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MICRORNAS AS BIOMARKERS OF CARDIOVASCULAR DISEASES

期刊

KARDIOLOGIYA
卷 58, 期 1, 页码 66-71

出版社

RUSSIAN HEART FAILURE SOC
DOI: 10.18087/cardio.2018.1.10083

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chronic heart failure; microRNA; microRNA expression; diagnostics; biomarker

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The fact that microRNAs play an important role in the development and pathogenesis of cardiovascular disease is beyond doubt. This article provides a brief overview of recent data that relate to microRNA expression in various cardiovascular diseases. Detecting significant changes in the level of expression of these molecules in various diseases means that microRNAs can be considered to be potential biomarkers of human pathologies including heart failure. Studying the relationship between the mechanisms of cardiovascular disease and the level of expression of a variety of microRNAs, as well as establishing their exact relationships with the genes is an urgent problem and requires further research.

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