antifibrotic Action of a Therapy for Idiopathic Pulmonary Fibrosis

(2013) Kohei Togami et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Analysis of Tissue Specimens by Matrix-Assisted Laser Desorption/Ionization Imaging Mass Spectrometry in Biological and Clinical Research

(2013) Jeremy L. Norris et al.   CHEMICAL REVIEWS

Pharmacometabolomics Reveals Racial Differences in Response to Atenolol Treatment

(2013) William R. Wikoff et al.   PLoS One

Identifying Tissue-Specific Signal Variation in MALDI Mass Spectrometric Imaging by Use of an Internal Standard

(2012) David A. Pirman et al.   ANALYTICAL CHEMISTRY

Novel mass spectrometry imaging software assisting labeled normalization and quantitation of drugs and neuropeptides directly in tissue sections

(2012) Patrik Källback et al.   Journal of Proteomics

New cellular and molecular mechanisms of lung injury and fibrosis in idiopathic pulmonary fibrosis

(2012) Isis E Fernandez et al.   LANCET

An Official ATS/ERS/JRS/ALAT Statement: Idiopathic Pulmonary Fibrosis: Evidence-based Guidelines for Diagnosis and Management

(2011) Ganesh Raghu et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Mass spectrometry imaging with high resolution in mass and space (HR2 MSI) for reliable investigation of drug compound distributions on the cellular level

(2011) Andreas Römpp et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

MALDI imaging mass spectrometry for direct tissue analysis: technological advancements and recent applications

(2011) Benjamin Balluff et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Idiopathic pulmonary fibrosis

(2011) Talmadge E King et al.   LANCET

Pirfenidone in patients with idiopathic pulmonary fibrosis (CAPACITY): two randomised trials

(2011) Paul W Noble et al.   LANCET

MALDI imaging mass spectrometry: bridging biology and chemistry in drug development

(2011) Stephen Castellino et al.   Bioanalysis

Ultrahighly Sensitive in Situ Metabolomic Imaging for Visualizing Spatiotemporal Metabolic Behaviors

(2010) Daisuke Miura et al.   ANALYTICAL CHEMISTRY

Imaging Mass Spectrometry Data Reduction: Automated Feature Identification and Extraction

(2010) Liam A. McDonnell et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Highly Sensitive Matrix-Assisted Laser Desorption Ionization-Mass Spectrometry for High-Throughput Metabolic Profiling

(2009) Daisuke Miura et al.   ANALYTICAL CHEMISTRY

Pirfenidone inhibits carbon tetrachloride- and albumin complex-induced liver fibrosis in rodents by preventing activation of hepatic stellate cells

(2009) Xin-Yan Zhao et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

MALDI-FTICR Imaging Mass Spectrometry of Drugs and Metabolites in Tissue

(2008) Dale S. Cornett et al.   ANALYTICAL CHEMISTRY

Pharmacokinetics and metabolism of intravenous pirfenidone in sheep

(2008) Michael L. Bruss et al.   BIOPHARMACEUTICS & DRUG DISPOSITION

MALDI imaging mass spectrometry for direct tissue analysis: a new frontier for molecular histology

(2008) Axel Walch et al.   HISTOCHEMISTRY AND CELL BIOLOGY