Activation of the transforming growth factor-β/SMAD transcriptional pathway underlies a novel tumor-promoting role of sulfatase 1 in hepatocellular carcinoma

Transforming Growth Factor-  as a Therapeutic Target in Hepatocellular Carcinoma

(2014) G. Giannelli et al.   CANCER RESEARCH

Molecular mechanisms of epithelial–mesenchymal transition

(2014) Samy Lamouille et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Heparan sulfate signaling in cancer

(2014) Erik H. Knelson et al.   TRENDS IN BIOCHEMICAL SCIENCES

MicroRNA-21 suppresses PTEN and hSulf-1 expression and promotes hepatocellular carcinoma progression through AKT/ERK pathways

(2013) Longlong Bao et al.   CANCER LETTERS

The human sulfatase 2 inhibitor 2,4-disulfonylphenyl-tert-butylnitrone (OKN-007) has an antitumor effect in hepatocellular carcinoma mediated via suppression of TGFB1/SMAD2 and Hedgehog/GLI1 signaling

(2012) Xin Zheng et al.   GENES CHROMOSOMES & CANCER

Meta-Analysis of Gene Expression Signatures Defining the Epithelial to Mesenchymal Transition during Cancer Progression

(2012) Christian J. Gröger et al.   PLoS One

Sulfatase 1 and sulfatase 2 in hepatocellular carcinoma: Associated signaling pathways, tumor phenotypes, and survival

(2010) Ju Dong Yang et al.   GENES CHROMOSOMES & CANCER

The oncogenic effect of sulfatase 2 in human hepatocellular carcinoma is mediated in part by glypican 3-dependent Wnt activation

(2010) Jin-Ping Lai et al.   HEPATOLOGY

Sulfatase 2 protects hepatocellular carcinoma cells against apoptosis induced by the PI3K inhibitor LY294002 and ERK and JNK kinase inhibitors

(2010) Jin-Ping Lai et al.   LIVER INTERNATIONAL

Additive effect of apicidin and doxorubicin in sulfatase 1 expressing hepatocellular carcinoma in vitro and in vivo

(2009) Jin-Ping Lai et al.   JOURNAL OF HEPATOLOGY

TβRIII suppresses non-small cell lung cancer invasiveness and tumorigenicity

(2008) Elizabeth C. Finger et al.   CARCINOGENESIS

Heparin-degrading sulfatases in hepatocellular carcinoma: roles in pathogenesis and therapy targets

(2008) Jin-Ping Lai et al.   Future Oncology

Sulfatase 2 up-regulates glypican 3, promotes fibroblast growth factor signaling, and decreases survival in hepatocellular carcinoma

(2008) Jin-Ping Lai et al.   HEPATOLOGY