Article
Cell Biology
Jessica J. A. Hummel, Casper C. Hoogenraad
Summary: In this study, the authors systematically investigated the selectivity and regulation of KIF1A-driven transport of different types of vesicles, emphasizing the importance of phosphorylation for vesicle binding and the role of specific adaptors in achieving cargo specificity. They propose a model where motor dimerization, posttranslational modifications, and specific adaptors regulate selective KIF1A cargo trafficking.
JOURNAL OF CELL BIOLOGY
(2021)
Article
Materials Science, Multidisciplinary
Danielle Scheepers, Anna Casimiro, Zandrie Borneman, Kitty Nijmeijer
Summary: In this study, the concept of chaotropicity of polycations and their counterions was introduced and their effects on membrane performance were investigated. It was found that higher chaotropicity resulted in more mass adsorption and higher pure water permeability.
ACS APPLIED POLYMER MATERIALS
(2023)
Article
Biology
James Cushway, Liam Murphy, J. Geoffrey Chase, Geoffrey M. Shaw, Thomas Desaive
Summary: Mechanical ventilation, especially when using high positive end-expiratory pressure, has detrimental effects on the cardiovascular system. Stressed blood volume, which is an index of fluid responsiveness, can potentially be used as a diagnostic tool. Therefore, optimizing both the pulmonary and cardiovascular state is important for guiding the use of positive end-expiratory pressure.
COMPUTERS IN BIOLOGY AND MEDICINE
(2022)
Article
Chemistry, Analytical
Tingting Han, Andrey Kalinichev, Zekra Mousavi, Konstantin N. Mikhelson, Johan Bobacka
Summary: This work characterized the potentiometric response of solid-contact ion-selective electrodes with thin-layer ion-selective membranes. The anomalous increase in potential at low concentrations of the primary potassium ion was found to be influenced by the solid-contact material, thickness of the membrane, and timescale of the measurement. It was concluded that the anomalous response is a characteristic feature of these electrodes and can be used as a diagnostic tool.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Nanoscience & Nanotechnology
Purna K. Boruah, Priyakshree Borthakur, Gayatri Neog, Benjamin Le Ouay, Nazim Uddin Afzal, Prasenjit Manna, Manash R. Das
Summary: This article describes the synthesis of porous 3D nitrogen-doped crumpled graphene nanoparticles (CGNPs) and their use as a platform for the sensitive detection of dopamine (DA) in complex biological media such as blood serum. The CGNPs were prepared by doping graphene oxide (GO) using ammonium hydroxide in a hydrothermal treatment. The system selectively detected DA with a limit of detection of 1.15 μM and a linearity range of 1 to 20 μM, and it showed good selectivity in the presence of various interfering species and in human blood serum.
ACS APPLIED NANO MATERIALS
(2023)
Article
Chemistry, Analytical
Yujie Liu, Gaston A. Crespo, Maria Cuartero
Summary: The study presents a spectroelectrochemical sensing method for potassium ion detection in nanomolar, micromolar, and millimolar ranges using the same ion-selective electrode. The method offers a wide response range and is suitable for various samples and ion analytes.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Yan Su, Ting Liu, Caiqiao Song, Aiqiao Fan, Nan Zhu, Bingbing Sun, Cheng Yang
Summary: A solid-contact ion-selective electrode (SC-ISE) using MoS2/Fe3O4 composites as the ion-to-electron transducer was developed to determine serum K+ with high sensitivity and stability. The electrode showed a Nernst response with a low detection limit, resistance to interference, and good potential reproducibility and long-term stability.
Article
Chemistry, Multidisciplinary
Tongtai Ji, Chunyan Zhang, Xianghui Xiao, Ying Wang, Daxian Cao, Arturas Adomkevicius, Yuyue Zhao, Xiao Sun, Kun Fu, Hongli Zhu
Summary: A bifunctional ion-selective layer is developed by combining nanoporous boron nitride (PBN) with ion exchange groups from Nafion to achieve high ion conductivity and selectivity. A template-free method is used to synthesize flake-like PBN, which is then enmeshed with Nafion resin and coated onto a porous polyetherimide membrane. The double-layer membrane exhibits excellent ion selectivity and conductivity and shows promising application in vanadium flow batteries.
Article
Chemistry, Physical
Xiaomei Huo, Longhua Xu, Keyu Xie, Kun Zhang, Jing Li, Donghui Wang, Kaiqian Shu
Summary: A versatile Zn-based laponite (Zn-LT) interface is constructed for uniform and rapid Zn deposition in aqueous zinc-ion batteries (AZIBs), resulting in high Coulombic efficiency and long lifespan.
ADVANCED ENERGY MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Jiayun Wen, Tengrui Wang, Chao Wang, Yiming Dai, Zhenyou Song, Xuyang Liu, Qian Yu, Xueying Zheng, Jiwei Ma, Wei Luo, Yunhui Huang
Summary: An interfacial engineering strategy between the garnet electrolyte and copper foil is proposed for stable and efficient anode-free solid-state batteries. The strategy utilizes the high Li ion conductivity, interfacial self-adaption ability, and regulated Li deposition, leading to stable long-term operation and outstanding capacity retention.
ADVANCED MATERIALS
(2023)
Article
Chemistry, Analytical
Longbin Xu, Shiyu Gan, Lijie Zhong, Zhonghui Sun, Yitian Tang, Tingting Han, Kanglong Lin, Chunxian Liao, Dequan He, Yingming Ma, Wei Wang, Li Niu
Summary: The conductive metal organic framework (MOF) demonstrates efficient electron transfer ability and ion recognition. An ISM-free SC-ISE based on this conductive MOF shows high sensitivity and short response time for Cu2+ detection, offering normal potentiometric responses even under short conditioning time.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2022)
Review
Chemistry, Analytical
Celeste R. Rousseau, Philippe Buhlmann
Summary: Research in recent years has focused on the development of solid-contact ISEs for calibration-free measurements in long-term, in situ analysis. This review discusses the definition of calibration-free usage and relevant literature, with a focus on different mechanisms of ion-to-electron signal transduction and different types of transduction modes.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Nannan Zhang, Shuo Huang, Zishun Yuan, Jiacai Zhu, Zifang Zhao, Zhiqiang Niu
Summary: In this study, an ultrathin and uniform MXene layer was assembled on the surface of zinc anodes using an in situ spontaneously reducing/assembling strategy. The integrated MXene layer reduced the zinc nucleation energy barrier and provided a more uniformly distributed electric field, resulting in low voltage hysteresis and excellent cycling stability with dendrite-free behaviors in zinc-ion batteries.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Physical
Qing Wen, Hao Fu, Ying-de Huang, Ru-de Cui, He-zhang Chen, Rui-han Ji, Lin-bo Tang, Cheng Yan, Jing Mao, Ke-hua Dai, Qing Wu, Xia-hui Zhang, Jun-chao Zheng
Summary: Due to their exceptional safety profile and cost-effectiveness, aqueous zinc-ion batteries have attracted considerable attention as promising energy storage systems. This study proposes an ultrasonic coating method to construct a thin, zincophilic and uniform layer of zinc tartrate on the zinc anode, effectively inhibiting corrosion and promoting uniform deposition of zinc.
Article
Chemistry, Physical
Marijana Hercigonja, Branislav Milovanovic, Mihajlo Etinski, Milena Petkovic
Summary: Deviation of sodium and potassium concentrations from their optimal values in living organisms is associated with severe health conditions. Thus, sensitive sensors are required for the precise determination of these ions in blood samples. Besides, excess sodium and potassium should be removed from drinking water. In this study, the role of solvent molecules in the selectivity of crown ethers toward specific cations is analyzed and highlighted.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Review
Chemistry, Physical
Alan Sam, Remco Hartkamp, Sridhar Kumar Kannam, Jeetu S. Babu, Sarith P. Sathian, Peter J. Daivis, B. D. Todd
Summary: The mass transport properties of carbon nanotubes, particularly the rapid transport of water through them, have attracted significant attention. Research has focused on understanding the mechanisms of water flow in contact with CNTs, particularly slip and flow rates, with confirmed enhancements in water flow rate through graphitic nanoconfinement. However, discrepancies in quantitative agreement and incomplete knowledge of water transport mechanisms at nanoscale regimes are hindering the integration of CNTs in various nanofluidic applications. Further studies are needed to address the sources of disparities in water flow rate and suggest future research directions.
MOLECULAR SIMULATION
(2021)
Article
Chemistry, Physical
Rong Fan, Parsa Habibi, Johan T. Padding, Remco Hartkamp
Summary: In heterogeneous catalysis, the reactivity and selectivity are not only governed by the chemical processes on catalytic surfaces, but also influenced by physical transport phenomena in the fluid. Modeling heterogeneous catalytic reactors is a challenge due to the wide range of time and length scales involved, especially for complex surface reactions. The Stochastic Rotation Dynamics (SRD) method, as a particle-based mesoscale method, is suitable for studying problems that involve microscale effects and fluid transport phenomena. In this study, the authors demonstrate how to simulate heterogeneous catalytic reactors by coupling SRD fluid with a catalytic surface, where complex surface reactions are explicitly modeled. The potential of the method is shown by simulating a three-step reaction mechanism with reactant dissociation.
JOURNAL OF CHEMICAL PHYSICS
(2022)
Article
Physics, Multidisciplinary
Max F. Dopke, Fenna Westerbaan van der Meij, Benoit Coasne, Remco Hartkamp
Summary: By simulating surface protolysis, we have discovered that this chemical event strongly impacts the EDL and electrokinetic properties, resulting in significant changes in zeta potential and electro-osmotic flow.
PHYSICAL REVIEW LETTERS
(2022)
Article
Chemistry, Physical
Ahmadreza Rahbari, Remco Hartkamp, Othonas A. Moultos, Albert Bos, Leo J. P. van den Broeke, Mahinder Ramdin, David Dubbeldam, Alexey Lyulin, Thijs J. H. Vlugt
Summary: In this study, a classical all-atom model is used to compute the electro-osmotic drag (EOD) coefficient of water and thermodynamic properties from molecular dynamics simulations for Nafion membranes. The model captures the vehicular mechanism of proton transfer well, but overestimates the EOD coefficient at higher water contents (lambda = 20).
JOURNAL OF PHYSICAL CHEMISTRY C
(2022)
Article
Physics, Applied
Kensaku Chida, Akira Fujiwara, Katsuhiko Nishiguchi
Summary: In this study, we measured the thermoelectric effect in a nanometer-scale silicon dot using electron counting statistics. The random motion of single electrons between the dot and silicon nanowire was observed to determine temperature and voltage at the dot.
APPLIED PHYSICS LETTERS
(2022)
Article
Biophysics
S. Li, Y. Coffinier, C. Lagadec, F. Cleri, K. Nishiguchi, A. Fujiwara, T. Fujii, S-H Kim, N. Clement
Summary: In this study, 20-nm-thick nanopillars were used to overcome the downward force issue caused by cells on bioelectrochemical sensors. The experiments and simulations showed that suspending cells a few nanometers above the electrode surface allowed redox-labelled DNA aptamer probes to freely move and interact with target membrane proteins. This novel nanosupported electrochemical DNA cell sensor scheme provides new opportunities for the design of all-electrical sensors using redox-labelled probes.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Physics, Applied
Katsuhiko Nishiguchi, Hiroshi Yamaguchi, Akira Fujiwara, Herre S. J. van der Zant, Gary A. Steele
Summary: We have demonstrated charge detection with single-electron resolution at high readout frequency using a silicon field-effect transistor integrated with double resonant circuits. The transistor, with a channel width of 10 nm, can detect a single electron at room temperature. The transistor is connected to resonant circuits composed of coupled inductors and capacitors, providing two resonance frequencies. By driving the transistor with a carrier signal at the lower resonance frequency, a small signal applied to the transistor's gate modulates the resonance condition, resulting in a reflected signal appearing near the higher resonance frequency. This operation allows for charge detection with a single-electron resolution of 3 x 10(-3) e/Hz(0.5) and a readout frequency of 200 MHz at room temperature.
APPLIED PHYSICS LETTERS
(2023)
Article
Physics, Applied
Katsuhiko Nishiguchi, Hiroshi Yamaguchi, Akira Fujiwara
Summary: We detect the mechanical oscillations of a nanoelectromechanical system (NEMS) composed of a multilayer-graphene (MLG) membrane using a Si field-effect transistor (FET) and a microwave probe connected to double-resonant circuits. The mechanical oscillations of the MLG membrane as it functions as the gate of the FET are monitored through modulation of the FET's impedance. This rf-signal-driven readout at 340 MHz allows for highly sensitive and functional sensors for small mass and quantum mechanics as well as timing devices.
PHYSICAL REVIEW APPLIED
(2023)
Article
Chemistry, Physical
Esaar Naeem Butt, Johan T. Padding, Remco Hartkamp
Summary: The electrochemical reduction of CO2 is influenced by reaction conditions near the electrode surface, including electric double layer formation and steric effects. Existing models disregard these effects, leading to an incomplete understanding of the local electrode environment. This study presents a modified modeling approach that accurately describes concentration profiles and experimental results. The model is also applicable to systems operating at elevated CO2 pressures. By incorporating the theory of the double layer, a mechanistic understanding of the CO2 reduction process is achieved.
SUSTAINABLE ENERGY & FUELS
(2022)
Article
Physics, Applied
Kensaku Chida, Akira Fujiwara, Katsuhiko Nishiguchi
Summary: This study converted Gaussian-distributed voltage noise into the non-equilibrium free energy of a nanometer-scale dot connected to an electron reservoir. By analyzing electron counting statistics, the energy transported into the dot as well as changes in internal energy and effective temperature were quantitatively analyzed in the noise-induced non-equilibrium steady state. It was confirmed that the rectification effect caused by the asymmetry with respect to electron motion direction is the origin of the increase in internal energy of the dot. The information obtained in this study clarifies the relationship between the non-equilibrium dynamics of a nanodevice and applied noise, providing a means to evaluate device operation using noise as a resource.
APPLIED PHYSICS LETTERS
(2023)
Review
Chemistry, Multidisciplinary
Vikram Korede, Nagaraj Nagalingam, Frederico Marques Penha, Noah van der Linden, Johan T. Padding, Remco Hartkamp, Huseyin Burak Eral
Summary: Crystallization is widely present in nature and industrial practices, but our control over the process is incomplete. This limits our ability to engineer crystalline products and hinders progress towards a sustainable circular economy. Laser-induced crystallization approaches show promise in manipulating crystallization using light-material interactions. In this review, we discuss various mechanisms and experimental setups for laser-induced nucleation and crystallization, emphasizing interdisciplinary exchange of ideas.
CRYSTAL GROWTH & DESIGN
(2023)
Article
Physics, Multidisciplinary
Toshiaki Hayashi, Yasuhiro Tokura, Katsuhiko Nishiguchi
Summary: Variable-range hopping transport is studied from a new perspective, focusing on the statistical properties of voltage potential at different sites. By calculating the deviations in the voltage potentials using rate equations, it is found that there are two temperature regimes: nearest-neighbor hopping at high temperatures and variable-range hopping at low temperatures. The temperature dependence of the correlation length confirms the development of long-range order in the variable-range hopping regime.
JOURNAL OF THE PHYSICAL SOCIETY OF JAPAN
(2023)
Article
Engineering, Electrical & Electronic
Nagaraj Nagalingam, Aswin Raghunathan, Vikram Korede, Edwin F. J. Overmars, Shih-Te Hung, Remco Hartkamp, Johan T. Padding, Carlas S. Smith, Huseyin Burak Eral
Summary: Optofluidic devices have greatly advanced the manipulation and transport of fluid at small scales. In this study, we present a specialized optical setup for investigating laser-induced cavitation within microchannels. By evaporating a dye-laced solution with a tightly focused laser beam, we can create a microbubble and track its interface using high-speed microscopy and digital image analysis. Additionally, we demonstrate how this system can be adapted for fluid flow analysis through fluorescence-Particle Image Velocimetry (PIV) technique. We also provide guidelines for constructing a fluorescence microscope from scratch using standard optical components, offering flexibility in design and cost-effectiveness compared to commercial alternatives.
Article
Chemistry, Multidisciplinary
Ignacio Madrid, Zhiyong Zheng, Cedric Gerbelot, Akira Fujiwara, Shuo Li, Simon Grall, Katsuhiko Nishiguchi, Soo Hyeon Kim, Arnaud Chovin, Christophe Demaille, Nicolas Clement
Summary: The study investigated Brownian motion of tethered DNA under nanoconfinement, and found a transition into the ballistic Brownian motion regime for short DNA in sub-5 nm gaps.
Article
Chemistry, Multidisciplinary
Shuo Li, Yannick Coffinier, Chann Lagadec, Fabrizio Cleri, Katsuhiko Nishiguchi, Akira Fujiwara, Soo Hyeon Kim, Nicolas Clement
Summary: This study demonstrates the successful implementation of a single-cell electrochemical aptasensor array using nanopillar arrays combined with redox-labeled aptamers targeting EpCAM. This novel technology provides new opportunities for large-scale implementation and statistical analysis of early cancer diagnosis and therapy.
