标题
Precision oncology in the age of integrative genomics
作者
关键词
-
出版物
NATURE BIOTECHNOLOGY
Volume 36, Issue 1, Pages 46-60
出版商
Springer Nature
发表日期
2018-01-11
DOI
10.1038/nbt.4017
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Integrative clinical genomics of metastatic cancer
- (2017) Dan R. Robinson et al. NATURE
- Sharing Clinical and Genomic Data on Cancer — The Need for Global Solutions
- (2017) NEW ENGLAND JOURNAL OF MEDICINE
- Chromosomal chaos silences immune surveillance
- (2017) Maurizio Zanetti SCIENCE
- Tumor aneuploidy correlates with markers of immune evasion and with reduced response to immunotherapy
- (2017) Teresa Davoli et al. SCIENCE
- High-Throughput Genomics and Clinical Outcome in Hard-to-Treat Advanced Cancers: Results of the MOSCATO 01 Trial
- (2017) Christophe Massard et al. Cancer Discovery
- Liquid Biopsies for Cancer: Coming to a Patient near You
- (2017) Nithya Krishnamurthy et al. Journal of Clinical Medicine
- Gene Expression Analysis and Immunohistochemistry in Evaluation of Cancer of Unknown Primary: Time for a Patient-Centered Approach
- (2017) Charles R. Handorf Journal of the National Comprehensive Cancer Network
- Performance of ACMG-AMP Variant-Interpretation Guidelines among Nine Laboratories in the Clinical Sequencing Exploratory Research Consortium
- (2016) Laura M. Amendola et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Consideration of Cosegregation in the Pathogenicity Classification of Genomic Variants
- (2016) Gail P. Jarvik et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Clinical Sequencing Exploratory Research Consortium: Accelerating Evidence-Based Practice of Genomic Medicine
- (2016) Robert C. Green et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Epigenetic Therapeutics: A New Weapon in the War Against Cancer
- (2016) Nita Ahuja et al. Annual Review of Medicine
- The Emerging Hallmarks of Cancer Metabolism
- (2016) Natalya N. Pavlova et al. Cell Metabolism
- Microsatellite Instability as a Biomarker for PD-1 Blockade
- (2016) J. C. Dudley et al. CLINICAL CANCER RESEARCH
- Germline Analysis from Tumor–Germline Sequencing Dyads to Identify Clinically Actionable Secondary Findings
- (2016) Bryce A. Seifert et al. CLINICAL CANCER RESEARCH
- Systematic Evaluation of Sanger Validation of Next-Generation Sequencing Variants
- (2016) T. F. Beck et al. CLINICAL CHEMISTRY
- Incorporating genetic counseling into clinical care for children and adolescents with cancer
- (2016) Jessica N Everett et al. Future Oncology
- Massively parallel sequencing of phyllodes tumours of the breast reveals actionable mutations, andTERTpromoter hotspot mutations andTERTgene amplification as likely drivers of progression
- (2016) Salvatore Piscuoglio et al. JOURNAL OF PATHOLOGY
- Precision oncology: origins, optimism, and potential
- (2016) Vinay Prasad et al. LANCET ONCOLOGY
- Precision Oncology: The UC San Diego Moores Cancer Center PREDICT Experience
- (2016) M. Schwaederle et al. MOLECULAR CANCER THERAPEUTICS
- Perspective: The precision-oncology illusion
- (2016) Vinay Prasad NATURE
- T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer
- (2016) Eric Tran et al. NEW ENGLAND JOURNAL OF MEDICINE
- Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer
- (2016) Colin C. Pritchard et al. NEW ENGLAND JOURNAL OF MEDICINE
- Mutations Associated with Acquired Resistance to PD-1 Blockade in Melanoma
- (2016) Jesse M. Zaretsky et al. NEW ENGLAND JOURNAL OF MEDICINE
- The transformation of oncology
- (2016) H. Varmus SCIENCE
- Mutational signatures associated with tobacco smoking in human cancer
- (2016) L. B. Alexandrov et al. SCIENCE
- Mutational signatures of ionizing radiation in second malignancies
- (2016) Sam Behjati et al. Nature Communications
- Circulating tumor DNA detection in lung cancer patients before and after surgery
- (2016) Nannan Guo et al. Scientific Reports
- US president endorses “moonshot” effort to cure cancer
- (2016) Michael McCarthy BMJ-British Medical Journal
- Making sense of big data in health research: Towards an EU action plan
- (2016) Charles Auffray et al. Genome Medicine
- US president endorses “moonshot” effort to cure cancer
- (2016) Michael McCarthy BMJ-British Medical Journal
- Diagnostic Yield of Clinical Tumor and Germline Whole-Exome Sequencing for Children With Solid Tumors
- (2016) D. Williams Parsons et al. JAMA Oncology
- Association of AR-V7 on Circulating Tumor Cells as a Treatment-Specific Biomarker With Outcomes and Survival in Castration-Resistant Prostate Cancer
- (2016) Howard I. Scher et al. JAMA Oncology
- Complete Durable Response From Carboplatin and Olaparib in a Heavily Pretreated Triple-Negative Metastatic Breast Cancer With Germline BRCA2 and “BRCAness” Mutations
- (2016) Sanghee Hong et al. Journal of Oncology Practice
- Prospective phase II trial of trabectedin in BRCA-mutated and/or BRCAness phenotype recurrent ovarian cancer patients: the MITO 15 trial
- (2015) D. Lorusso et al. ANNALS OF ONCOLOGY
- SWI/SNF Chromatin Remodeling and Human Malignancies
- (2015) Julien Masliah-Planchon et al. Annual Review of Pathology-Mechanisms of Disease
- Long-term safety and anti-tumour activity of olaparib monotherapy after combination with carboplatin and paclitaxel in patients with advanced breast, ovarian or fallopian tube cancer
- (2015) Ruud van der Noll et al. BRITISH JOURNAL OF CANCER
- Anti-programmed cell death protein-1/ligand-1 therapy in different cancers
- (2015) B Homet Moreno et al. BRITISH JOURNAL OF CANCER
- Integrative Clinical Genomics of Advanced Prostate Cancer
- (2015) Dan Robinson et al. CELL
- Genomic Classification of Cutaneous Melanoma
- (2015) Rehan Akbani et al. CELL
- BRCAness Predicts Resistance to Taxane-Containing Regimens in Triple Negative Breast Cancer During Neoadjuvant Chemotherapy
- (2015) Sadako Akashi-Tanaka et al. Clinical Breast Cancer
- ALCHEMIST Trials: A Golden Opportunity to Transform Outcomes in Early-Stage Non-Small Cell Lung Cancer
- (2015) R. Govindan et al. CLINICAL CANCER RESEARCH
- Lung Master Protocol (Lung-MAP)--A Biomarker-Driven Protocol for Accelerating Development of Therapies for Squamous Cell Lung Cancer: SWOG S1400
- (2015) R. S. Herbst et al. CLINICAL CANCER RESEARCH
- Precision Medicine for Advanced Pancreas Cancer: The Individualized Molecular Pancreatic Cancer Therapy (IMPaCT) Trial
- (2015) L. A. Chantrill et al. CLINICAL CANCER RESEARCH
- Diagnostic Accuracy of Noninvasive Genotyping of EGFR in Lung Cancer Patients by Deep Sequencing of Plasma Cell-Free DNA
- (2015) J. Uchida et al. CLINICAL CHEMISTRY
- What have we learned from exceptional tumour responses?
- (2015) Niven Mehra et al. CURRENT OPINION IN ONCOLOGY
- Precision medicine at Memorial Sloan Kettering Cancer Center: clinical next-generation sequencing enabling next-generation targeted therapy trials
- (2015) David M. Hyman et al. DRUG DISCOVERY TODAY
- The use of exome capture RNA-seq for highly degraded RNA with application to clinical cancer sequencing
- (2015) Marcin Cieslik et al. GENOME RESEARCH
- Actionable exomic incidental findings in 6503 participants: challenges of variant classification
- (2015) Laura M. Amendola et al. GENOME RESEARCH
- Integrative Clinical Sequencing in the Management of Refractory or Relapsed Cancer in Youth
- (2015) Rajen J. Mody et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT)
- (2015) Donavan T. Cheng et al. JOURNAL OF MOLECULAR DIAGNOSTICS
- NCI-MATCH Launch Highlights New Trial Design in Precision-Medicine Era:
- (2015) Caroline McNeil JNCI-Journal of the National Cancer Institute
- Germline Findings in Tumor-Only Sequencing: Points to Consider for Clinicians and Laboratories: Table 1.
- (2015) Victoria M. Raymond et al. JNCI-Journal of the National Cancer Institute
- A Decision Support Framework for Genomically Informed Investigational Cancer Therapy
- (2015) Funda Meric-Bernstam et al. JNCI-Journal of the National Cancer Institute
- Molecularly targeted therapy based on tumour molecular profiling versus conventional therapy for advanced cancer (SHIVA): a multicentre, open-label, proof-of-concept, randomised, controlled phase 2 trial
- (2015) Christophe Le Tourneau et al. LANCET ONCOLOGY
- Pilot Trial of Selecting Molecularly Guided Therapy for Patients with Non-V600 BRAF-Mutant Metastatic Melanoma: Experience of the SU2C/MRA Melanoma Dream Team
- (2015) P. M. LoRusso et al. MOLECULAR CANCER THERAPEUTICS
- Non-invasive detection of genome-wide somatic copy number alterations by liquid biopsies
- (2015) Ellen Heitzer et al. Molecular Oncology
- Mutant MHC class II epitopes drive therapeutic immune responses to cancer
- (2015) Sebastian Kreiter et al. NATURE
- Alternative transcription initiation leads to expression of a novel ALK isoform in cancer
- (2015) Thomas Wiesner et al. NATURE
- Whole genomes redefine the mutational landscape of pancreatic cancer
- (2015) Nicola Waddell et al. NATURE
- A global reference for human genetic variation
- (2015) Richard A. Gibbs et al. NATURE
- NCI-MATCH pairs tumor mutations with matching drugs
- (2015) Vicki Brower NATURE BIOTECHNOLOGY
- Robust enumeration of cell subsets from tissue expression profiles
- (2015) Aaron M Newman et al. NATURE METHODS
- Exceptional responders—discovering predictive biomarkers
- (2015) Naoko Takebe et al. Nature Reviews Clinical Oncology
- NCI-MATCH trial pushes cancer umbrella trial paradigm
- (2015) Asher Mullard NATURE REVIEWS DRUG DISCOVERY
- PD-1 Blockade in Tumors with Mismatch-Repair Deficiency
- (2015) Dung T. Le et al. NEW ENGLAND JOURNAL OF MEDICINE
- Germline Mutations in Predisposition Genes in Pediatric Cancer
- (2015) Jinghui Zhang et al. NEW ENGLAND JOURNAL OF MEDICINE
- Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas
- (2015) NEW ENGLAND JOURNAL OF MEDICINE
- DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer
- (2015) Joaquin Mateo et al. NEW ENGLAND JOURNAL OF MEDICINE
- A New Initiative on Precision Medicine
- (2015) Francis S. Collins et al. NEW ENGLAND JOURNAL OF MEDICINE
- ClinVar: public archive of interpretations of clinically relevant variants
- (2015) Melissa J. Landrum et al. NUCLEIC ACIDS RESEARCH
- Somatic Copy Number Abnormalities and Mutations in PI3K/AKT/mTOR Pathway Have Prognostic Significance for Overall Survival in Platinum Treated Locally Advanced or Metastatic Urothelial Tumors
- (2015) Joaquim Bellmunt et al. PLoS One
- Neoantigens in cancer immunotherapy
- (2015) T. N. Schumacher et al. SCIENCE
- TERTpromoter mutations and telomerase reactivation in urothelial cancer
- (2015) Sumit Borah et al. SCIENCE
- Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer
- (2015) N. A. Rizvi et al. SCIENCE
- The future of immune checkpoint therapy
- (2015) P. Sharma et al. SCIENCE
- Precision cancer medicine: Hype or hope?
- (2015) Andrew Z. Wang Science Translational Medicine
- A mutational signature in gastric cancer suggests therapeutic strategies
- (2015) Ludmil B. Alexandrov et al. Nature Communications
- Patterns and functional implications of rare germline variants across 12 cancer types
- (2015) Charles Lu et al. Nature Communications
- Clinical Acquired Resistance to RAF Inhibitor Combinations in BRAF-Mutant Colorectal Cancer through MAPK Pathway Alterations
- (2015) L. G. Ahronian et al. Cancer Discovery
- ARID1A and TERT promoter mutations in dedifferentiated meningioma
- (2015) Malak S. Abedalthagafi et al. Cancer Genetics
- A multiplexed marker-based algorithm for diagnosis of carcinoma of unknown primary using circulating tumor cells
- (2015) Elizabeth M. Matthew et al. Oncotarget
- Landscape of gene fusions in epithelial cancers: seq and ye shall find
- (2015) Chandan Kumar-Sinha et al. Genome Medicine
- NCI-MATCH Launch Highlights New Trial Design in Precision-Medicine Era:
- (2015) Caroline McNeil JNCI-Journal of the National Cancer Institute
- Germline Findings in Tumor-Only Sequencing: Points to Consider for Clinicians and Laboratories: Table 1.
- (2015) Victoria M. Raymond et al. JNCI-Journal of the National Cancer Institute
- A Decision Support Framework for Genomically Informed Investigational Cancer Therapy
- (2015) Funda Meric-Bernstam et al. JNCI-Journal of the National Cancer Institute
- Genomic Correlate of Exceptional Erlotinib Response in Head and Neck Squamous Cell Carcinoma
- (2015) Eliezer M. Van Allen et al. JAMA Oncology
- Whole-Exome Sequencing of Metastatic Cancer and Biomarkers of Treatment Response
- (2015) Himisha Beltran et al. JAMA Oncology
- Detection of Somatic Copy Number Alterations in Cancer Using Targeted Exome Capture Sequencing
- (2015) Robert J. Lonigro et al. NEOPLASIA
- Modeling tissue contamination to improve molecular identification of the primary tumor site of metastases
- (2014) Martin Vincent et al. BIOINFORMATICS
- A Proteome-Scale Map of the Human Interactome Network
- (2014) Thomas Rolland et al. CELL
- Mutational signatures: the patterns of somatic mutations hidden in cancer genomes
- (2014) Ludmil B Alexandrov et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Social and behavioral research in genomic sequencing: approaches from the Clinical Sequencing Exploratory Research Consortium Outcomes and Measures Working Group
- (2014) Stacy W. Gray et al. GENETICS IN MEDICINE
- Most common ‘sporadic’ cancers have a significant germline genetic component
- (2014) Yi Lu et al. HUMAN MOLECULAR GENETICS
- Non–Small Cell Lung Cancer and Precision Medicine
- (2014) Boris Pasche et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Using Multiplexed Assays of Oncogenic Drivers in Lung Cancers to Select Targeted Drugs
- (2014) Mark G. Kris et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Clinical Significance of CTNNB1 Mutation and Wnt Pathway Activation in Endometrioid Endometrial Carcinoma
- (2014) Yuexin Liu et al. JNCI-Journal of the National Cancer Institute
- Olaparib maintenance therapy in patients with platinum-sensitive relapsed serous ovarian cancer: a preplanned retrospective analysis of outcomes by BRCA status in a randomised phase 2 trial
- (2014) Jonathan Ledermann et al. LANCET ONCOLOGY
- Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens
- (2014) Matthew M. Gubin et al. NATURE
- Integrated genomic characterization of adrenocortical carcinoma
- (2014) Guillaume Assié et al. NATURE GENETICS
- The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma
- (2014) Gang Wu et al. NATURE GENETICS
- Genome-wide analysis of noncoding regulatory mutations in cancer
- (2014) Nils Weinhold et al. NATURE GENETICS
- Systematic analysis of noncoding somatic mutations and gene expression alterations across 14 tumor types
- (2014) Nils J Fredriksson et al. NATURE GENETICS
- Rationale for co-targeting IGF-1R and ALK in ALK fusion–positive lung cancer
- (2014) Christine M Lovly et al. NATURE MEDICINE
- Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicine
- (2014) Eliezer M Van Allen et al. NATURE MEDICINE
- Implementing personalized cancer care
- (2014) Richard L. Schilsky Nature Reviews Clinical Oncology
- Mechanisms underlying mutational signatures in human cancers
- (2014) Thomas Helleday et al. NATURE REVIEWS GENETICS
- AR-V7 and Resistance to Enzalutamide and Abiraterone in Prostate Cancer
- (2014) Emmanuel S. Antonarakis et al. NEW ENGLAND JOURNAL OF MEDICINE
- OMIM.org: Online Mendelian Inheritance in Man (OMIM®), an online catalog of human genes and genetic disorders
- (2014) Joanna S. Amberger et al. NUCLEIC ACIDS RESEARCH
- Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma
- (2014) Jennifer A. Perry et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Transcriptome meta-analysis of lung cancer reveals recurrent aberrations in NRG1 and Hippo pathway genes
- (2014) Saravana M. Dhanasekaran et al. Nature Communications
- Synthetic Lethality in ATM-Deficient RAD50-Mutant Tumors Underlies Outlier Response to Cancer Therapy
- (2014) H. Al-Ahmadie et al. Cancer Discovery
- Activating mTOR Mutations in a Patient with an Extraordinary Response on a Phase I Trial of Everolimus and Pazopanib
- (2014) N. Wagle et al. Cancer Discovery
- APOBEC-Mediated Cytosine Deamination Links PIK3CA Helical Domain Mutations to Human Papillomavirus-Driven Tumor Development
- (2014) Stephen Henderson et al. Cell Reports
- RNA-Seq Accurately Identifies Cancer Biomarker Signatures to Distinguish Tissue of Origin
- (2014) Iris H. Wei et al. NEOPLASIA
- Personalized treatment of Sézary syndrome by targeting a novelCTLA4:CD28fusion
- (2014) Aleksandar Sekulic et al. Molecular Genetics & Genomic Medicine
- Promoting a new brain tumor mutation: TERT promoter mutations in CNS tumors
- (2013) Zachary J. Reitman et al. ACTA NEUROPATHOLOGICA
- ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing
- (2013) Robert C. Green et al. GENETICS IN MEDICINE
- Integrative and Comparative Genomic Analysis of Lung Squamous Cell Carcinomas in East Asian Patients
- (2013) Youngwook Kim et al. JOURNAL OF CLINICAL ONCOLOGY
- Comparative Effectiveness Research in Cancer Genomics and Precision Medicine: Current Landscape and Future Prospects
- (2013) N. I. Simonds et al. JNCI-Journal of the National Cancer Institute
- Landscape of DNA Virus Associations across Human Malignant Cancers: Analysis of 3,775 Cases Using RNA-Seq
- (2013) J. D. Khoury et al. JOURNAL OF VIROLOGY
- Integrated genomic characterization of endometrial carcinoma
- (2013) Gad Getz et al. NATURE
- Signatures of mutational processes in human cancer
- (2013) Ludmil B. Alexandrov et al. NATURE
- Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing
- (2013) Garrett M Frampton et al. NATURE BIOTECHNOLOGY
- APOBEC3B mutagenesis in cancer
- (2013) Kawai J Kuong et al. NATURE GENETICS
- Whole-genome and whole-exome sequencing of bladder cancer identifies frequent alterations in genes involved in sister chromatid cohesion and segregation
- (2013) Guangwu Guo et al. NATURE GENETICS
- Identification of recurrent NAB2-STAT6 gene fusions in solitary fibrous tumor by integrative sequencing
- (2013) Dan R Robinson et al. NATURE GENETICS
- From neural development to cognition: unexpected roles for chromatin
- (2013) Jehnna L. Ronan et al. NATURE REVIEWS GENETICS
- TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal
- (2013) P. J. Killela et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TERT Promoter Mutations in Familial and Sporadic Melanoma
- (2013) S. Horn et al. SCIENCE
- Highly Recurrent TERT Promoter Mutations in Human Melanoma
- (2013) F. W. Huang et al. SCIENCE
- Inhibition of PRC2 Activity by a Gain-of-Function H3 Mutation Found in Pediatric Glioblastoma
- (2013) P. W. Lewis et al. SCIENCE
- Frequency of TERT promoter mutations in human cancers
- (2013) João Vinagre et al. Nature Communications
- Identification of Targetable FGFR Gene Fusions in Diverse Cancers
- (2013) Yi-Mi Wu et al. Cancer Discovery
- K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas
- (2012) Dong-Anh Khuong-Quang et al. ACTA NEUROPATHOLOGICA
- Diagnostic work-up of carcinoma of unknown primary: from immunohistochemistry to molecular profiling
- (2012) K. A. Oien et al. ANNALS OF ONCOLOGY
- Exploiting the Mutanome for Tumor Vaccination
- (2012) J. C. Castle et al. CANCER RESEARCH
- Targeted Next-generation Sequencing of Advanced Prostate Cancer Identifies Potential Therapeutic Targets and Disease Heterogeneity
- (2012) Himisha Beltran et al. EUROPEAN UROLOGY
- Tumor Boards and the Quality of Cancer Care
- (2012) N. L. Keating et al. JNCI-Journal of the National Cancer Institute
- Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
- (2012) Jeremy Schwartzentruber et al. NATURE
- Assuring the quality of next-generation sequencing in clinical laboratory practice
- (2012) Amy S Gargis et al. NATURE BIOTECHNOLOGY
- Olaparib Maintenance Therapy in Platinum-Sensitive Relapsed Ovarian Cancer
- (2012) Jonathan Ledermann et al. NEW ENGLAND JOURNAL OF MEDICINE
- Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer
- (2012) Julie R. Brahmer et al. NEW ENGLAND JOURNAL OF MEDICINE
- Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer
- (2012) Suzanne L. Topalian et al. NEW ENGLAND JOURNAL OF MEDICINE
- Genome Sequencing Identifies a Basis for Everolimus Sensitivity
- (2012) G. Iyer et al. SCIENCE
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Durable Complete Responses in Heavily Pretreated Patients with Metastatic Melanoma Using T-Cell Transfer Immunotherapy
- (2011) S. A. Rosenberg et al. CLINICAL CANCER RESEARCH
- LOVD v.2.0: the next generation in gene variant databases
- (2011) Ivo F. A. C. Fokkema et al. HUMAN MUTATION
- Olaparib in patients with recurrent high-grade serous or poorly differentiated ovarian carcinoma or triple-negative breast cancer: a phase 2, multicentre, open-label, non-randomised study
- (2011) Karen A Gelmon et al. LANCET ONCOLOGY
- Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma
- (2011) Ignacio Varela et al. NATURE
- Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder
- (2011) Yaoting Gui et al. NATURE GENETICS
- Carcinomas of an unknown primary origin—diagnosis and treatment
- (2011) Christophe Massard et al. Nature Reviews Clinical Oncology
- Personalized Oncology Through Integrative High-Throughput Sequencing: A Pilot Study
- (2011) S. Roychowdhury et al. Science Translational Medicine
- High-Throughput Detection of Actionable Genomic Alterations in Clinical Tumor Samples by Targeted, Massively Parallel Sequencing
- (2011) Nikhil Wagle et al. Cancer Discovery
- Translating cancer research into targeted therapeutics
- (2010) J. S. de Bono et al. NATURE
- A map of human genome variation from population-scale sequencing
- (2010) Richard M. Durbin et al. NATURE
- Genomic Analysis Using High-Density Single Nucleotide Polymorphism-Based Oligonucleotide Arrays and Multiplex Ligation-Dependent Probe Amplification Provides a Comprehensive Analysis of INI1/SMARCB1 in Malignant Rhabdoid Tumors
- (2009) E. M. Jackson et al. CLINICAL CANCER RESEARCH
- Evaluating the utility of personal genomic information
- (2009) Morris W Foster et al. GENETICS IN MEDICINE
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