YAP promotes proliferation, chemoresistance, and angiogenesis in human cholangiocarcinoma through TEAD transcription factors

Hippo Pathway Activity Influences Liver Cell Fate

(2014) Dean Yimlamai et al.   CELL

Activation of β-Catenin and Yap1 in Human Hepatoblastoma and Induction of Hepatocarcinogenesis in Mice

(2014) Junyan Tao et al.   GASTROENTEROLOGY

Biliary repair and carcinogenesis are mediated by IL-33–dependent cholangiocyte proliferation

(2014) Jun Li et al.   JOURNAL OF CLINICAL INVESTIGATION

YAP activation is an early event and a potential therapeutic target in liver cancer development

(2014) Andrea Perra et al.   JOURNAL OF HEPATOLOGY

Guidelines for the diagnosis and management of intrahepatic cholangiocarcinoma

(2014) John Bridgewater et al.   JOURNAL OF HEPATOLOGY

Cholangiocarcinoma

(2014) Nataliya Razumilava et al.   LANCET

The Hippo Tumor Suppressor Network: From Organ Size Control to Stem Cells and Cancer

(2013) G. Halder et al.   CANCER RESEARCH

The TEAD4-YAP/TAZ Protein-Protein Interaction: Expected Similarities and Unexpected Differences

(2013) Jean Christophe Hau et al.   CHEMBIOCHEM

Molecular Pathways: YAP and TAZ Take Center Stage in Organ Growth and Tumorigenesis

(2013) S. Piccolo et al.   CLINICAL CANCER RESEARCH

The Hippo superhighway: signaling crossroads converging on the Hippo/Yap pathway in stem cells and development

(2013) Evan R Barry et al.   CURRENT OPINION IN CELL BIOLOGY

Molecular Signatures of Tissue-Specific Microvascular Endothelial Cell Heterogeneity in Organ Maintenance and Regeneration

(2013) Daniel J. Nolan et al.   DEVELOPMENTAL CELL

G13 Controls Angiogenesis through Regulation of VEGFR-2 Expression

(2013) Kishor Kumar Sivaraj et al.   DEVELOPMENTAL CELL

Yes-Associated Protein Up-regulates Jagged-1 and Activates the NOTCH Pathway in Human Hepatocellular Carcinoma

(2013) Darjus Felix Tschaharganeh et al.   GASTROENTEROLOGY

Integrative Molecular Analysis of Intrahepatic Cholangiocarcinoma Reveals 2 Classes That Have Different Outcomes

(2013) Daniela Sia et al.   GASTROENTEROLOGY

Intrahepatic cholangiocarcinoma: pathogenesis and rationale for molecular therapies

(2013) D Sia et al.   ONCOGENE

Thymic epithelial cell expansion through matricellular protein CYR61 boosts progenitor homing and T-cell output

(2013) Yalin Emre et al.   Nature Communications

Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP

(2012) Y. Liu-Chittenden et al.   GENES & DEVELOPMENT

Constitutive Notch2 signaling induces hepatic tumors in mice

(2012) Michael T. Dill et al.   HEPATOLOGY

Restriction of intestinal stem cell expansion and the regenerative response by YAP

(2012) Evan R. Barry et al.   NATURE

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

Yap1 Acts Downstream of α-Catenin to Control Epidermal Proliferation

(2011) Karin Schlegelmilch et al.   CELL

Genomic and Genetic Characterization of Cholangiocarcinoma Identifies Therapeutic Targets for Tyrosine Kinase Inhibitors

(2011) Jesper B. Andersen et al.   GASTROENTEROLOGY

Yes-associated protein regulation of adaptive liver enlargement and hepatocellular carcinoma development in mice

(2011) Marta A. Kowalik et al.   HEPATOLOGY

The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal

(2011) Bin Zhao et al.   NATURE CELL BIOLOGY

Cholangiocarcinoma—controversies and challenges

(2011) Tushar Patel   Nature Reviews Gastroenterology & Hepatology

Cholangiocarcinoma: Update and future perspectives

(2010) Manuela Gatto et al.   DIGESTIVE AND LIVER DISEASE

The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version

(2010) B. Zhao et al.   GENES & DEVELOPMENT

Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver

(2010) L. Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Hippo-Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis

(2010) K.-P. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New insights on cholangiocarcinoma

(2010) Manuela Gatto   World Journal of Gastrointestinal Oncology

A Gene Signature Predictive for Outcome in Advanced Ovarian Cancer Identifies a Survival Factor: Microfibril-Associated Glycoprotein 2

(2009) Samuel C. Mok et al.   CANCER CELL

Mst1 and Mst2 Maintain Hepatocyte Quiescence and Suppress Hepatocellular Carcinoma Development through Inactivation of the Yap1 Oncogene

(2009) Dawang Zhou et al.   CANCER CELL

Clinical Significance of Cell Cycle–and Apoptosis-Related Markers in Biliary Tract Cancer

(2008) Eva Karamitopoulou et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Yes-associated protein (YAP) functions as a tumor suppressor in breast

(2008) M Yuan et al.   CELL DEATH AND DIFFERENTIATION

TEAD mediates YAP-dependent gene induction and growth control

(2008) B. Zhao et al.   GENES & DEVELOPMENT

Yap1 Phosphorylation by c-Abl Is a Critical Step in Selective Activation of Proapoptotic Genes in Response to DNA Damage

(2008) Dan Levy et al.   MOLECULAR CELL