Dual role of Par-4 in abrogation of EMT and switching on Mesenchymal to Epithelial Transition (MET) in metastatic pancreatic cancer cells

Long-term survivors of pancreatic adenocarcinoma show low rates of genetic alterations in KRAS, TP53 and SMAD4

(2018) Michele Masetti et al.   Cancer Biomarkers

E-Cadherin repression increases amount of cancer stem cells in human A549 lung adenocarcinoma and stimulates tumor growth

(2016) M. Farmakovskaya et al.   CELL CYCLE

Mesenchymal to Epithelial Transition Induced by Reprogramming Factors Attenuates the Malignancy of Cancer Cells

(2016) Mikiro Takaishi et al.   PLoS One

A therapeutically relevant, 3,3′-diindolylmethane derivative NGD16 attenuates angiogenesis by targeting glucose regulated protein, 78 kDa (GRP78)

(2015) Debasis Nayak et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Par-4 dependent modulation of cellular β-catenin by medicinal plant natural product derivative 3-azido Withaferin A

(2015) Hina Amin et al.   MOLECULAR CARCINOGENESIS

Arylquins target vimentin to trigger Par-4 secretion for tumor cell apoptosis

(2014) Ravshan Burikhanov et al.   Nature Chemical Biology

NF- B, an Active Player in Human Cancers

(2014) Y. Xia et al.   Cancer Immunology Research

The complexity of NF-κB signaling in inflammation and cancer

(2013) Bastian Hoesel et al.   Molecular Cancer

Novel Pancreatic Cancer Cell Lines Derived from Genetically Engineered Mouse Models of Spontaneous Pancreatic Adenocarcinoma: Applications in Diagnosis and Therapy

(2013) María P. Torres et al.   PLoS One

ETS-1 Protein Regulates Vascular Endothelial Growth Factor-induced Matrix Metalloproteinase-9 and Matrix Metalloproteinase-13 Expression in Human Ovarian Carcinoma Cell Line SKOV-3

(2012) Sonali Ghosh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Novel MMP-2 Inhibitor 3-azidowithaferin A (3-azidoWA) Abrogates Cancer Cell Invasion and Angiogenesis by Modulating Extracellular Par-4

(2012) Bilal Rah et al.   PLoS One

Design and synthesis of novel N,N′-glycoside derivatives of 3,3′-diindolylmethanes as potential antiproliferative agents

(2012) Deepak K. Sharma et al.   MedChemComm

Bone morphogenetic protein-7 regulates Snail signaling in carbon tetrachloride-induced fibrosis in the rat liver

(2012) WAN-RONG BI et al.   Experimental and Therapeutic Medicine

Inhibition of Fatty Acid Synthase and Sp1 Expression by 3,3′-Diindolylmethane in Human Breast Cancer Cells

(2011) George E. Saati et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Epithelial and mesenchymal phenotypic switchings modulate cell motility in metastasis

(2010) Alan Wells   Frontiers in Bioscience-Landmark

Cancer-selective apoptotic effects of extracellular and intracellular Par-4

(2010) T Shrestha-Bhattarai et al.   ONCOGENE

Expression of Prostate Apoptosis Response (Par-4) Is Associated with Progesterone Receptor in Breast Cancer

(2009) Pablo Zapata-Benavides et al.   ARCHIVES OF MEDICAL RESEARCH

Bone morphogenetic protein 7 induces mesenchymal-to-epithelial transition in melanoma cells, leading to inhibition of metastasis

(2009) Yi-Rang Na et al.   CANCER SCIENCE

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

(2009) Ulrich Wellner et al.   NATURE CELL BIOLOGY

Inhibition of SHP2 leads to mesenchymal to epithelial transition in breast cancer cells

(2008) X-D Zhou et al.   CELL DEATH AND DIFFERENTIATION

E-cadherin as an indicator of mesenchymal to epithelial reverting transitions during the metastatic seeding of disseminated carcinomas

(2008) Alan Wells et al.   CLINICAL & EXPERIMENTAL METASTASIS

Chemoprevention of Pancreatic Cancer: Characterization of Par-4 and its Modulation by 3,3′ Diindolylmethane (DIM)

(2008) Asfar Sohail Azmi et al.   PHARMACEUTICAL RESEARCH

Twist is a transcriptional repressor of E-cadherin gene expression in breast cancer

(2007) Farhad Vesuna et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS