Antibodies to an interfering epitope in hepatitis C virus E2 can mask vaccine-induced neutralizing activity

Hepatitis C virus therapy in the direct acting antiviral era

(2014) Mitchell L. Shiffman   CURRENT OPINION IN GASTROENTEROLOGY

T-cell immunity and hepatitis C virus reinfection after cure of chronic hepatitis C with an interferon-free antiviral regimen in a chimpanzee

(2014) Benoit Callendret et al.   HEPATOLOGY

Naturally selected hepatitis C virus polymorphisms confer broad neutralizing antibody resistance

(2014) Justin R. Bailey et al.   JOURNAL OF CLINICAL INVESTIGATION

Structural Flexibility of a Conserved Antigenic Region in Hepatitis C Virus Glycoprotein E2 Recognized by Broadly Neutralizing Antibodies

(2014) Annalisa Meola et al.   JOURNAL OF VIROLOGY

Recombinant Hepatitis C Virus Envelope Glycoprotein Vaccine Elicits Antibodies Targeting Multiple Epitopes on the Envelope Glycoproteins Associated with Broad Cross-Neutralization

(2014) J. A. J.-X. Wong et al.   JOURNAL OF VIROLOGY

Structure of the core ectodomain of the hepatitis C virus envelope glycoprotein 2

(2014) Abdul Ghafoor Khan et al.   NATURE

Discrete conformations of epitope II on the hepatitis C virus E2 protein for antibody-mediated neutralization and nonneutralization

(2014) L. Deng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Hepatitis C Virus (HCV) Vaccine Comprising Envelope Glycoproteins gpE1/gpE2 Derived from a Single Isolate Elicits Broad Cross-Genotype Neutralizing Antibodies in Humans

(2013) John Lok Man Law et al.   PLoS One

Structural evidence for a bifurcated mode of action in the antibody-mediated neutralization of hepatitis C virus

(2013) L. Deng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hepatitis C Virus E2 Envelope Glycoprotein Core Structure

(2013) L. Kong et al.   SCIENCE

Prospects for Prophylactic and Therapeutic Vaccines Against Hepatitis C Virus

(2012) Stephen M. Feinstone et al.   CLINICAL INFECTIOUS DISEASES

Lack of full CD8 functional restoration after antiviral treatment for acute and chronic hepatitis C virus infection

(2012) Gabriele Missale et al.   GUT

Structure of Hepatitis C Virus Envelope Glycoprotein E2 Antigenic Site 412 to 423 in Complex with Antibody AP33

(2012) L. Kong et al.   JOURNAL OF VIROLOGY

Amino Acid Residue-Specific Neutralization and Nonneutralization of Hepatitis C Virus by Monoclonal Antibodies to the E2 Protein

(2012) H. Duan et al.   JOURNAL OF VIROLOGY

Cooperativity in Virus Neutralization by Human Monoclonal Antibodies to Two Adjacent Regions Located at the Amino Terminus of Hepatitis C Virus E2 Glycoprotein

(2012) Z. Keck et al.   JOURNAL OF VIROLOGY

Structural basis of hepatitis C virus neutralization by broadly neutralizing antibody HCV1

(2012) L. Kong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neutralization Interfering Antibodies: A “Novel” Example of Humoral Immune Dysfunction Facilitating Viral Escape?

(2012) Mancini Nicasio et al.   Viruses-Basel

The role of neutralizing antibodies in hepatitis C virus infection

(2011) V. C. Edwards et al.   JOURNAL OF GENERAL VIROLOGY

Immunization of Human Volunteers With Hepatitis C Virus Envelope Glycoproteins Elicits Antibodies That Cross-Neutralize Heterologous Virus Strains

(2011) Zania Stamataki et al.   JOURNAL OF INFECTIOUS DISEASES

Naturally Occurring Antibodies That Recognize Linear Epitopes in the Amino Terminus of the Hepatitis C Virus E2 Protein Confer Noninterfering, Additive Neutralization

(2011) A. W. Tarr et al.   JOURNAL OF VIROLOGY

New neutralizing antibody epitopes in hepatitis C virus envelope glycoproteins are revealed by dissecting peptide recognition profiles

(2011) Alla Kachko et al.   VACCINE

Meta-Analysis of Hepatitis C Virus Vaccine Efficacy in Chimpanzees Indicates an Importance for Structural Proteins

(2010) Harel Dahari et al.   GASTROENTEROLOGY

Characterization of Antibodies Induced by Vaccination with Hepatitis C Virus Envelope Glycoproteins

(2010) Ranjit Ray et al.   JOURNAL OF INFECTIOUS DISEASES

Role of N-Linked Glycans in the Functions of Hepatitis C Virus Envelope Proteins Incorporated into Infectious Virions

(2010) F. Helle et al.   JOURNAL OF VIROLOGY

Comparison of Immune Restoration in Early versus Late Alpha Interferon Therapy against Hepatitis C Virus

(2010) M. S. Abdel-Hakeem et al.   JOURNAL OF VIROLOGY

Safety and immunogenicity of HCV E1E2 vaccine adjuvanted with MF59 administered to healthy adults

(2010) Sharon E. Frey et al.   VACCINE

Depletion of interfering antibodies in chronic hepatitis C patients and vaccinated chimpanzees reveals broad cross-genotype neutralizing activity

(2009) P. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Broadly neutralizing human monoclonal antibodies to the hepatitis C virus E2 glycoprotein

(2008) A. M. Owsianka et al.   JOURNAL OF GENERAL VIROLOGY

Avoiding the void: cell-to-cell spread of human viruses

(2008) Quentin Sattentau   NATURE REVIEWS MICROBIOLOGY