Inhibition of toll-like receptor 4 alleviates hyperalgesia induced by acute dural inflammation in experimental migraine

Pathophysiology of Migraine: A Disorder of Sensory Processing

(2017) Peter J. Goadsby et al.   PHYSIOLOGICAL REVIEWS

Understanding migraine: Potential role of neurogenic inflammation

(2016) Rakesh Malhotra   Annals of Indian Academy of Neurology

Systemic TAK-242 prevents intrathecal LPS evoked hyperalgesia in male, but not female mice and prevents delayed allodynia following intraplantar formalin in both male and female mice: The role of TLR4 in the evolution of a persistent pain state

(2016) Sarah A. Woller et al.   BRAIN BEHAVIOR AND IMMUNITY

Rizatriptan overuse promotes hyperalgesia induced by dural inflammatory stimulation in rats by modulation of the serotonin system

(2016) Min Su et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

GBD 2015: migraine is the third cause of disability in under 50s

(2016) Timothy J. Steiner et al.   JOURNAL OF HEADACHE AND PAIN

Toll-like receptor 4 signaling in neurons of trigeminal ganglion contributes to nociception induced by acute pulpitis in rats

(2015) Jia-Ji Lin et al.   Scientific Reports

Spinal toll-like receptor 4-mediated signalling pathway contributes to visceral hypersensitivity induced by neonatal colonic irritation in rats

(2014) Z-Y. Chen et al.   EUROPEAN JOURNAL OF PAIN

Curcumin attenuates acute inflammatory injury by inhibiting the TLR4/MyD88/NF-κB signaling pathway in experimental traumatic brain injury

(2014) Hai-tao Zhu et al.   Journal of Neuroinflammation

Spinal HMGB1 induces TLR4-mediated long-lasting hypersensitivity and glial activation and regulates pain-like behavior in experimental arthritis

(2014) Nilesh M. Agalave et al.   PAIN

Cutaneous allodynia as a predictor of migraine chronification

(2013) Mark A. Louter et al.   BRAIN

A chronic animal model of migraine, induced by repeated meningeal nociception, characterized by a behavioral and pharmacological approach

(2013) Agustin Melo-Carrillo et al.   CEPHALALGIA

Blockade of Toll-Like Receptor 4 Attenuates Morphine Tolerance and Facilitates the Pain Relieving Properties of Morphine

(2013) L. N. Eidson et al.   JOURNAL OF NEUROSCIENCE

Sensitization and pain

(2013) Marco Aguggia et al.   NEUROLOGICAL SCIENCES

Migraine pathophysiology: Anatomy of the trigeminovascular pathway and associated neurological symptoms, cortical spreading depression, sensitization, and modulation of pain

(2013) Rodrigo Noseda et al.   PAIN

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Central sensitization: Implications for the diagnosis and treatment of pain

(2010) Clifford J. Woolf   PAIN

Medullary pain facilitating neurons mediate allodynia in headache-related pain

(2009) Rebecca M. Edelmayer et al.   ANNALS OF NEUROLOGY

The “Toll” of Opioid-Induced Glial Activation: Improving the Clinical Efficacy of Opioids by Targeting Glia

(2009) Linda R. Watkins et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Glial TLR4 receptor as new target to treat neuropathic pain: Efficacy of a new receptor antagonist in a model of peripheral nerve injury in mice

(2008) Isabella Bettoni et al.   GLIA