PEGylation of therapeutic oligonucletides: From linear to highly branched PEG architectures
出版年份 2018 全文链接
标题
PEGylation of therapeutic oligonucletides: From linear to highly branched PEG architectures
作者
关键词
PEGylation, oligonucleotide, brush polymer, antisense, small interfering RNA, aptamer, phosphorothioate
出版物
Nano Research
Volume -, Issue -, Pages -
出版商
Springer Nature
发表日期
2018-07-06
DOI
10.1007/s12274-018-2131-8
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Depth-Profiling the Nuclease Stability and the Gene Silencing Efficacy of Brush-Architectured Poly(ethylene glycol)–DNA Conjugates
- (2017) Fei Jia et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- FDA-Approved Oligonucleotide Therapies in 2017
- (2017) Cy A. Stein et al. MOLECULAR THERAPY
- The chemical evolution of oligonucleotide therapies of clinical utility
- (2017) Anastasia Khvorova et al. NATURE BIOTECHNOLOGY
- Nusinersen, an antisense oligonucleotide drug for spinal muscular atrophy
- (2017) David R Corey NATURE NEUROSCIENCE
- Characterizing the effect of GalNAc and phosphorothioate backbone on binding of antisense oligonucleotides to the asialoglycoprotein receptor
- (2017) Karsten Schmidt et al. NUCLEIC ACIDS RESEARCH
- Modulating the Cellular Immune Response of Oligonucleotides by Brush Polymer-Assisted Compaction
- (2017) Xueyan Cao et al. Small
- FDA Approves Eteplirsen for Duchenne Muscular Dystrophy: The Next Chapter in the Eteplirsen Saga
- (2017) Annemieke Aartsma-Rus et al. Nucleic Acid Therapeutics
- A Novel PEGylation Method for Improving the Pharmacokinetic Properties of Anti-Interleukin-17A RNA Aptamers
- (2017) Kazuhiko Haruta et al. Nucleic Acid Therapeutics
- Preclinical and Clinical Advances of GalNAc-Decorated Nucleic Acid Therapeutics
- (2017) Yuanyu Huang Molecular Therapy-Nucleic Acids
- Therapeutic nucleic acids: current clinical status
- (2016) Kannan Sridharan et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release
- (2016) Nazila Kamaly et al. CHEMICAL REVIEWS
- Lipid nanoparticles for targeted siRNA delivery – going from bench to bedside
- (2016) Victor Kotelianski et al. International Journal of Nanomedicine
- Pre-existing anti-PEG antibodies are associated with severe immediate allergic reactions to pegnivacogin, a PEGylated aptamer
- (2016) Thomas J. Povsic et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Effective Antisense Gene Regulation via Noncationic, Polyethylene Glycol Brushes
- (2016) Xueguang Lu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Protein adsorption is required for stealth effect of poly(ethylene glycol)- and poly(phosphoester)-coated nanocarriers
- (2016) Susanne Schöttler et al. Nature Nanotechnology
- Organic Solvent Nanofiltration (OSN): A New Technology Platform for Liquid-Phase Oligonucleotide Synthesis (LPOS)
- (2016) Jeong F. Kim et al. ORGANIC PROCESS RESEARCH & DEVELOPMENT
- Pharmacokinetics, biodistribution and cell uptake of antisense oligonucleotides
- (2015) Richard S. Geary et al. ADVANCED DRUG DELIVERY REVIEWS
- Mipomersen, an Antisense Oligonucleotide to Apolipoprotein B-100, Reduces Lipoprotein(a) in Various Populations With HypercholesterolemiaSignificance
- (2015) Raul D. Santos et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Mipomersen and lomitapide: Two new drugs for the treatment of homozygous familial hypercholesterolemia
- (2015) Ioanna Gouni-Berthold et al. ATHEROSCLEROSIS SUPPLEMENTS
- Facile synthesis of nucleic acid–polymer amphiphiles and their self-assembly
- (2015) Fei Jia et al. CHEMICAL COMMUNICATIONS
- Nucleic Acid Therapeutics Using Polyplexes: A Journey of 50 Years (and Beyond)
- (2015) Ulrich Lächelt et al. CHEMICAL REVIEWS
- Liquid-Phase Synthesis of 2′-Methyl-RNA on a Homostar Support through Organic-Solvent Nanofiltration
- (2015) Piers R. J. Gaffney et al. CHEMISTRY-A EUROPEAN JOURNAL
- Clinical and Preclinical Pharmacokinetics and Pharmacodynamics of Mipomersen (Kynamro®): A Second-Generation Antisense Oligonucleotide Inhibitor of Apolipoprotein B
- (2015) Richard S. Geary et al. CLINICAL PHARMACOKINETICS
- miR-122 is a Unique Molecule with Great Potential in Diagnosis, Prognosis of Liver Disease, and Therapy Both as miRNA Mimic and Antimir
- (2015) Sharda Thakral et al. CURRENT GENE THERAPY
- Turning mirror-image oligonucleotides into drugs: the evolution of Spiegelmer® therapeutics
- (2015) Axel Vater et al. DRUG DISCOVERY TODAY
- Providing Oligonucleotides with Steric Selectivity by Brush-Polymer-Assisted Compaction
- (2015) Xueguang Lu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Efficacy and safety of patisiran for familial amyloidotic polyneuropathy: a phase II multi-dose study
- (2015) Ole B Suhr et al. Orphanet Journal of Rare Diseases
- Delivery systems for siRNA drug development in cancer therapy
- (2015) Cong-fei Xu et al. Asian Journal of Pharmaceutical Sciences
- miR-34: from bench to bedside
- (2015) Massimiliano Agostini et al. Oncotarget
- Enzymatic Formation of PEGylated Oligonucleotides
- (2014) Alice Sosic et al. BIOCONJUGATE CHEMISTRY
- Oligonucleotides conjugated with short chemically defined polyethylene glycol chains are efficient antisense agents
- (2014) Nasrin Shokrzadeh et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Impacts of PEGylation on the gene and oligonucleotide delivery system
- (2014) Yutaka Ikeda et al. JOURNAL OF APPLIED POLYMER SCIENCE
- Splice-correcting oligonucleotides restore BTK function in X-linked agammaglobulinemia model
- (2014) Burcu Bestas et al. JOURNAL OF CLINICAL INVESTIGATION
- Non-viral vectors for gene-based therapy
- (2014) Hao Yin et al. NATURE REVIEWS GENETICS
- Degradable lipid nanoparticles with predictable in vivo siRNA delivery activity
- (2014) Kathryn A. Whitehead et al. Nature Communications
- Nucleic acid therapeutics: basic concepts and recent developments
- (2014) Vivek K. Sharma et al. RSC Advances
- The Spiegelmer NOX-A12, a novel CXCL12 inhibitor, interferes with chronic lymphocytic leukemia cell motility and causes chemosensitization
- (2013) J. Hoellenriegel et al. BLOOD
- Effects of Molecular Crowding on the Structures, Interactions, and Functions of Nucleic Acids
- (2013) Shu-ichi Nakano et al. CHEMICAL REVIEWS
- Gene regulation by antisense transcription
- (2013) Vicent Pelechano et al. NATURE REVIEWS GENETICS
- Designing Chemically Modified Oligonucleotides for Targeted Gene Silencing
- (2012) Glen F. Deleavey et al. CHEMISTRY & BIOLOGY
- Antibodies against polyethylene glycol in healthy subjects and in patients treated with PEG-conjugated agents
- (2012) Ricardo P Garay et al. Expert Opinion on Drug Delivery
- PEGylated PRINT Nanoparticles: The Impact of PEG Density on Protein Binding, Macrophage Association, Biodistribution, and Pharmacokinetics
- (2012) Jillian L. Perry et al. NANO LETTERS
- RNA therapeutics: beyond RNA interference and antisense oligonucleotides
- (2012) Ryszard Kole et al. NATURE REVIEWS DRUG DISCOVERY
- Current drug research on PEGylation with small molecular agents
- (2012) Wenjun Li et al. PROGRESS IN POLYMER SCIENCE
- Stabilization and Photochemical Regulation of Antisense Agents through PEGylation
- (2011) Jeane M. Govan et al. BIOCONJUGATE CHEMISTRY
- Effects of PEG size on structure, function and stability of PEGylated BSA
- (2011) Bitten Plesner et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- CpG DNA as a vaccine adjuvant
- (2011) Christian Bode et al. Expert Review of Vaccines
- Polymer Brushes by the “Grafting to” Method
- (2011) Bogdan Zdyrko et al. MACROMOLECULAR RAPID COMMUNICATIONS
- Circulating microRNA in body fluid: a new potential biomarker for cancer diagnosis and prognosis
- (2010) Nobuyoshi Kosaka et al. CANCER SCIENCE
- MicroRNA-21: From Cancer to Cardiovascular Disease
- (2010) Virginija Jazbutyte et al. CURRENT DRUG TARGETS
- Stealth nanoparticles: High density but sheddable PEG is a key for tumor targeting
- (2010) Shyh-Dar Li et al. JOURNAL OF CONTROLLED RELEASE
- Gene silencing efficiency of siRNA-PEG conjugates: Effect of PEGylation site and PEG molecular weight
- (2010) Sooyeon Jung et al. JOURNAL OF CONTROLLED RELEASE
- Core-Clickable PEG-Branch-Azide Bivalent-Bottle-Brush Polymers by ROMP: Grafting-Through and Clicking-To
- (2010) Jeremiah A. Johnson et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Functional nanoparticles for molecular imaging guided gene delivery
- (2010) Gang Liu et al. Nano Today
- Aptamers Generated from Cell-SELEX for Molecular Medicine: A Chemical Biology Approach
- (2009) Xiaohong Fang et al. ACCOUNTS OF CHEMICAL RESEARCH
- Ultralow-Fouling, Functionalizable, and Hydrolyzable Zwitterionic Materials and Their Derivatives for Biological Applications
- (2009) Shaoyi Jiang et al. ADVANCED MATERIALS
- Antisense oligonucleotide pharmacokinetics and metabolism
- (2009) Richard S Geary Expert Opinion on Drug Metabolism & Toxicology
- PEG Branched Polymer for Functionalization of Nanomaterials with Ultralong Blood Circulation
- (2009) Giuseppe Prencipe et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Sequencing technologies — the next generation
- (2009) Michael L. Metzker NATURE REVIEWS GENETICS
- Molecular crowding effects on structure and stability of DNA
- (2008) Daisuke Miyoshi et al. BIOCHIMIE
- Zwitterionic Polymers Exhibiting High Resistance to Nonspecific Protein Adsorption from Human Serum and Plasma
- (2008) Jon Ladd et al. BIOMACROMOLECULES
- Cationic shell-crosslinked knedel-like nanoparticles for highly efficient gene and oligonucleotide transfection of mammalian cells
- (2008) Ke Zhang et al. BIOMATERIALS
- A combinatorial library of lipid-like materials for delivery of RNAi therapeutics
- (2008) Akin Akinc et al. NATURE BIOTECHNOLOGY
- Synthesis and enzymatic stability of PEGylated oligonucleotide duplexes and their self-assemblies with polyamidoamine dendrimers
- (2007) Mahmoud Elsabahy et al. Soft Matter
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