LDHA is a direct target of miR-30d-5p and contributes to aggressive progression of gallbladder carcinoma

PDL1 And LDHA act as ceRNAs in triple negative breast cancer by regulating miR-34a

(2017) Xiaojia Huang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Efficacy and Safety of Capecitabine, Irinotecan, Gemcitabine, and Bevacizumab as Second-Line Treatment in Advanced Biliary Tract Cancer: A Phase II Study

(2017) Finn Ole Larsen et al.   ONCOLOGY

Gallbladder cancer epidemiology, pathogenesis and molecular genetics: Recent update

(2017) Aarti Sharma et al.   WORLD JOURNAL OF GASTROENTEROLOGY

MiR-200c inhibits bladder cancer progression by targeting lactate dehydrogenase A

(2017) Daozhang Yuan et al.   Oncotarget

The Warburg effect as an adaptation of cancer cells to rapid fluctuations in energy demand

(2017) Tamir Epstein et al.   PLoS One

Suppression of lactate dehydrogenase A compromises tumor progression by downregulation of the Warburg effect in glioblastoma

(2016) Juan Li et al.   NEUROREPORT

Identification of miR-30b-3p and miR-30d-5p as direct regulators of androgen receptor signaling in prostate cancer by complementary functional microRNA library screening

(2016) Binod Kumar et al.   Oncotarget

Up-regulation of PKM2 promote malignancy and related to adverse prognostic risk factor in human gallbladder cancer

(2016) Wei Lu et al.   Scientific Reports

Fundamentals of cancer metabolism

(2016) R. J. DeBerardinis et al.   Science Advances

Long-Term Outcomes and Prognostic Factors in Advanced Gallbladder Cancer: Focus on the Advanced T Stage

(2016) Chen Chen et al.   PLoS One

MicroRNA-30d-5p inhibits tumour cell proliferation and motility by directly targeting CCNE2 in non-small cell lung cancer

(2015) Di Chen et al.   CANCER LETTERS

Therapeutic Targeting of the Warburg Effect in Pancreatic Cancer Relies on an Absence of p53 Function

(2015) N. V. Rajeshkumar et al.   CANCER RESEARCH

MiR-199a-5p is negatively associated with malignancies and regulates glycolysis and lactate production by targeting hexokinase 2 in liver cancer

(2015) Weijie Guo et al.   HEPATOLOGY

The c-Myc–LDHA axis positively regulates aerobic glycolysis and promotes tumor progression in pancreatic cancer

(2015) Tian-Lin He et al.   MEDICAL ONCOLOGY

Different effects of LDH-A inhibition by oxamate in non-small cell lung cancer cells

(2015) Yang Yang et al.   Oncotarget

Targeting Lactate Dehydrogenase-A Inhibits Tumorigenesis and Tumor Progression in Mouse Models of Lung Cancer and Impacts Tumor-Initiating Cells

(2014) Han Xie et al.   Cell Metabolism

FOXM1 Promotes the Warburg Effect and Pancreatic Cancer Progression via Transactivation of LDHA Expression

(2014) J. Cui et al.   CLINICAL CANCER RESEARCH

MicroRNA-1 (miR-1) inhibits chordoma cell migration and invasion by targeting slug

(2014) Eiji Osaka et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Lactate Dehydrogenase A is a potential prognostic marker in clear cell renal cell carcinoma

(2014) Hala Girgis et al.   Molecular Cancer

Lysine-5 Acetylation Negatively Regulates Lactate Dehydrogenase A and Is Decreased in Pancreatic Cancer

(2013) Di Zhao et al.   CANCER CELL

Relationships between LDH-A, Lactate, and Metastases in 4T1 Breast Tumors

(2013) A. Rizwan et al.   CLINICAL CANCER RESEARCH

Lactate dehydrogenase a in cancer: A promising target for diagnosis and therapy

(2013) Ping Miao et al.   IUBMB LIFE

Knockdown of lactate dehydrogenase A suppresses tumor growth and metastasis of human hepatocellular carcinoma

(2012) Shi L. Sheng et al.   FEBS Journal

Roles of microRNA on cancer cell metabolism

(2012) Bing Chen et al.   Journal of Translational Medicine

ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect

(2012) Weiwei Yang et al.   NATURE CELL BIOLOGY

Analysis of the combined action of miR-143 and miR-145 on oncogenic pathways in colorectal cancer cells reveals a coordinate program of gene repression

(2012) A Pagliuca et al.   ONCOGENE

Development of molecularly targeted therapies in biliary tract cancers: Reassessing the challenges and opportunities

(2011) Andrew X. Zhu et al.   HEPATOLOGY

A Combined Proteomics and Metabolomics Profiling of Gastric Cardia Cancer Reveals Characteristic Dysregulations in Glucose Metabolism

(2010) Zhen Cai et al.   MOLECULAR & CELLULAR PROTEOMICS