Article
Biochemistry & Molecular Biology
Zongju Yang, Baiqiang Yan, Huixue Dong, Guanhua He, Yun Zhou, Jiaqiang Sun
Summary: The study identified a new BZR1-interacting protein, BIC1, which positively regulates BR signaling and acts as a transcriptional coactivator. BIC1 cooperates with PIF4 to activate downstream gene expression, and interacts with BZR1 to regulate common target genes. These findings provide mechanistic insights into BR signaling integration in plants.
Article
Biochemistry & Molecular Biology
Tongtong Liu, Suren Deng, Cheng Zhang, Xu Yang, Lei Shi, Fangsen Xu, Sheliang Wang, Chuang Wang
Summary: Plants have evolved a local Pi signaling pathway to solubilize occluded Fe-P or Al-P oxides by inducing malate secretion. Pi limitation impairs brassinosteroid signaling and downregulates BZR1 expression in Arabidopsis. Exogenous treatment with 2,4-epibrassinolide or constitutive activation of BZR1 significantly reduces primary root growth inhibition under Pi-starvation conditions by downregulating ALMT1 expression and malate secretion.
JOURNAL OF INTEGRATIVE PLANT BIOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Shengmin An, Yue Liu, Kangqi Sang, Ting Wang, Jingquan Yu, Yanhong Zhou, Xiaojian Xia
Summary: The BR signaling pathway enhances chilling tolerance in tomato by promoting ABA biosynthesis.
JOURNAL OF INTEGRATIVE PLANT BIOLOGY
(2023)
Article
Plant Sciences
Gabriel Gomez-Ocampo, Carlos D. Crocco, Jimena Cascales, Jana Oklestkova, Danuse Tarkowska, Miroslav Strnad, Santiago Mora-Garcia, Jose L. Pruneda-Paz, Miguel A. Blazquez, Javier F. Botto
Summary: B-Box-containing zinc finger transcription factor BBX21 inhibits hypocotyl elongation in Arabidopsis through the brassinosteroid pathway. It reduces sensitivity to synthetic active brassinosteroid 24-epiBL at low concentrations in simulated shade and represses the biosynthesis and signaling genes of brassinosteroids. BBX21 integrates brassinosteroid homeostasis and shade-light signaling to fine-tune hypocotyl elongation in Arabidopsis.
PLANT AND CELL PHYSIOLOGY
(2023)
Article
Multidisciplinary Sciences
Natalie M. Clark, Trevor M. Nolan, Ping Wang, Gaoyuan Song, Christian Montes, Conner T. Valentine, Hongqing Guo, Rosangela Sozzani, Yanhai Yin, Justin W. Walley
Summary: This study analyzed the BR signaling in Arabidopsis by integrating multiple omics datasets and inferring networks, identifying a BR-regulated transcription factor BRONTOSAURUS that affects cell division in roots. The research provides insights into the molecular signaling events during BR response through integrative network analysis applied to multi-omic data.
NATURE COMMUNICATIONS
(2021)
Article
Biochemistry & Molecular Biology
Huachun Sheng, Shuangxi Zhang, Yanping Wei, Shaolin Chen
Summary: The research showed that low concentrations of sugars could enhance plant growth in the dark conditions, depending on BR hormone biosynthesis and TOR activation.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Agronomy
Xiaofang Xie, Yanhua Jiang, Wenqi Xu, Weiguang Yang, Weixia Lei, Duo Qian, Jie Gao, Fangfang Cai, Dongliang Yu, Liping Ke, Zhixiong Fan
Summary: We demonstrate a short-cycle Brassica napus line, Sef1, with an efficient and fast transformation system, which has great potential for large-scale functional gene analysis.
THEORETICAL AND APPLIED GENETICS
(2023)
Article
Plant Sciences
Guohua Chai, Guang Qi, Dian Wang, Yamei Zhuang, Hua Xu, Zetao Bai, Ming-Yi Bai, Ruibo Hu, Zeng-Yu Wang, Gongke Zhou, Yingzhen Kong
Summary: This study reveals the negative regulatory mechanism of the Arabidopsis CCCH protein C3H15 in cell elongation through inhibiting brassinosteroid signaling. C3H15 functions downstream of the BRI1 receptor as a negative regulator in the BR pathway. It is phosphorylated by the kinase BIN2 and its dephosphorylation leads to its accumulation in the nucleus, where it regulates transcription of G-rich elements. C3H15 and the transcriptional regulators BZR1 and BES1 antagonize each other and share common BR-responsive target genes.
Article
Plant Sciences
Jingjie Zhang, Weiyue Chen, Xiaopeng Li, Hongyong Shi, Minghui Lv, Liming He, Wenhua Bai, Shujing Cheng, Jinfang Chu, Kai He, Xiaoping Gou, Jia Li
Summary: An apical hook is a crucial structure in dicotyledonous plants that protects the shoot apical meristem during seed germination and hypocotyl elongation. Previous studies have shown that the phytohormones BR and JA regulate apical hook formation antagonistically. This study reveals that JAs repress BRs by inhibiting the transcriptional activation of BZR1 by MYC2, disrupting the interaction between BZR1 and its partner transcription factors, and downregulating the expression of target genes important for apical hook development.
Article
Biotechnology & Applied Microbiology
Chunliu Zuo, Lan Zhang, Xinyue Yan, Xinyue Guo, Qing Zhang, Songyang Li, Yanling Li, Wen Xu, Xiaoming Song, Jinpeng Wang, Min Yuan
Summary: This study identified nine BZR1 genes in celery and demonstrated their important roles in plant development. The findings provide a foundation for further research on agronomic traits and environmental adaptation of celery.
Article
Biochemistry & Molecular Biology
Wenbin Zhang, Yang Tang, Yilong Hu, Yuhua Yang, Jiajia Cai, Hailun Liu, Chunyu Zhang, Xu Liu, Xingliang Hou
Summary: NF-YC proteins act as essential repressors of the BR pathway during light-controlled hypocotyl growth in Arabidopsis, inhibiting BR biosynthesis and signaling to ensure photomorphogenic growth.
Article
Plant Sciences
Zhiyong Li, Yajuan Fu, Yuzhu Wang, Jiansheng Liang
Summary: This study reveals that the scaffold protein RACK1 is involved in the BR signaling pathway in Arabidopsis by mediating the nuclear localization of BZR1. RACK1 interacts with BZR1 and competes with 14-3-3 proteins, leading to enhanced nuclear localization of BZR1. Furthermore, BR treatment disrupts the interaction between 14-3-3 and RACK1/BZR1, promoting the nuclear localization of BZR1.
Article
Biochemistry & Molecular Biology
Pingping Fang, Yu Wang, Mengqi Wang, Feng Wang, Cheng Chi, Yanhong Zhou, Jie Zhou, Kai Shi, Xiaojian Xia, Christine Helen Foyer, Jingquan Yu
Summary: This study reveals that the crosstalk between BZR1 and reactive oxygen species mediates cold- and BR-activated CBF expression, leading to enhanced cold tolerance in tomato.
Article
Biochemistry & Molecular Biology
Jing Cao, Yuxia Liang, Tingting Yan, Xuncheng Wang, Hua Zhou, Chen Chen, Yingli Zhang, Beihong Zhang, Shuhao Zhang, Juncheng Liao, Shujing Cheng, Jinfang Chu, Xi Huang, Dongqing Xu, Jia Li, Xing Wang Deng, Fang Lin
Summary: The photomorphogenic repressors BBX28 and BBX29 integrate light and brassinosteroid signaling by promoting BR-ENHANCED EXPRESSION transcriptional activity to precisely regulate seedling development. BBX28 and BBX29 physically interact with BEE1, BEE2, and BEE3 to enhance their binding to and activation of target genes, thus participating in the coordination of light and BR signaling.
Article
Biochemistry & Molecular Biology
Zhi-Liang Yue, Ning Liu, Zhi-Ping Deng, Yu Zhang, Zhi-Ming Wu, Ji-Long Zhao, Ying Sun, Zhi-Yong Wang, Sheng-Wei Zhang
Summary: This study reveals the important role of the OsWAK11 gene in rice, which regulates agronomical traits and BR signaling by controlling cell elongation rates. OsWAK11 directly interacts with the BR receptor OsBRI1 and inhibits BR signaling. Additionally, OsWAK11 shows a stronger affinity for methyl-esterified pectin and is regulated by changes in pectin methylesterification in response to light.
Article
Biochemistry & Molecular Biology
Zicong Li, Xiao Luo, Yang Ou, Huijun Jiao, Li Peng, Xing Fu, Alberto P. Macho, Renyi Liu, Yuehui He
Summary: JAZ proteins interact with Polycomb proteins to repress JA-responsive genes in plants. Reduction of Polycomb protein-mediated chromatin silencing partially rescues developmental defects caused by JA signaling.
Article
Multidisciplinary Sciences
Hongmiao Hu, Shu Tian, Guohui Xie, Rui Liu, Nana Wang, Sisi Li, Yuehui He, Jiamu Du
Summary: TEM1 combinatorically recognizes the FT gene 5'-UTR by binding to both the AP2 and B3 domains, recruiting the PRC2 to deposit H3K27me3 at the FT 5'-UTR, thereby precisely regulating the floral transition.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Review
Biochemistry & Molecular Biology
Xiao Luo, Mengnan Yin, Yuehui He
Summary: This article summarizes the recent progress in understanding the molecular mechanisms underlying the photoperiod control of flowering in the long-day plant Arabidopsis and the short-day plant soybean, and discusses the conservation and diversification of photoperiodic regulation of flowering in these two species.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Biochemistry & Molecular Biology
Hakim Manghwar, Jianming Li
Summary: Plants are sensitive to various stresses that can lead to diseases, but they have defense mechanisms to cope with these stresses. The endoplasmic reticulum (ER) plays a crucial role in protein folding, but this process can be disrupted by stresses, causing ER stress. We discuss ER stress, the unfolded protein response (UPR) and strategies for reducing ER stress in plants.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Xiaolin Zeng, Xinchen Lv, Rui Liu, Hang He, Shiqi Liang, Lixian Chen, Fan Zhang, Liu Chen, Yuehui He, Jiamu Du
Summary: The transcription factor CONSTANS (CO) forms a head-to-tail oligomeric configuration via its B-boxes to mediate the activation of florigen FLOWERING LOCUS T (FT) in long days. The multimerization of CO is crucial for its functionality.
JOURNAL OF INTEGRATIVE PLANT BIOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Guokai Xu, Zeng Tao, Yuehui He
Summary: This study reveals the molecular mechanisms underlying the reactivation of the FLC gene during plant embryonic development, ensuring that each generation must experience winter cold before flowering.
Review
Biochemistry & Molecular Biology
Weimeng Song, Li Hu, Zhihui Ma, Lei Yang, Jianming Li
Summary: Protein phosphorylation is a common post-translational modification that regulates various biological processes. Recent studies have shown that tyrosine phosphorylation, which was believed to be less common in plants compared to animals, plays important regulatory roles in plant growth, development, and interactions with the environment.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Biochemistry & Molecular Biology
Zhaoxu Gao, Yue Zhou, Yuehui He
Summary: This article summarizes the chromatin-based mechanisms of acquired thermotolerance and memory in plants, focusing on the adaptation and memory abilities of plants towards temperature stresses and winter cold. It also discusses the future research directions for temperature stress memory in economically-important crops.
JOURNAL OF GENETICS AND GENOMICS
(2022)
Article
Multidisciplinary Sciences
Yuqiu Wang, Yangyang Fan, De Fan, Yubo Zhang, Xiaoli Zhou, Ruikai Zhang, Yao Wang, Yujie Sun, Wei Zhang, Yuehui He, Xing Wang Deng, Danmeng Zhu
Summary: In this study, a plant-specific component of the DREAM complex called BTE1 was identified. It was found that the DREAM complex containing BTE1 acts against the COMPASS-like complex to repress transcription and occupancy of H3K4me3 at target genes. BTE1 was shown to interact with WDR5A, inhibiting its chromatin binding and transcription elongation on DREAM target genes.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Biology
Myeongjune Jeon, Goowon Jeong, Yupeng Yang, Xiao Luo, Daesong Jeong, Jinseul Kyung, Youbong Hyun, Yuehui He, Ilha Lee
Summary: To synchronize flowering time with spring, plants undergo vernalization, a process triggered by exposure to long-term winter cold. In Arabidopsis thaliana, this is achieved through cold-mediated epigenetic silencing of the floral repressor, FLOWERING LOCUS C (FLC). COOLAIR, a cold-induced antisense RNA, facilitates FLC silencing.
Article
Plant Sciences
Hua Cheng, Jiaxin Zhang, Yu Zhang, Chaona Si, Juanjuan Wang, Zheng Gao, Peipei Cao, Peilei Cheng, Yuehui He, Sumei Chen, Fadi Chen, Jiafu Jiang
Summary: This study revealed a synergistic relationship between the CCT protein CmNRRa and the 14-3-3 protein Cm14-3-3 mu in flowering repression in chrysanthemum.
JOURNAL OF EXPERIMENTAL BOTANY
(2023)
Article
Biochemistry & Molecular Biology
Zheng Gao, Yaxiao Li, Yang Ou, Mengnan Yin, Tao Chen, Xiaolin Zeng, Renjie Li, Yuehui He
Letter
Multidisciplinary Sciences
Zhicheng Zhang, Xiao Luo, Yupeng Yang, Yuehui He
Article
Multidisciplinary Sciences
Fei Huang, Xiao Luo, Yang Ou, Zhaoxu Gao, Qiming Tang, Zhenzhen Chu, Xinguang Zhu, Yuehui He
Summary: The tricarboxylic acid cycle-associated enzyme alpha-ketoglutarate dehydrogenase (KGDH) regulates alpha-ketoglutarate-dependent histone demethylation by interacting with JMJ, thereby controlling genome-wide gene expression in plants.
Article
Biochemistry & Molecular Biology
Xinchen Lv, Xiaolin Zeng, Hongmiao Hu, Lixian Chen, Fan Zhang, Rui Liu, Yue Liu, Xuelin Zhou, Changshi Wang, Zhe Wu, Chanhong Kim, Yuehui He, Jiamu Du
Summary: Research shows that CONSTANS (CO) is a master transcription factor in triggering the floral transition in plants and is closely related to the regulation of the FLOWERING LOCUS T (FT) gene. CO binds to NUCLEAR FACTOR-YB/YC and forms a high affinity and specificity for the FT promoter through multivalent binding, regulating the transition of floral period.