Nrf2, but not β-catenin, mutation represents an early event in rat hepatocarcinogenesis

Genomic Profiling of Hepatocellular Adenomas Reveals Recurrent FRK-Activating Mutations and the Mechanisms of Malignant Transformation

(2014) Camilla Pilati et al.   CANCER CELL

Telomerase reverse transcriptase promoter mutation is an early somatic genetic alteration in the transformation of premalignant nodules in hepatocellular carcinoma on cirrhosis

(2014) Jean Charles Nault et al.   HEPATOLOGY

Computational modeling identifies key gene regulatory interactions underlying phenobarbital-mediated tumor promotion

(2014) Raphaëlle Luisier et al.   NUCLEIC ACIDS RESEARCH

The emerging role of the Nrf2-Keap1 signaling pathway in cancer

(2013) M. C. Jaramillo et al.   GENES & DEVELOPMENT

MicroRNA/gene profiling unveils early molecular changes and nuclear factor erythroid related factor 2 (NRF2) activation in a rat model recapitulating human hepatocellular carcinoma (HCC)

(2013) Annalisa Petrelli et al.   HEPATOLOGY

Identification of driver genes in hepatocellular carcinoma by exome sequencing

(2013) Sean P. Cleary et al.   HEPATOLOGY

Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming

(2012) Yoichiro Mitsuishi et al.   CANCER CELL

Epidemiology of Viral Hepatitis and Hepatocellular Carcinoma

(2012) Hashem B. El-Serag   GASTROENTEROLOGY

Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma

(2012) Cécile Guichard et al.   NATURE GENETICS

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Genomic modeling of tumor onset and progression in a mouse model of aggressive human liver cancer

(2011) Cédric Coulouarn et al.   CARCINOGENESIS

The Promoter of Human Telomerase Reverse Transcriptase Is Activated During Liver Regeneration and Hepatocyte Proliferation

(2011) Hüseyin Sirma et al.   GASTROENTEROLOGY

Nrf2 and Keap1 Abnormalities in Non-Small Cell Lung Carcinoma and Association with Clinicopathologic Features

(2010) L. M. Solis et al.   CLINICAL CANCER RESEARCH

Accelerated liver regeneration and hepatocarcinogenesis in mice overexpressing serine-45 mutant β-catenin

(2010) Kari N. Nejak-Bowen et al.   HEPATOLOGY

Evolution of genomic instability in diethylnitrosamine-induced hepatocarcinogenesis in mice

(2010) Kristina Aleksic et al.   HEPATOLOGY

The molecular determinants of de novo nucleotide biosynthesis in cancer cells

(2009) Xuemei Tong et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Progenitor-derived hepatocellular carcinoma model in the rat

(2009) Jesper B. Andersen et al.   HEPATOLOGY

COSMIC (the Catalogue of Somatic Mutations in Cancer): a resource to investigate acquired mutations in human cancer

(2009) Simon A. Forbes et al.   NUCLEIC ACIDS RESEARCH

Introducing the “TCDD-Inducible AhR-Nrf2 Gene Battery”

(2009) Ronnie L. Yeager et al.   TOXICOLOGICAL SCIENCES

Tumor Cell Metabolism: Cancer's Achilles' Heel

(2008) Guido Kroemer et al.   CANCER CELL

Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2

(2008) X.-J. Wang et al.   CARCINOGENESIS

Correlation between β-catenin mutations and expression of Wnt-signaling target genes in hepatocellular carcinoma

(2008) Madeleine Austinat et al.   Molecular Cancer

Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy

(2008) T. Shibata et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA