Metastatic cancers promote cachexia through ZIP14 upregulation in skeletal muscle

The Multiple Faces of the Metal Transporter ZIP14 (SLC39A14)

(2018) Tolunay B Aydemir et al.   JOURNAL OF NUTRITION

Cancer-associated cachexia

(2018) Vickie E. Baracos et al.   Nature Reviews Disease Primers

Myofibril breakdown during atrophy is a delayed response requiring the transcription factor PAX4 and desmin depolymerization

(2017) Alexandra Volodin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extracellular Vesicles in Cancer: Cell-to-Cell Mediators of Metastasis

(2016) Annette Becker et al.   CANCER CELL

Blockade of Metallothioneins 1 and 2 Increases Skeletal Muscle Mass and Strength

(2016) Serge Summermatter et al.   MOLECULAR AND CELLULAR BIOLOGY

Metastatic colonization by circulating tumour cells

(2016) Joan Massagué et al.   NATURE

Impaired regeneration: A role for the muscle microenvironment in cancer cachexia

(2016) Erin E. Talbert et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Protein breakdown in cancer cachexia

(2016) Marco Sandri   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Experimental cancer cachexia: Evolving strategies for getting closer to the human scenario

(2016) Fabio Penna et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Rapid, scalable, and low-cost purification of recombinant adeno-associated virus produced by baculovirus expression vector system

(2016) Pierre-Olivier Buclez et al.   Molecular Therapy-Methods & Clinical Development

SLC39A14 Is Required for the Development of Hepatocellular Iron Overload in Murine Models of Hereditary Hemochromatosis

(2015) Supak Jenkitkasemwong et al.   Cell Metabolism

Intrinsic and extrinsic mechanisms regulating satellite cell function

(2015) N. A. Dumont et al.   DEVELOPMENT

Excess TGF-β mediates muscle weakness associated with bone metastases in mice

(2015) David L Waning et al.   NATURE MEDICINE

Muscle wasting in disease: molecular mechanisms and promising therapies

(2015) Shenhav Cohen et al.   NATURE REVIEWS DRUG DISCOVERY

Cardiac and skeletal muscles show molecularly distinct responses to cancer cachexia

(2015) Angie M. Y. Shum et al.   PHYSIOLOGICAL GENOMICS

The Molecular Signatures Database Hallmark Gene Set Collection

(2015) Arthur Liberzon et al.   Cell Systems

Loss of Lkb1 and Pten Leads to Lung Squamous Cell Carcinoma with Elevated PD-L1 Expression

(2014) Chunxiao Xu et al.   CANCER CELL

The tumour-induced systemic environment as a critical regulator of cancer progression and metastasis

(2014) Sandra S. McAllister et al.   NATURE CELL BIOLOGY

Requirement of MEF2A, C, and D for skeletal muscle regeneration

(2014) N. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diaphragm and ventilatory dysfunction during cancer cachexia

(2013) Brandon M. Roberts et al.   FASEB JOURNAL

Mechanisms regulating skeletal muscle growth and atrophy

(2013) Stefano Schiaffino et al.   FEBS Journal

NF-κB–mediated Pax7 dysregulation in the muscle microenvironment promotes cancer cachexia

(2013) Wei A. He et al.   JOURNAL OF CLINICAL INVESTIGATION

Mouse models for lung cancer

(2013) Min-chul Kwon et al.   Molecular Oncology

A Drug Repositioning Approach Identifies Tricyclic Antidepressants as Inhibitors of Small Cell Lung Cancer and Other Neuroendocrine Tumors

(2013) N. S. Jahchan et al.   Cancer Discovery

A CXCL1 Paracrine Network Links Cancer Chemoresistance and Metastasis

(2012) Swarnali Acharyya et al.   CELL

Cancer Cachexia: Mediators, Signaling, and Metabolic Pathways

(2012) Kenneth C.H. Fearon et al.   Cell Metabolism

Global secretome analysis identifies novel mediators of bone metastasis

(2012) Mario Andres Blanco et al.   CELL RESEARCH

Understanding the mechanisms and treatment options in cancer cachexia

(2012) Kenneth Fearon et al.   Nature Reviews Clinical Oncology

Muscle actin is polyubiquitinylated in vitro and in vivo and targeted for breakdown by the E3 ligase MuRF1

(2011) Cécile Polge et al.   FASEB JOURNAL

Myosin heavy chain is not selectively decreased in murine cancer cachexia

(2011) Pippa F. Cosper et al.   INTERNATIONAL JOURNAL OF CANCER

The Zinc Transporter SLC39A14/ZIP14 Controls G-Protein Coupled Receptor-Mediated Signaling Required for Systemic Growth

(2011) Shintaro Hojyo et al.   PLoS One

STAT3 Activation in Skeletal Muscle Links Muscle Wasting and the Acute Phase Response in Cancer Cachexia

(2011) Andrea Bonetto et al.   PLoS One

The role of zinc in the anti-tumour and anti-cachectic activity of D-myo-inositol 1,2,6-triphosphate

(2010) S T Russell et al.   BRITISH JOURNAL OF CANCER

Signaling pathways perturbing muscle mass

(2010) David J Glass   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Muscle Wasting and Impaired Myogenesis in Tumor Bearing Mice Are Prevented by ERK Inhibition

(2010) Fabio Penna et al.   PLoS One

Systemic zinc redistribution and dyshomeostasis in cancer cachexia

(2010) Pontus M. A. Siren et al.   Journal of Cachexia Sarcopenia and Muscle

Metalloproteomes: A Bioinformatic Approach

(2009) Claudia Andreini et al.   ACCOUNTS OF CHEMICAL RESEARCH

Mammalian Zinc Transporters: Nutritional and Physiologic Regulation

(2009) Louis A. Lichten et al.   Annual Review of Nutrition

WNT/TCF Signaling through LEF1 and HOXB9 Mediates Lung Adenocarcinoma Metastasis

(2009) Don X. Nguyen et al.   CELL

During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation

(2009) Shenhav Cohen et al.   JOURNAL OF CELL BIOLOGY

Conditional mouse lung cancer models using adenoviral or lentiviral delivery of Cre recombinase

(2009) Michel DuPage et al.   Nature Protocols

Mechanisms of Muscle Degeneration, Regeneration, and Repair in the Muscular Dystrophies

(2008) Gregory Q. Wallace et al.   Annual Review of Physiology

Cancer cachexia: Developing multimodal therapy for a multidimensional problem

(2008) K.C.H. Fearon   EUROPEAN JOURNAL OF CANCER