Long noncoding RNA HULC accelerates liver cancer by inhibiting PTEN via autophagy cooperation to miR15a

Long noncoding RNA MEG3 suppresses liver cancer cells growth through inhibiting β-catenin by activating PKM2 and inactivating PTEN

(2018) Qidi Zheng et al.   Cell Death & Disease

MicroRNA-300 Regulates the Ubiquitination of PTEN through the CRL4B DCAF13 E3 Ligase in Osteosarcoma Cells

(2018) Zhi Chen et al.   Molecular Therapy-Nucleic Acids

Dysregulated long noncoding RNAs (lncRNAs) in hepatocellular carcinoma: implications for tumorigenesis, disease progression, and liver cancer stem cells

(2017) Xiaoqi Huo et al.   Molecular Cancer

The lncRNA HULC functions as an oncogene by targeting ATG7 and ITGB1 in epithelial ovarian carcinoma

(2017) Shuo Chen et al.   Cell Death & Disease

miR-18a promotes cell proliferation of esophageal squamous cell carcinoma cells by increasing cylin D1 via regulating PTEN-PI3K-AKT-mTOR signaling axis

(2016) Weiguo Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Enzymatic Analysis of PTEN Ubiquitylation by WWP2 and NEDD4-1 E3 Ligases

(2016) Zan Chen et al.   BIOCHEMISTRY

Long Noncoding RNA Highly Upregulated in Liver Cancer Regulates the Tumor Necrosis Factor-α-Induced Apoptosis in Human Vascular Endothelial Cells

(2016) Yongjiang Ma et al.   DNA AND CELL BIOLOGY

miR‐10b expression in breast cancer stem cells supports self‐renewal through negative PTEN regulation and sustained AKT activation

(2016) Ivan Bahena‐Ocampo et al.   EMBO REPORTS

Expression patterns of sirtuin 1-AMPK-autophagy pathway in chronic colitis and inflammation-associated colon neoplasia in IL-10-deficient mice

(2016) Elena Talero et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The ubiquitin-proteasome system and autophagy: Coordinated and independent activities

(2016) Victoria Cohen-Kaplan et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Notch promotes tumor metastasis in a prostate-specific Pten-null mouse model

(2016) Oh-Joon Kwon et al.   JOURNAL OF CLINICAL INVESTIGATION

The long noncoding RNA HOTAIR activates autophagy by upregulating ATG3 and ATG7 in hepatocellular carcinoma

(2016) Liang Yang et al.   Molecular BioSystems

Autophagy Regulates Chromatin Ubiquitination in DNA Damage Response through Elimination of SQSTM1/p62

(2016) Yanan Wang et al.   MOLECULAR CELL

Induction of genomic instability and activation of autophagy in artificial human aneuploid cells

(2016) Kentaro Ariyoshi et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

PTEN enables the development of pre-B acute lymphoblastic leukemia

(2016) Jérôme Fortin et al.   NATURE MEDICINE

MicroRNA-15a Inhibits Proliferation and Induces Apoptosis in CNE1 Nasopharyngeal Carcinoma Cells

(2016) Kang Zhu et al.   ONCOLOGY RESEARCH

Pten loss promotes MAPK pathway dependency in HER2/neu breast carcinomas

(2016) Saya H. Ebbesen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AKT activation controls cell survival in response to HDAC6 inhibition

(2016) M Kaliszczak et al.   Cell Death & Disease

Analysis of PI3K pathway components in human cancers

(2016) JAMILA DARAGMEH et al.   Oncology Letters

Beta 1-integrin–c-Met cooperation reveals an inside-in survival signalling on autophagy-related endomembranes

(2016) Rachel Barrow-McGee et al.   Nature Communications

Cdh1 inhibits WWP2-mediated ubiquitination of PTEN to suppress tumorigenesis in an APC-independent manner

(2016) Jia Liu et al.   Cell Discovery

A novel mouse model of intrahepatic cholangiocarcinoma induced by liver-specific Kras activation and Pten deletion

(2016) Tsuneo Ikenoue et al.   Scientific Reports

Autophagy is induced in the skeletal muscle of cachectic cancer patients

(2016) Zaira Aversa et al.   Scientific Reports

HULC cooperates with MALAT1 to aggravate liver cancer stem cells growth through telomere repeat-binding factor 2

(2016) Mengying Wu et al.   Scientific Reports

Upregulation of ATG3 contributes to autophagy induced by the detachment of intestinal epithelial cells from the extracellular matrix, but promotes autophagy-independent apoptosis of the attached cells

(2015) Byong Hoon Yoo et al.   Autophagy

TP53INP2/DOR protein chaperones deacetylated nuclear LC3 to the cytoplasm to promote macroautophagy

(2015) Xu Liu et al.   Autophagy

Long Noncoding RNA HULC Modulates Abnormal Lipid Metabolism in Hepatoma Cells through an miR-9-Mediated RXRA Signaling Pathway

(2015) M. Cui et al.   CANCER RESEARCH

HULC and Linc00152 Act as Novel Biomarkers in Predicting Diagnosis of Hepatocellular Carcinoma

(2015) Jun Li et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

LC3- and p62-based biochemical methods for the analysis of autophagy progression in mammalian cells

(2015) Peidu Jiang et al.   METHODS

A Nuclear Option That Initiates Autophagy

(2015) Lyndsay Murrow et al.   MOLECULAR CELL

MicroRNA-212 negatively regulates starvation induced autophagy in prostate cancer cells by inhibiting SIRT1 and is a modulator of angiogenesis and cellular senescence

(2015) Malathi Ramalinga et al.   Oncotarget

A Long Noncoding RNA Perturbs the Circadian Rhythm of Hepatoma Cells to Facilitate Hepatocarcinogenesis

(2015) Ming Cui et al.   NEOPLASIA

Choline dehydrogenase interacts with SQSTM1/p62 to recruit LC3 and stimulate mitophagy

(2014) Sungwoo Park et al.   Autophagy

Long noncoding RNA HULC is a novel biomarker of poor prognosis in patients with pancreatic cancer

(2014) Wei Peng et al.   MEDICAL ONCOLOGY

HMGB1-mediated autophagy promotes docetaxel resistance in human lung adenocarcinoma

(2014) Banzhou Pan et al.   Molecular Cancer

Hypermethylation and down-regulation of DLEU2 in paediatric acute myeloid leukaemia independent of embedded tumour suppressor miR-15a/16-1

(2014) Leah Morenos et al.   Molecular Cancer

Posttranscriptional destabilization of the liver-specific long noncoding RNA HULC by the IGF2 mRNA-binding protein 1 (IGF2BP1)

(2013) Monika Hämmerle et al.   HEPATOLOGY

Role of long non-coding RNA HULC in cell proliferation, apoptosis and tumor metastasis of gastric cancer: A clinical and in vitro investigation

(2013) YAN ZHAO et al.   ONCOLOGY REPORTS

The role of MTMR14 in autophagy and in muscle disease

(2010) Elizabeth M. Gibbs et al.   Autophagy

CREB up-regulates long non-coding RNA, HULC expression through interaction with microRNA-372 in liver cancer

(2010) Jiayi Wang et al.   NUCLEIC ACIDS RESEARCH

PTEN inhibits BMI1 function independently of its phosphatase activity

(2009) Catherine Fan et al.   Molecular Cancer