Genetically engineered cerebral organoids model brain tumor formation

Hacking macrophage-associated immunosuppression for regulating glioblastoma angiogenesis

(2018) Xin Cui et al.   BIOMATERIALS

Zika virus has oncolytic activity against glioblastoma stem cells

(2017) Zhe Zhu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Fused cerebral organoids model interactions between brain regions

(2017) Joshua A Bagley et al.   NATURE METHODS

An Organoid-Based Model of Cortical Development Identifies Non-Cell-Autonomous Defects in Wnt Signaling Contributing to Miller-Dieker Syndrome

(2017) Vira Iefremova et al.   Cell Reports

Modeling and Targeting MYC Genes in Childhood Brain Tumors

(2017) Sonja Hutter et al.   Genes

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

(2016) David N. Louis et al.   ACTA NEUROPATHOLOGICA

Organoids as Models for Neoplastic Transformation

(2016) James T. Neal et al.   Annual Review of Pathology-Mechanisms of Disease

A Three-Dimensional Organoid Culture System Derived from Human Glioblastomas Recapitulates the Hypoxic Gradients and Cancer Stem Cell Heterogeneity of Tumors Found In Vivo

(2016) Christopher G. Hubert et al.   CANCER RESEARCH

Epigenetic Activation of WNT5A Drives Glioblastoma Stem Cell Differentiation and Invasive Growth

(2016) Baoli Hu et al.   CELL

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

(2016) Dominik Sturm et al.   CELL

Stem Cell Models of Human Brain Development

(2016) Iva Kelava et al.   Cell Stem Cell

An Ectopic Network of Transcription Factors Regulated by Hippo Signaling Drives Growth and Invasion of a Malignant Tumor Model

(2016) Mardelle Atkins et al.   CURRENT BIOLOGY

Efficient derivation of microglia-like cells from human pluripotent stem cells

(2016) Julien Muffat et al.   NATURE MEDICINE

CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2009–2013

(2016) Quinn T. Ostrom et al.   NEURO-ONCOLOGY

Epithelial-mesenchymal transition in glioblastoma progression

(2016) YASUO IWADATE   Oncology Letters

Mechanisms regulating glioma invasion

(2015) Ivy Paw et al.   CANCER LETTERS

FOXG1-Dependent Dysregulation of GABA/Glutamate Neuron Differentiation in Autism Spectrum Disorders

(2015) Jessica Mariani et al.   CELL

Human stem cell-based disease modeling: prospects and challenges

(2015) Joshua Z Johnson et al.   CURRENT OPINION IN CELL BIOLOGY

Activation of Multiple ERBB Family Receptors Mediates Glioblastoma Cancer Stem-like Cell Resistance to EGFR-Targeted Inhibition

(2015) Paul A. Clark et al.   NEOPLASIA

Primate-specific endogenous retrovirus-driven transcription defines naive-like stem cells

(2014) Jichang Wang et al.   NATURE

Organogenesis in a dish: Modeling development and disease using organoid technologies

(2014) M. A. Lancaster et al.   SCIENCE

An integral program for tissue renewal and regeneration: Wnt signaling and stem cell control

(2014) H. Clevers et al.   SCIENCE

The Somatic Genomic Landscape of Glioblastoma

(2013) Cameron W. Brennan et al.   CELL

Cerebral organoids model human brain development and microcephaly

(2013) Madeline A. Lancaster et al.   NATURE

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

WNT/β-catenin pathway activation in Myc immortalised cerebellar progenitor cells inhibits neuronal differentiation and generates tumours resembling medulloblastoma

(2012) H A Rogers et al.   BRITISH JOURNAL OF CANCER

Malignant Glioma: Lessons from Genomics, Mouse Models, and Stem Cells

(2012) Jian Chen et al.   CELL

Differential expression of HIF-1 in glioblastoma multiforme and anaplastic astrocytoma

(2012) ARNULF MAYER et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

In vivo models of primary brain tumors: pitfalls and perspectives

(2012) P. C. Huszthy et al.   NEURO-ONCOLOGY

Development and Evolution of the Human Neocortex

(2011) Jan H. Lui et al.   CELL

CD99 inhibits neural differentiation of human Ewing sarcoma cells and thereby contributes to oncogenesis

(2010) Anna Rocchi et al.   JOURNAL OF CLINICAL INVESTIGATION

Subtypes of medulloblastoma have distinct developmental origins

(2010) Paul Gibson et al.   NATURE

The Genetic Landscape of the Childhood Cancer Medulloblastoma

(2010) D. W. Parsons et al.   SCIENCE

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

(2009) Toshiro Sato et al.   NATURE

Molecular evolution of a novel hyperactive Sleeping Beauty transposase enables robust stable gene transfer in vertebrates

(2009) Lajos Mátés et al.   NATURE GENETICS

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Pten Haploinsufficiency Accelerates Formation of High-Grade Astrocytomas

(2008) C.-H. Kwon et al.   CANCER RESEARCH

p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation

(2008) Hongwu Zheng et al.   NATURE

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE

c-Myc and β-catenin cooperate with loss of p53 to generate multiple members of the primitive neuroectodermal tumor family in mice

(2008) H Momota et al.   ONCOGENE