Shank3 mutation in a mouse model of autism leads to changes in the S-nitroso-proteome and affects key proteins involved in vesicle release and synaptic function

Automated Online Solid-Phase Derivatization for Sensitive Quantification of Endogenous S-Nitrosoglutathione and Rapid Capture of Other Low-Molecular-Mass S-Nitrosothiols

(2018) Xin Wang et al.   ANALYTICAL CHEMISTRY

A Multiplex Enzymatic Machinery for Cellular Protein S-nitrosylation

(2018) Divya Seth et al.   MOLECULAR CELL

SHANK proteins: roles at the synapse and in autism spectrum disorder

(2017) Patricia Monteiro et al.   NATURE REVIEWS NEUROSCIENCE

Environmental risk factors for autism: an evidence-based review of systematic reviews and meta-analyses

(2017) Amirhossein Modabbernia et al.   Molecular Autism

Proteomic Analysis of Post-synaptic Density Fractions from Shank3 Mutant Mice Reveals Brain Region Specific Changes Relevant to Autism Spectrum Disorder

(2017) Dominik Reim et al.   Frontiers in Molecular Neuroscience

Dynamic Akt/mTOR Signaling in Children with Autism Spectrum Disorder

(2017) Charity Onore et al.   Frontiers in Pediatrics

System-based proteomic and metabonomic analysis of the Df(16)A +/− mouse identifies potential miR-185 targets and molecular pathway alterations

(2016) H Wesseling et al.   MOLECULAR PSYCHIATRY

Adult restoration of Shank3 expression rescues selective autistic-like phenotypes

(2016) Yuan Mei et al.   NATURE

Neurobiology of social behavior abnormalities in autism and Williams syndrome

(2016) Boaz Barak et al.   NATURE NEUROSCIENCE

Early hyperactivity and precocious maturation of corticostriatal circuits in Shank3B−/− mice

(2016) Rui T Peixoto et al.   NATURE NEUROSCIENCE

Mice with Shank3 Mutations Associated with ASD and Schizophrenia Display Both Shared and Distinct Defects

(2016) Yang Zhou et al.   NEURON

KEGG: new perspectives on genomes, pathways, diseases and drugs

(2016) Minoru Kanehisa et al.   NUCLEIC ACIDS RESEARCH

S-nitrosation of proteins relevant to Alzheimer’s disease during early stages of neurodegeneration

(2016) Uthpala Seneviratne et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CLK2 inhibition ameliorates autistic features associated with SHANK3 deficiency

(2016) Michael Bidinosti et al.   SCIENCE

Pathway Network Analyses for Autism Reveal Multisystem Involvement, Major Overlaps with Other Diseases and Convergence upon MAPK and Calcium Signaling

(2016) Ya Wen et al.   PLoS One

The role of the nitric oxide pathway in brain injury and its treatment — From bench to bedside

(2015) P.S. Garry et al.   EXPERIMENTAL NEUROLOGY

From the genetic architecture to synaptic plasticity in autism spectrum disorder

(2015) Thomas Bourgeron   NATURE REVIEWS NEUROSCIENCE

Aberrant protein S-nitrosylation contributes to the pathophysiology of neurodegenerative diseases

(2015) Tomohiro Nakamura et al.   NEUROBIOLOGY OF DISEASE

Regulation of brain glutamate metabolism by nitric oxide and S-nitrosylation

(2015) Karthik Raju et al.   Science Signaling

Regulation of brain glutamate metabolism by nitric oxide and S-nitrosylation

(2015) Karthik Raju et al.   Science Signaling

Target-Selective Protein S-Nitrosylation by Sequence Motif Recognition

(2014) Jie Jia et al.   CELL

The role of de novo mutations in the genetics of autism spectrum disorders

(2014) Michael Ronemus et al.   NATURE REVIEWS GENETICS

STRING v10: protein–protein interaction networks, integrated over the tree of life

(2014) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Proteomic analysis of post mortem brain tissue from autism patients: evidence for opposite changes in prefrontal cortex and cerebellum in synaptic connectivity-related proteins

(2014) Jantine AC Broek et al.   Molecular Autism

Reduction of cardiomyocyte S-nitrosylation by S-nitrosoglutathione reductase protects against sepsis-induced myocardial depression

(2013) Patrick Y. Sips et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

S-Nitrosylation of Dynamin-Related Protein 1 Mediates Mutant Huntingtin-Induced Mitochondrial Fragmentation and Neuronal Injury in Huntington's Disease

(2013) Florian Haun et al.   ANTIOXIDANTS & REDOX SIGNALING

Hepatocarcinogenesis Driven by GSNOR Deficiency Is Prevented by iNOS Inhibition

(2013) C.-H. Tang et al.   CANCER RESEARCH

Mechanism-Based Triarylphosphine-Ester Probes for Capture of Endogenous RSNOs

(2013) Uthpala Seneviratne et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Corticostriatal connectivity and its role in disease

(2013) Gordon M. G. Shepherd   NATURE REVIEWS NEUROSCIENCE

Aberrant Protein S-Nitrosylation in Neurodegenerative Diseases

(2013) Tomohiro Nakamura et al.   NEURON

S-nitrosylated SHP-2 contributes to NMDA receptor-mediated excitotoxicity in acute ischemic stroke

(2013) Z.-Q. Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GluR6-FasL-Trx2 mediates denitrosylation and activation of procaspase-3 in cerebral ischemia/reperfusion in rats

(2013) N Sun et al.   Cell Death & Disease

Functional Consequences of Mutations in Postsynaptic Scaffolding Proteins and Relevance to Psychiatric Disorders

(2012) Jonathan T. Ting et al.   Annual Review of Neuroscience

Mechanisms of S-nitrosothiol formation and selectivity in nitric oxide signaling

(2012) Brian C Smith et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Cellular and synaptic network defects in autism

(2012) João Peça et al.   CURRENT OPINION IN NEUROBIOLOGY

Prevalence of SHANK3 variants in patients with different subtypes of autism spectrum disorders

(2012) Luigi Boccuto et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Enzymatic mechanisms regulating protein S-nitrosylation: implications in health and disease

(2012) Puneet Anand et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Autism-Associated Mutations in ProSAP2/Shank3 Impair Synaptic Transmission and Neurexin-Neuroligin-Mediated Transsynaptic Signaling

(2012) M. H. Arons et al.   JOURNAL OF NEUROSCIENCE

Neural functions of calcineurin in synaptic plasticity and memory

(2012) K. Baumgartel et al.   LEARNING & MEMORY

Genetic Heritability and Shared Environmental Factors Among Twin Pairs With Autism

(2011) Joachim Hallmayer   ARCHIVES OF GENERAL PSYCHIATRY

Neurobiology of obsessive–compulsive disorder: insights into neural circuitry dysfunction through mouse genetics

(2011) Jonathan T Ting et al.   CURRENT OPINION IN NEUROBIOLOGY

Shank3 mutant mice display autistic-like behaviours and striatal dysfunction

(2011) João Peça et al.   NATURE

Rare De Novo Variants Associated with Autism Implicate a Large Functional Network of Genes Involved in Formation and Function of Synapses

(2011) Sarah R. Gilman et al.   NEURON

Site-specific and redox-controlled S-nitrosation of thioredoxin

(2011) K. T. Barglow et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

S-Nitrosylation activates Cdk5 and contributes to synaptic spine loss induced by  -amyloid peptide

(2011) J. Qu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Postsynaptic Organization of Synapses

(2011) M. Sheng et al.   Cold Spring Harbor Perspectives in Biology

Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication

(2011) Ozlem Bozdagi et al.   Molecular Autism

Metabotropic Glutamate Receptors: Physiology, Pharmacology, and Disease

(2010) Colleen M. Niswender et al.   Annual Review of Pharmacology and Toxicology

A synaptic trek to autism

(2009) Thomas Bourgeron   CURRENT OPINION IN NEUROBIOLOGY

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Protein denitrosylation: enzymatic mechanisms and cellular functions

(2009) Moran Benhar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Novel de novo SHANK3 mutation in autistic patients

(2008) Julie Gauthier et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Habits, Rituals, and the Evaluative Brain

(2008) Ann M. Graybiel   Annual Review of Neuroscience

S-nitrosylation of syntaxin 1 at Cys145is a regulatory switch controlling Munc18-1 binding

(2008) Zoë J. Palmer et al.   BIOCHEMICAL JOURNAL