Article
Urology & Nephrology
Marie Dirix, Ester Philipse, Rowena Vleut, Vera Hartman, Bart Bracke, Thierry Chapelle, Geert Roeyen, Dirk Ysebaert, Gerda Van Beeumen, Erik Snelders, Annick Massart, Katrien Leyssens, Marie M. Couttenye, Daniel Abramowicz, Rachel Hellemans
Summary: The study emphasizes the importance of starting the transplant workup in a timely fashion for kidney transplant patients. Only 43% of patients initiated the workup before starting dialysis, and the completion time for the workup was unexpectedly long. The number of hospitalization days and language barriers were found to significantly impact the timing and duration of the transplant workup.
CLINICAL KIDNEY JOURNAL
(2022)
Article
Endocrinology & Metabolism
Eli Muchtar, Matthew T. Drake, Nelson Leung, Angela Dispenzieri, Martha Q. Lacy, Francis K. Buadi, David Dingli, Suzanne R. Hayman, Prashant Kapoor, Yi Lisa Hwa, Amie Fonder, Miriam Hobbs, Wilson Gonsalves, Taxiarchis Kourelis, Rahma Warsame, Stephen Russell, Ronald S. Go, Moritz Binder, Robert A. Kyle, S. Vincent Rajkumar, Shaji K. Kumar, Morie A. Gertz
Summary: The study found that vitamin D deficiency is common in AL amyloidosis patients, particularly among those with heavy proteinuria. Severe 25(OH)D deficiency at diagnosis predicts progression to end-stage renal disease.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Geriatrics & Gerontology
Ran-hui Cha, Seok Hui Kang, Mi Yeun Han, Won Suk An, Su-Hyun Kim, Jun Chul Kim
Summary: The addition of AST-120 to standard treatment in chronic kidney disease patients did not result in a significant difference in gait speed, but showed modest beneficial effects on gait speed change and quality of life, indicating potential to improve sarcopenia.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2022)
Article
Medicine, General & Internal
Ahmed Elderia, Ellen Kiehn, Ilija Djordjevic, Stephen Gerfer, Kaveh Eghbalzadeh, Christopher Gaisendrees, Antje-Christin Deppe, Elmar Kuhn, Thorsten Wahlers, Carolyn Weber
Summary: Infective endocarditis is associated with high morbidity and mortality in patients with chronic kidney disease and undergoing hemodialysis. This study found that patients on hemodialysis had the highest mortality rates, and staphylococcus aureus infection was an independent risk factor for 1-year mortality.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Immunology
Khalaf Kridin, Arieh Solomon, Rimma Laufer Britva, Dana Tzur Bitan, Arnon D. Cohen
Summary: The study found that patients with pyoderma gangrenosum (PG) have an increased risk of chronic renal failure (CRF), dialysis, and other kidney diseases (OKD), while individuals with a history of CRF, kidney transplantation (KT), and OKD have an increased likelihood of developing PG after diagnosis.
IMMUNOLOGIC RESEARCH
(2021)
Review
Nutrition & Dietetics
Heitor S. Ribeiro, Silvia G. R. Neri, Juliana S. Oliveira, Paul N. Bennett, Joao L. Viana, Ricardo M. Lima
Summary: Sarcopenia is associated with adverse outcomes in CKD patients, including mortality, hospitalization, and ESKD progression. Low muscle strength, low muscle mass, and low physical performance are specifically related to increased mortality risk in CKD patients.
CLINICAL NUTRITION
(2022)
Article
Medicine, General & Internal
Yi-Ping Chang, Chen-Mao Liao, Li-Hsin Wang, Hsiu-Hua Hu, Chih-Ming Lin
Summary: This study followed 1042 chronic kidney disease patients with Stage 3-5 kidney disease and found that estimated glomerular filtration rate and urine protein to creatinine ratio had strong predictive abilities for disease progression. Additionally, differences in predictive variables were observed among patients at different stages of kidney disease, suggesting the potential for tailored prevention strategies.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Pediatrics
Mohammed Azarudeen, Nivedita Kamath, A. V. Lalitha, Anil Vasudevan
Summary: Uremic encephalopathy and access-related infections are the most common emergencies in children with chronic kidney disease (CKD). Incidentally diagnosed CKD children have worse clinical profile and outcome.
Article
Geriatrics & Gerontology
Thomas J. Wilkinson, Joanne Miksza, Francesco Zaccardi, Claire Lawson, Andrew C. Nixon, Hannah M. L. Young, Kamlesh Khunti, Alice C. Smith
Summary: Frailty is common in individuals with chronic kidney disease (CKD) and is associated with adverse outcomes, including mortality and risk of end-stage kidney disease (ESKD). Preventative interventions should be initiated to mitigate the development of frailty. The use of a simple frailty index, generated electronically from health records, can predict outcomes and may aid prioritization for management of people with frailty.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2022)
Article
Cardiac & Cardiovascular Systems
Yoichiro Otaki, Tetsu Watanabe, Mari Shimizu, Shingo Tachibana, Junya Sato, Yuta Kobayashi, Yuji Saito, Tomonori Aono, Harutoshi Tamura, Shigehiko Kato, Satoshi Nishiyama, Hiroki Takahashi, Takanori Arimoto, Masafumi Watanabe
Summary: This study aimed to investigate the predictive value of renal tubular damage on HF progression in patients with HFpEF and CKD. The study found that a high UBCR level was an independent predictor of HF-related events in HFpEF and CKD patients, and was associated with the severity and clinical outcomes of the disease.
Article
Nutrition & Dietetics
Sofia Cecchi, Silvio Di Stante, Sara Belcastro, Veronica Bertuzzi, Assunta Cardillo, Laura Diotallevi, Xhensila Grabocka, Hrissa Kulurianu, Mauro Martello, Valentina Nastasi, Osmy Paci Della Costanza, Francesca Pizzolante, Marina Di Luca
Summary: Supplemented very low-protein diet (sVLPD) has been effective in delaying the start of dialysis treatment for stage 5 chronic renal failure patients, but it may increase the risk of malnutrition and is difficult to implement. By prescribing sVLPD supplemented with essential amino acids instead of keto-analogues, the progression of chronic kidney disease was slowed down and the start of dialysis treatment was delayed without evidence of malnutrition.
Article
Medicine, General & Internal
Mariana Murea, Shahriar Moossavi, Alison J. Fletcher, Deanna N. Jones, Hiba Sheikh, Gregory Russell, Kamyar Kalantar-Zadeh
Summary: This study aims to investigate the feasibility and safety of incremental hemodialysis prescription for patients with incident dialysis-dependent kidney disease and residual kidney function. The primary outcomes include recruitment rate, adherence to treatment regimens, and incidence of volume overload and metabolic imbalances in patients requiring dialysis.
Article
Orthopedics
Louis Dagneaux, Afton K. Limberg, Douglas R. Osmon, Nelson Leung, Daniel J. Berry, Matthew P. Abdel
Summary: In patients undergoing two-stage exchange arthroplasty for infected total hip arthroplasties, the incidence of AKI was 7% in patients without pre-existing CKD and 28% in patients with CKD. Postoperative fluid depletion, ICU requirement, and acute atrial fibrillation were identified as independent predictors for AKI in patients without pre-existing CKD.
JOURNAL OF ARTHROPLASTY
(2021)
Article
Urology & Nephrology
Anna Buckenmayer, Nadja Siebler, Christian S. Haas
Summary: This study aimed to investigate the role of etiology, pre-existing chronic kidney disease (CKD), and infections in the renal outcome and mortality of acute kidney injury (AKI). The study found that the etiology of AKI and pre-existing CKD did not affect the combined endpoint of end-stage kidney disease and mortality. Patients with sepsis had the highest in-hospital mortality and longest hospital stay.
JOURNAL OF NEPHROLOGY
(2023)
Article
Pediatrics
Emre Leventoglu, Bahar Bueyuekkaragoez, Furkan cagri Kavas, Mert Can Hologlu, Akif Kavgaci, Kibriya Fidan, Aydin Dalgic, Sevcan A. Bakkaloglu, Fatma Sedef Tunaoglu, Oguz Soeylemezoglu
Summary: Cardiovascular diseases are the main causes of morbidity in children with chronic kidney disease (CKD). This study evaluates the use of electrocardiography (ECG) in detecting dangerous changes in CKD and kidney replacement therapies and compares its value in predicting cardiovascular outcomes with echocardiography. The findings suggest that ECG can be used to detect cardiovascular problems, especially in hemodialysis (HD) patients. ECG abnormalities suggestive of left ventricular hypertrophy (LVH) should prompt referrals for echocardiographic assessment.
EUROPEAN JOURNAL OF PEDIATRICS
(2023)