Disruption of De Novo Serine Synthesis in Müller Cells Induced Mitochondrial Dysfunction and Aggravated Oxidative Damage

Genome-wide analyses identify common variants associated with macular telangiectasia type 2

(2017) Thomas S Scerri et al.   NATURE GENETICS

PHGDH Expression Is Required for Mitochondrial Redox Homeostasis, Breast Cancer Stem Cell Maintenance, and Lung Metastasis

(2016) D. Samanta et al.   CANCER RESEARCH

A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate

(2016) Michael E Pacold et al.   Nature Chemical Biology

Identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancers

(2016) Edouard Mullarky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dysregulation of inter-photoreceptor retinoid-binding protein (IRBP) after induced Müller cell disruption

(2015) Ling Zhu et al.   JOURNAL OF NEUROCHEMISTRY

Glucose, lactate, and shuttling of metabolites in vertebrate retinas

(2015) James B. Hurley et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Cancer-like metabolism of the mammalian retina

(2014) Soo Khai Ng et al.   CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Mitochondrial One-Carbon Metabolism Maintains Redox Balance during Hypoxia

(2014) I. Martinez-Reyes et al.   Cancer Discovery

Characterization of the Usage of the Serine Metabolic Network in Human Cancer

(2014) Mahya Mehrmohamadi et al.   Cell Reports

Loss of Müller's Cells and Photoreceptors in Macular Telangiectasia Type 2

(2013) Michael B. Powner et al.   OPHTHALMOLOGY

Perifoveal Müller Cell Depletion in a Case of Macular Telangiectasia Type 2

(2010) Michael B. Powner et al.   OPHTHALMOLOGY

Antioxidant or neurotrophic factor treatment preserves function in a mouse model of neovascularization-associated oxidative stress

(2009) Michael I. Dorrell et al.   JOURNAL OF CLINICAL INVESTIGATION

l-Serine synthesis in the central nervous system: A review on serine deficiency disorders

(2009) L. Tabatabaie et al.   MOLECULAR GENETICS AND METABOLISM

Cellular signaling and factors involved in Müller cell gliosis: Neuroprotective and detrimental effects

(2009) Andreas Bringmann et al.   PROGRESS IN RETINAL AND EYE RESEARCH