Activation of Nrf2 Pathway Contributes to Neuroprotection by the Dietary Flavonoid Tiliroside

Inhibition of neuroinflammation by thymoquinone requires activation of Nrf2/ARE signalling

(2017) Ravikanth Velagapudi et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

AMPK and SIRT1 activation contribute to inhibition of neuroinflammation by thymoquinone in BV2 microglia

(2017) Ravikanth Velagapudi et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Inhibition of neuroinflammation in BV2 microglia by the biflavonoid kolaviron is dependent on the Nrf2/ARE antioxidant protective mechanism

(2016) Samuel A. Onasanwo et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

SIRT1 Deficiency in Microglia Contributes to Cognitive Decline in Aging and Neurodegeneration via Epigenetic Regulation of IL-1 

(2015) S.-H. Cho et al.   JOURNAL OF NEUROSCIENCE

Differential Roles of M1 and M2 Microglia in Neurodegenerative Diseases

(2015) Yu Tang et al.   MOLECULAR NEUROBIOLOGY

Linalool Inhibits LPS-Induced Inflammation in BV2 Microglia Cells by Activating Nrf2

(2015) Yang Li et al.   NEUROCHEMICAL RESEARCH

Low Dose Nicotine Attenuates Aβ Neurotoxicity through Activation Early Growth Response Gene 1 Pathway

(2015) Maoqiang Xue et al.   PLoS One

Redox Control of Microglial Function: Molecular Mechanisms and Functional Significance

(2014) Ana I. Rojo et al.   ANTIOXIDANTS & REDOX SIGNALING

Tiliroside, a dietary glycosidic flavonoid, inhibits TRAF-6/NF-κB/p38-mediated neuroinflammation in activated BV2 microglia

(2014) Ravikanth Velagapudi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Oxidative damage and the Nrf2-ARE pathway in neurodegenerative diseases

(2014) Li Gan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Heme oxygenase-1 deficiency accompanies neuropathogenesis of HIV-associated neurocognitive disorders

(2014) Alexander J. Gill et al.   JOURNAL OF CLINICAL INVESTIGATION

Punicalagin inhibits neuroinflammation in LPS-activated rat primary microglia

(2014) Olumayokun A. Olajide et al.   MOLECULAR NUTRITION & FOOD RESEARCH

5-Hydroxy-3,6,7,8,3′4′-hexamethoxyflavone inhibits nitric oxide production in lipopolysaccharide-stimulated BV2 microglia via NF-κB suppression and Nrf-2-dependent heme oxygenase-1 induction

(2013) Chang-Hee Kang et al.   FOOD AND CHEMICAL TOXICOLOGY

Crosstalk between Oxidative Stress and SIRT1: Impact on the Aging Process

(2013) Antero Salminen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

NRF2-regulation in brain health and disease: Implication of cerebral inflammation

(2013) Mats Sandberg et al.   NEUROPHARMACOLOGY

Protective effect of SIRT1 on toxicity of microglial-derived factors induced by LPS to PC12 cells via the p53-caspase-3-dependent apoptotic pathway

(2013) Jieming Ye et al.   NEUROSCIENCE LETTERS

Protection by chrysin, apigenin, and luteolin against oxidative stress is mediated by the Nrf2-dependent up-regulation of heme oxygenase 1 and glutamate cysteine ligase in rat primary hepatocytes

(2012) Chin-Shiu Huang et al.   ARCHIVES OF TOXICOLOGY

SIRT1 Is Required for AMPK Activation and the Beneficial Effects of Resveratrol on Mitochondrial Function

(2012) Nathan L. Price et al.   Cell Metabolism

SIRT1 Regulates CD40 Expression Induced by TNF-a via NF-?B Pathway in Endothelial Cells

(2012) Lina Yang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Flavonoids Protect Cerebrovascular Endothelial Cells through Nrf2 and PI3K from β-Amyloid Peptide-Induced Oxidative Damage

(2012) Yuan-Di Xi et al.   CURRENT NEUROVASCULAR RESEARCH

Alzheimer’s Disease-Associated Neurotoxic Peptide Amyloid-Β Impairs Base Excision Repair in Human Neuroblastoma Cells

(2012) Anne Forestier et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

TGFβ signalling plays an important role in IL4-induced alternative activation of microglia

(2012) Xiaolai Zhou et al.   Journal of Neuroinflammation

Pharmacological Targeting of the Transcription Factor Nrf2 at the Basal Ganglia Provides Disease Modifying Therapy for Experimental Parkinsonism

(2011) Agnieszka Jazwa et al.   ANTIOXIDANTS & REDOX SIGNALING

Nuclear factor p65 interacts with Keap1 to repress the Nrf2-ARE pathway

(2011) Miao Yu et al.   CELLULAR SIGNALLING

The role of COX-2 and Nrf2/ARE in anti-inflammation and antioxidative stress: Aging and anti-aging

(2011) Cheng Luo et al.   MEDICAL HYPOTHESES

When NRF2 Talks, Who's Listening?

(2010) Nobunao Wakabayashi et al.   ANTIOXIDANTS & REDOX SIGNALING

Anti-inflammatory activity of xanthohumol involves heme oxygenase-1 induction via NRF2-ARE signaling in microglial BV2 cells

(2010) Ik-Soo Lee et al.   NEUROCHEMISTRY INTERNATIONAL

Nrf2 regulates microglial dynamics and neuroinflammation in experimental Parkinson's disease

(2009) Ana I. Rojo et al.   GLIA

(−)-Epigallocatechin gallate induces Nrf2-mediated antioxidant enzyme expression via activation of PI3K and ERK in human mammary epithelial cells

(2008) Hye-Kyung Na et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Activation of Nrf2-antioxidant signaling attenuates NFκB-inflammatory response and elicits apoptosis

(2008) Wenge Li et al.   BIOCHEMICAL PHARMACOLOGY